Results 51 to 60 of about 6,800,484 (255)

Multi-objective Path Planning for AUVs Based on Improved Whale Optimization Algorithms and Fluid Disturbance Algorithms

水下无人系统学报
To address the challenges of low path planning efficiency for autonomous undersea vehicle(AUV) in multi-target environments, as well as the limitations of the traditional whale optimization algorithm(WOA) in terms of susceptibility to local optima and ...
Yuhong MA, Wen PANG, Daqi ZHU
doaj   +1 more source

Optimal Dispatch Strategy for a Distribution Network Containing High-Density Photovoltaic Power Generation and Energy Storage under Multiple Scenarios

Inventions, 2023
To better consume high-density photovoltaics, in this article, the application of energy storage devices in the distribution network not only realizes the peak shaving and valley filling of the electricity load but also relieves the pressure on the grid ...
Langbo Hou, Heng Chen, Jinjun Wang, Shichao Qiao, Gang Xu, Honggang Chen, Tao Liu   +6 more
doaj   +1 more source

MULTI-TARGET TRACKING ALGORITHMS FOR CLUTTERED ENVIRONMENTS

, 2019
Multi-target tracking (MTT) is the problem to simultaneously estimate the number of targets and their states or trajectories. Numerous techniques have been developed for over 50 years, with a multitude of applications in many fields of study; however ...
Do hyeung Kim (8052491)
core   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Multi-Target In Silico Evaluation of New 2-Pyrazolines as Antimicrobial Agents

Chemistry Proceedings
The world today is being ravaged by the emergence and re-emergence of microbial infections caused by antimicrobial-resistant strains, brought about primarily by the frequent and perhaps unnecessary use of antimicrobial agents.
Zukhruf Salami, Asmau Hamza, Abdullahi Idris, Yusuf Jimoh   +3 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source