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Recent Advances in Multicomponent Reactions with Organic and Inorganic Sulfur Compounds
The chemical record, 2021In recent years, multicomponent reactions with inorganic and organic sulfur compounds as one of reactants have achieved a remarkable development. In this review, we summarize recent advances in the multicomponent reactions involving sulfur components ...
Qinqin Tang +3 more
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Multicomponent Reactions of Cyclobutanones
The Journal of Organic Chemistry, 2009Cyclobutanones are essentially unknown as reactants in isonitrile-based multicomponent reactions. Ugi reactions of cyclobutanone and Passerini reactions of tetramethylcyclobutane-1,3-dione have been performed in this work. These reactions are significantly enhanced by being conducted in water, a subject of recent interest whose basis is still in ...
Michael C, Pirrung, Jianmei, Wang
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The Gewald multicomponent reaction
Molecular Diversity, 2010The Gewald reaction of sulfur, cyanoacetic acid derivatives, and oxo-component (G-3CR) yielding highly substituted 2-aminothiophene derivatives has seen diverse applications in combinatorial and medicinal chemistry. Its products are of great use in pharmaceutical industry mainly as small molecular weight inhibitors. We herein review synthetic scope and
Yijun, Huang, Alexander, Dömling
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Desosamine in multicomponent reactions
Bioorganic & Medicinal Chemistry Letters, 2006Desosamine occurring ubiquitously in natural products is introduced into isocyanide based multicomponent reaction chemistry. Corresponding products are of potential interest for the design of novel antibiotics.
Achatz, Sepp, Dömling, Alexander
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Multicomponent reactions (MCR) in medicinal chemistry: a patent review (2010-2020)
Expert Opinion on Therapeutic Patents, 2020Introduction: Multicomponent reactions (MCR) has been utilized to synthesize a vast range of analogs belonging to diverse classes of heterocyclic compounds offering multidimensional pharmaceutical applications.
Hafiza Amna Younus +6 more
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ChemInform, 2004
AbstractFor Abstract see ChemInform Abstract in Full Text.
Arounarith Tuch, Stefan Walle
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AbstractFor Abstract see ChemInform Abstract in Full Text.
Arounarith Tuch, Stefan Walle
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Employing Multicomponent Reactions in Heterocycle Synthesis: Recent Advances
Annalen der PharmacieMulticomponent reactions (MCRs) have paved their way as highly reliable tool in contemporary chemistry, serving not only as an atom economic version but also as an efficient one‐pot protocol in the synthesis of various pharmaceutically relevant ...
Tapas Ghosh +3 more
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Accounts of Chemical Research
ConspectusIn recent years, radical-mediated cross-coupling reactions have emerged as a compelling strategy for achieving a rich diversity in molecular topologies under benign conditions.
Peng-Zi Wang +3 more
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ConspectusIn recent years, radical-mediated cross-coupling reactions have emerged as a compelling strategy for achieving a rich diversity in molecular topologies under benign conditions.
Peng-Zi Wang +3 more
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Organic and biomolecular chemistry, 2020
One-pot multiple bond-forming reactions under metal-free conditions have tremendous potential in organic and medicinal chemistry considering their synthetic efficiency and eco-friendliness. In this direction, organocatalysis, i.e.
Tasneem Parvin +2 more
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One-pot multiple bond-forming reactions under metal-free conditions have tremendous potential in organic and medicinal chemistry considering their synthetic efficiency and eco-friendliness. In this direction, organocatalysis, i.e.
Tasneem Parvin +2 more
semanticscholar +1 more source
Metal–organic frameworks: advanced tools for multicomponent reactions
Green Chemistry, 2020Metal–organic frameworks (MOFs) offering abundant catalytic sites in highly ordered crystalline skeletons have recently received considerable attention as green platforms for multicomponent reactions, which are discussed in this review.
M. Ghasemzadeh +3 more
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