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Pseudo-multicomponent reactions. [PDF]

open access: yesRSC Adv, 2023
Classical multicomponent reactions (MCRs) are domino-type one-pot processes in which three or more different reactants are combined sequentially in the same reactor to synthesize compounds containing all or almost all atoms coming from the reactants ...
Flores-Reyes JC   +4 more
europepmc   +4 more sources

Multicomponent Reactions for the Synthesis of Active Pharmaceutical Ingredients [PDF]

open access: yesPharmaceuticals, 2022
Multicomponent reactions 9i.e., those that engage three or more starting materials to form a product that contains significant fragments of all of them), have been widely employed in the construction of compound libraries, especially in the context of ...
Ángel Cores   +3 more
doaj   +3 more sources

Formaldehyde surrogates in multicomponent reactions [PDF]

open access: yesBeilstein Journal of Organic Chemistry
Formaldehyde emerges as a cornerstone in multicomponent reactions, mainly prized for its robust reactivity. Yet, alongside these beneficial traits, this highly reactive C1-building block raises concerns, primarily regarding its toxicity.
Cecilia I. Attorresi   +2 more
doaj   +4 more sources

Multicomponent Reactions: "Kinderleicht". [PDF]

open access: yesJ Chem Educ, 2020
A demonstration experiment of the synthesis of a novel tetrazole derivative via a multicomponent reaction (Ugi tetrazole four component reaction, UT-4CR) bearing a luminol moiety and a subsequent exploitation of its chemiluminescent properties is ...
Neochoritis CG   +3 more
europepmc   +6 more sources

Bio-Catalysis in Multicomponent Reactions [PDF]

open access: yesMolecules, 2020
Enzyme catalysis is a very active research area in organic chemistry, because biocatalysts are compatible with and can be adjusted to many reaction conditions, as well as substrates.
Ndze Denis Jumbam, Wayiza Masamba
doaj   +5 more sources

Ni–citric acid coordination polymer as a practical catalyst for multicomponent reactions [PDF]

open access: yesScientific Reports, 2021
Coordinative polymers (CP) are a subclass of Metal–organic frameworks (MOFs) with porous microstructures which have been widely synthesized in recent years and applied in various fields especially in catalysis science. In this work Coordinative polymers (
Mostafa Koolivand   +4 more
doaj   +3 more sources

Multicomponent reactions [PDF]

open access: diamondBeilstein Journal of Organic Chemistry, 2011
Thomas J. J. Müller
doaj   +4 more sources

Multicomponent Reactions [PDF]

open access: yesMolecules, 2019
Multicomponent Reactions appear to be ideal for any form of synthesis, because of their numerous advantages in terms of sustainability and selectivity in building up complex molecular architectures, with high molecular diversity.
Cristina Cimarelli
doaj   +3 more sources

Multicomponent Reactions between Heteroatom Compounds and Unsaturated Compounds in Radical Reactions [PDF]

open access: yesMolecules, 2023
In this mini-review, we present our concepts for designing multicomponent reactions with reference to a series of sequential radical reactions that we have developed.
Akiya Ogawa, Yuki Yamamoto
doaj   +2 more sources

Accelerating Drug Discovery: Synthesis of Complex Chemotypes via Multicomponent Reactions. [PDF]

open access: yesACS Med Chem Lett, 2023
The generation of multiple bonds in one reaction step has attracted massive interest in drug discovery and development. Multicomponent reactions (MCRs) offer the advantage of combining three or more reagents in a one-pot fashion to effectively yield a ...
Buskes MJ   +4 more
europepmc   +2 more sources

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