Results 31 to 40 of about 26,334 (117)

Strain and Complexity, Passerini and Ugi Reactions of Four‐Membered Heterocycles and Further Elaboration of TOSMIC Product

open access: yesChemistryOpen, 2023
Straightforward and general Passerini and Ugi procedures have been developed to incorporate four‐membered heterocycles into highly functionalized scaffolds.
Gábor Sztanó   +2 more
doaj   +1 more source

Tandem Catalysis of an Aldol-‘Click’ Reaction System within a Molecular Hydrogel

open access: yesMolecules, 2016
A heterogeneous supramolecular catalytic system for multicomponent aldol-‘click’ reactions is reported. The copper(I) metallohydrogel functionalized with a phenyltriazole fragment was able to catalyze the multicomponent reaction between phenylacetylene ...
Marco Araújo   +3 more
doaj   +1 more source

Multicomponent Hosomi–Sakurai Reaction on Isosorbide Derivatives

open access: yesMolecules
Trimethylsilyl ethers of monoprotected isosorbide derivatives have been subjected to multicomponent Hosomi–Sakurai reactions with allyl trimethylsilane and various aldehydes (aromatic or aliphatic) under the catalysis of trimethylsilyl triflate.
Luca Banfi   +5 more
doaj   +1 more source

A practical two-step procedure for the preparation of enantiopure pyridines: Multicomponent reactions of alkoxyallenes, nitriles and carboxylic acids followed by a cyclocondensation reaction

open access: yesBeilstein Journal of Organic Chemistry, 2011
A practical approach to highly functionalized 4-hydroxypyridine derivatives with stereogenic side chains in the 2- and 6-positions is described. The presented two-step process utilizes a multicomponent reaction of alkoxyallenes, nitriles and carboxylic ...
Christian Eidamshaus   +3 more
doaj   +1 more source

New synthetic method for the synthesis of 1,4-dihydropyridine using aminated multiwalled carbon nanotubes as high efficient catalyst and investigation of their antimicrobial properties

open access: yesJournal of Saudi Chemical Society, 2018
Synthesis of 1,4-dihydropyridines in the presence of aminated multiwalled carbon nanotubes and investigation into their antimicrobial properties were carried out.Amino functionalized carbon nanotubes were prepared through a facile, clean and safe ...
Roya Mahinpour   +3 more
doaj   +1 more source

Síntese do monastrol e novos compostos de Biginelli promovida por In(OTf)3 Synthesis of monastrol and of new Biginelli compounds promoted by In(OTf)3

open access: yesQuímica Nova, 2005
In this paper, we describe a practical route for the synthesis of Biginelli compounds using In(OTf)3. To study the generality of this catalyst, several examples using aromatic aldehydes, 1,3-dicarbonyl compounds, urea, and thiourea were investigated. The
Marla N. Godoi   +5 more
doaj   +1 more source

Novel Biopolymer-Based Catalyst for the Multicomponent Synthesis of N-aryl-4-aryl-Substituted Dihydropyridines Derived from Simple and Complex Anilines

open access: yesMolecules
Although Hantzsch synthesis has been an established multicomponent reaction method for more than a decade, its derivative, whereby an aniline replaces ammonium acetate as the nitrogen source, has not been explored at great length.
Giovanna Bosica, Roderick Abdilla
doaj   +1 more source

A general A³: coupling reaction based on functionalized alkynes

open access: yesQuímica Nova, 2013
A range of hydroxypropargylpiperidones were efficiently obtained by a one-pot three-component coupling reaction of aldehydes, alkynols, and a primary amine equivalent (4-piperidone hydrochloride hydrate) in ethyl acetate using copper(I) chloride as a ...
Edison P. Wendler, Alcindo A. Dos Santos
doaj   +1 more source

Copper-Catalyzed Four-Component A3-Based Cascade Reaction: Facile Synthesis of 3-Oxetanone-Derived Spirocycles

open access: yesChemistry
3-Oxetanone-derived spirooxazolidines represent a class of building blocks for accessing diverse saturated heterocycles, but their synthetic methods remain unexplored.
Rongkang Zhang   +3 more
doaj   +1 more source

In Silico and in Vitro Studies of Fluorinated Chroman-2-Carboxilic Acid Derivatives as an Anti-tubercular Agent

open access: yesFolia Medica, 2018
Background: Despite the use of traditional method, Ugi reaction currently is a well-established multicomponent reaction. Chromane motif itself possesses a variety of biological functions.
Kapadiya Khushal M.   +3 more
doaj   +1 more source

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