Results 231 to 240 of about 76,878 (276)

1,2‐Diazetidines − Structure, Synthesis, and Functionalization

European Journal of Organic Chemistry, EarlyView.
1,2‐Diazetidines are saturated four‐membered heterocycles featuring two adjacent nitrogen atoms. Despite recent advances in their synthesis and promising potential in medicinal chemistry, the chemistry of these cyclic hydrazines remains underexplored.
Stefan Roesner
wiley   +1 more source

Nickel‐Catalyzed Three‐Component Coupling Reactions of Iodobenzenes, an Isocyanide, and a Disilathiane: Access to Cyclic Thioimidates and Secondary Thioamides

European Journal of Organic Chemistry, EarlyView.
The one‐pot synthesis of 3‐benzylidenbenzo[c]thiophen‐1‐amines was achieved through the nickel‐catalyzed three‐component coupling reaction of 1‐ethynyl‐2‐iodobenzenes, tert‐butyl isocyanide, and hexamethyldisilathiane. This procedure is applicable to the preparation of secondary thioamides using aryl iodides.
Norio Sakai, Shun Nishitai, Reo Ikeda, Yohei Ogiwara, Kento Ishida   +4 more
wiley   +1 more source

Sustainable Microwave‐Enhanced Synthesis of 2‐Substituted Benzofurans From o‐Alkynylanisoles in Acidic Deep Eutectic Solvents

European Journal of Organic Chemistry, EarlyView.
A microwave‐enhanced sustainable and versatile approach to substituted benzofurans from 2‐alkynylanisoles enabled by an active Brønsted acidic deep eutectic solvent. The research on alternative media for organic transformations remains a highly demanding topic.
Alessandra Gritti, Angelica Sita, Mehri Goudarzi, Stefano Fedeli, Elison Lepore, Donatella Nava, Matteo Tiecco, Alessandro Caselli, Valentina Pirovano, Giorgio Abbiati   +9 more
wiley   +1 more source

Multicomponent Reactions

, 2009
openaire   +1 more source

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Photoinduced Multicomponent Reactions

Angewandte Chemie International Edition, 2016
AbstractThe combination of multicomponent approaches with light‐driven processes opens up new scenarios in the area of synthetic organic chemistry, where the need for sustainable, atom‐ and energy‐efficient reactions is increasingly urgent. Photoinduced multicomponent reactions are still in their infancy, but significant developments in this area are ...
GARBARINO, SILVIA, Ravelli, Davide, Protti, Stefano, BASSO, ANDREA   +3 more
openaire   +5 more sources

Multicomponent Reactions with Isocyanides

Angewandte Chemie, 2000
Multicomponent reactions (MCRs) are fundamentally different from two-component reactions in several aspects. Among the MCRs, those with isocyanides have developed into popular organic-chemical reactions in the pharmaceutical industry for the preparation of compound libraries of low-molecular druglike compounds.
, Dömling, , Ugi
openaire   +4 more sources

Small Heterocycles in Multicomponent Reactions

Chemical Reviews, 2014
Benjamin H, Rotstein, Serge, Zaretsky, Vishal, Rai, Andrei K, Yudin   +3 more
openaire   +4 more sources

Multicomponent Reactions

ChemInform, 2004
AbstractFor Abstract see ChemInform Abstract in Full Text.
Arounarith Tuch, Stefan Walle
openaire   +1 more source

The Gewald multicomponent reaction

Molecular Diversity, 2010
The Gewald reaction of sulfur, cyanoacetic acid derivatives, and oxo-component (G-3CR) yielding highly substituted 2-aminothiophene derivatives has seen diverse applications in combinatorial and medicinal chemistry. Its products are of great use in pharmaceutical industry mainly as small molecular weight inhibitors. We herein review synthetic scope and
Yijun, Huang, Alexander, Dömling
openaire   +2 more sources

Multicomponent Reactions of Cyclobutanones

The Journal of Organic Chemistry, 2009
Cyclobutanones are essentially unknown as reactants in isonitrile-based multicomponent reactions. Ugi reactions of cyclobutanone and Passerini reactions of tetramethylcyclobutane-1,3-dione have been performed in this work. These reactions are significantly enhanced by being conducted in water, a subject of recent interest whose basis is still in ...
Michael C, Pirrung, Jianmei, Wang
openaire   +2 more sources