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Consecutive multicomponent reactions for the synthesis of complex molecules.

Organic and biomolecular chemistry, 2019
Multicomponent reactions (MCRs) involving a minimum of three reactants or reaction centers are conducted in one pot and with a single operational step. This synthetic method has a good pot, atom and step economy in the preparation of diverse and complex ...
Sanjun Zhi, Xiaoming Ma, Wei Zhang
semanticscholar   +1 more source

Synthesis of Lactams via Isocyanide-Based Multicomponent Reactions

Synthesis, 2020
Lactams are very important heterocycles as a result of their presence in a wide range of bioactive molecules, natural products and drugs, and also due their utility as versatile synthetic intermediates. Due to these reasons, numerous efforts have focused
S. Pharande
semanticscholar   +1 more source

Multicomponent reactions for the synthesis of pyrroles

Chemical Society Reviews, 2010
Multicomponent reactions are one of the most interesting concepts in modern synthetic chemistry and, as shown in this critical review, they provide an attractive entry into pyrrole derivatives, which are very important heterocycles from many points of view including medicinal and pharmaceutical chemistry and materials science (97 references).
Verónica, Estévez   +2 more
openaire   +2 more sources

Multicomponent Reactions of Convertible Isonitriles

The Journal of Organic Chemistry, 2009
A new family of unsaturated isonitriles has been prepared by the base-promoted ring-opening of oxazoles, offering an alternative to the conventional formamide dehydration route. These compounds undergo the full complement of multicomponent reactions for which isonitriles are known and offer the desirable trait of giving amide products that readily ...
Michael C, Pirrung   +2 more
openaire   +2 more sources

Multicomponent Reactions for Surface Modification

Macromolecular Rapid Communications, 2018
AbstractModification of material surfaces with polymers is an effective method to develop applicable polymer–material composites. Recently, multicomponent reactions (MCRs) have found their roles in advanced polymer chemistry and applied in surface modification.
Haibo Wu, Yanzi Gou, Jun Wang, Lei Tao
openaire   +2 more sources

Multicomponent Reactions Are Accelerated in Water

Journal of the American Chemical Society, 2003
Two multicomponent reactions, the Ugi and Passerini reactions, are accelerated by the use of aqueous solutions. The rate enhancements compared to those by organic solvents can approach 300-fold. Reactions performed in water offer another advantage that products are often insoluble, permitting direct isolation by precipitation.
Michael C, Pirrung, Koushik Das, Sarma
openaire   +2 more sources

Multicomponent Reactions in Polymer Synthesis

Angewandte Chemie International Edition, 2013
More participants, yet efficient reactions: Multicomponent reactions (MCRs) have found application in polymer chemistry both in the synthesis of multifunctional monomers and in post-polymerization modification. Examples include the Passerini three-component reaction, the Ugi four-component reaction, and the copper-catalyzed MCR.
openaire   +2 more sources

Heterogenous green catalysis: Application of zeolites on multicomponent reactions

Current Opinion in Green and Sustainable Chemistry, 2019
Multicomponent reactions are processes in which three or more reactants are introduced concurrently to deliver a single product that contains the essential parts of the starting materials, and those have emerged in the last few years as an important tool
Carolina G. S. Lima   +3 more
semanticscholar   +1 more source

Organocatalytic Asymmetric Multicomponent Reactions

2015
A review. This review outlines the applications of organocatalysis for the improvement of asym. multicomponent reactions. Addnl., applications of organocatalytic asym. multicomponent reactions in the total synthesis of both natural products and their analogs having notorious pharmaceutical and medicinal employment as well as biocidal activities has ...
Gasperi, Tecla   +3 more
openaire   +2 more sources

Multicomponent Reactions-Based Modified/Functionalized Materials in the Biomedical Platforms.

ACS Applied Bio Materials, 2019
In various physiological and biological functions, bioactive materials as a key technique or procedure hold promise for the achievement of therapeutic effects in animals or humans.
Siamak Javanbakht, A. Shaabani
semanticscholar   +1 more source

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