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Multicomponent reactions II [PDF]
Beilstein Journal of Organic Chemistry, 2014 The concept of multicomponent reactions (MCR) [1] has been around in organic chemistry since the very early days. Indeed, the first example known in literature, the Strecker synthesis of α-aminonitriles [2], has been developed into an industrial process for the production of methionine in an annual scale of several hundreds of thousand tons per year ...
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The evaluation of chemoselectivity in multicomponent domino Knoevenagel/Diels-Alder reaction: A DFT study [PDF]
Journal of the Serbian Chemical Society, 2021 Herein, the chemoselectivity of the multicomponent domino Knoevenagel/ Diels–Alder reaction is investigated in terms of theoretical calculations. The structures of reagents, transition states, intermediates and products are optimized at the M062X/6-31+G ...
Attarbashi Mina +2 more
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Sequential and direct multicomponent reaction (MCR)-based dearomatization strategies.
Chemical Society Reviews, 2020 Dearomatization strategies in a multicomponent fashion often result in complex heterocyclic frameworks, which have attracted the attention of chemists due to their natural product-like structures. The combination of these two processes can easily achieve
U. Sharma +3 more
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Well-posedness analysis of multicomponent incompressible flow models [PDF]
, 2020 In this paper, we extend our study of mass transport in multicomponent isothermal fluids to the incompressible case. For a mixture, incompressibility is defined as the independence of average volume on pressure, and a weighted sum of the partial mass ...
Bothe, Dieter, Druet, Pierre-Etienne
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Molbank, 2017 A new compound belonging to the “heterostilbene” derivative, namely ethyl (E)-4-(2,4-dimethoxyphenyl)-6-(2,4-dimethoxystyryl)-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate (2), has been successfully synthesized as an unprecedented side product of the ...
Hery Suwito +6 more
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A Microfluidics Reaction System with Automation for a Multicomponent Reaction
Advanced Intelligent Systems, 2020 A multicomponent reaction is established toward quinazolimine derivatives, but it requires intensive human interventions in conventional reaction systems to suppress the side reactions. Herein, an automated microfluidics‐based reaction system that uses a
Xinlong Pang, Haoran Zhao, Shaohua Ma
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From sequence-defined macromolecules to macromolecular pin codes [PDF]
, 2020 Dynamic sequence-defined oligomers carrying a chemically written pin code are obtained through a strategy combining multicomponent reactions with the thermoreversible addition of 1,2,4-triazoline-3,5-diones (TADs) to indole substrates.
Badi, Nezha +4 more
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Catalyzed and non-catalyzed synthesis of bioactive monastrol
Química Nova, 2014 The bioactive 3,4-dihydropyrimidin-2(1H)-thione derivative known as Monastrol was synthesized under catalyzed and non-catalyzed conditions through the Biginelli multicomponent reaction under solvent-free conditions.
Haline G. O. Alvim +4 more
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Tetrazoles via Multicomponent Reactions [PDF]
Chemical Reviews, 2019 Tetrazole derivatives are a prime class of heterocycles, very important to medicinal chemistry and drug design due to not only their bioisosterism to carboxylic acid and amide moieties but also to their metabolic stability and other beneficial physicochemical properties.
Constantinos G. Neochoritis +2 more
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Green Processing and Synthesis, 2013 Atom-efficient multicomponent reactions (MCR) and step-efficient one-pot synthesis are developed for the synthesis of biaryl-substituted furocoumarins, furoquinolones, and furopyrimidines.
Kadam Asha +2 more
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