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Multicomponent Reactions for the Synthesis of Bioactive Compounds: A Review
Current Organic Synthesis, 2019Multicomponent reactions (MCRs) are composed of three or more reagents in which the final product has all or most of the carbon atoms from its starting materials.
Cedric S Graebin +2 more
exaly +2 more sources
Integrating biocatalysis and multicomponent reactions
Drug Discovery Today: Technologies, 2018 While often multicomponent reactions (MCR) are used for the diversity-oriented synthesis of racemic (or achiral) molecular entities, this short review describes two alternative approaches for accessing enantiopure products exploiting the power of biocatalysis.
LAMBRUSCHINI, CHIARA +2 more
openaire +3 more sources
Multicomponent Reactions for the Synthesis of Heterocycles
Chemistry - an Asian Journal, 2010AbstractMulticomponent domino reactions (MDRs) serve as a rapid and efficient tool for the synthesis of versatile heterocycles, particularly those containing structural diversity and complexity, by a one‐pot operation. These reactions can dramatically reduce the generation of chemical wastes, costs of starting materials, and the use of energy and ...
Trideep Rajale +2 more
exaly +3 more sources
Heterogeneous Catalysis in Sustainable Synthesis, 2022
B. Török, C. Schäfer, Anne Kokel
semanticscholar +3 more sources
B. Török, C. Schäfer, Anne Kokel
semanticscholar +3 more sources
Journal of the American Chemical Society, 2023
Multicomponent reactions (MCRs) can be used to introduce different functionalities into highly stable covalent organic frameworks (COFs). In this work, the irreversible three-component Doebner reaction is utilized to synthesize four chemically stable ...
Prasenjit Das +5 more
semanticscholar +1 more source
Multicomponent reactions (MCRs) can be used to introduce different functionalities into highly stable covalent organic frameworks (COFs). In this work, the irreversible three-component Doebner reaction is utilized to synthesize four chemically stable ...
Prasenjit Das +5 more
semanticscholar +1 more source
Construction of Covalent Organic Frameworks via Multicomponent Reactions.
Journal of the American Chemical Society, 2023Multicomponent reactions (MCRs) combine at least three reactants to afford the desired product in a highly atom-economic way and are therefore viewed as efficient one-pot combinatorial synthesis tools allowing one to significantly boost molecular ...
Qun Guan, Le‐Le Zhou, Yu‐Bin Dong
semanticscholar +1 more source
Enantioselective Synthesis of Azahelicenes through Organocatalyzed Multicomponent Reactions.
Angewandte Chemie, 2023We have developed an efficient modular asymmetric synthesis of azahelicenes through an organocatalyzed asymmetric multicomponent reaction from readily available polycyclic aromatic amines, aldehydes, and (di)enamides, by employing a central-to-helical ...
Wei Liu +5 more
semanticscholar +1 more source
Dimensional Reduction of Lewis Acidic Metal-Organic Frameworks for Multicomponent Reactions.
Journal of the American Chemical Society, 2021Owing to hindered diffusions, the application of porous catalytic materials has been limited to relatively simple organic transformations with small substrates.
Xuanyu Feng, Yang Song, Wenbin Lin
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How and Why to Investigate Multicomponent Reactions Mechanisms? A Critical Review
The chemical record, 2021We review the most innovative efforts and greatest challenges faced when elucidating multicomponent reactions (MCRs) mechanisms. When compared to traditional reactions, the often two or more concurrent reactions pathways and the greater number of ...
M. O. Rodrigues, M. Eberlin, B. A. Neto
semanticscholar +1 more source
New Journal of Chemistry, 2021
This review describes the evolution and application of active metal-based and heterometallic NPs as efficient heterogeneous catalysts for the synthesis of pyridine derivatives by multicomponent reactions in the last decade (2010–2020).
Fatemeh Majidi Arlan +3 more
semanticscholar +1 more source
This review describes the evolution and application of active metal-based and heterometallic NPs as efficient heterogeneous catalysts for the synthesis of pyridine derivatives by multicomponent reactions in the last decade (2010–2020).
Fatemeh Majidi Arlan +3 more
semanticscholar +1 more source