Results 131 to 140 of about 6,800,484 (255)

Multi-Agent Target Assignment and Path Finding for Intelligent Warehouse: A Cooperative Multi-Agent Deep Reinforcement Learning Perspective

open access: yes
Multi-agent target assignment and path planning (TAPF) are two key problems in intelligent warehouses. However, most literature only addresses one of these two problems separately.
Dongjie Zhu (8897999)   +5 more
core   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

Multi-Bernoulli sensor selection for multi-target tracking with unknown clutter and detection profiles

open access: yes, 2016
A new sensor-selection solution within a multi-Bernoulli-based multi-target tracking framework is presented. The proposed method is especially designed for the general multi-target tracking case with no prior knowledge of the clutter distribution or the ...
Amirali Khodadadian Gostar (19997892)   +2 more
core  

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

Liquid Metal Target Prototypes for EURISOL Project: Goals And Future Challenges

open access: yes
Poster is dedicated to the concepts of the EURISOL multi megawatt liquid metal target. One of the possible versions could be windowless target concept.
Kravalis, Kalvis   +3 more
core  

Multi-bernoulli sensor control for multi-target tracking

open access: yes, 2013
A new approach to solve the sensor control problem is proposed, formulated based on multi-object Bayes filtering in the partially observable Markov decision process (POMDP) context, where the multi-object states are assumed to be random finite sets with ...
Amirali Khodadadian Gostar (19997892)   +2 more
core  

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

open access: yesFEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen   +5 more
wiley   +1 more source

Overcoming the Challenges of Multi‐Target‐Directed Ligands for Alzheimer's Disease

open access: yes
The concept of multi‐target‐directed ligands has been quite successful within the drug discovery community, due to its potential to better address the multifactorial nature of complex diseases. However, translating one of these ligands into new drugs has
Uliassi, Elisa   +3 more
core   +1 more source

A minimal cellulosome‐like system in Cellulosilyticum lentocellum

open access: yesFEBS Open Bio, EarlyView.
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan   +2 more
wiley   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

open access: yesFEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

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