Results 221 to 230 of about 1,227,058 (270)

Theranostic Potential of an NAD(P)H‐Activatable Fluorophore: Assessing Cancer Aggressiveness and Triggering Apoptosis

open access: yesAngewandte Chemie, EarlyView.
DE‐CQ, an NAD(P)H‐activatable theranostic probe, enables the quantification of cancer aggressiveness via glucose‐stimulated fluorescence imaging and selectively induces apoptosis. Its multifaceted efficacy is demonstrated across 2D cells, 3D spheroids, and in vivo models.
Yujin Cha   +11 more
wiley   +1 more source

From Berzelius to Hyperspace: Previously Unrecognized Network of Reactivity in Textbook Brominations

open access: yesAngewandte Chemie, EarlyView.
Robotic scans across multidimensional condition spaces of classic bromination reactions uncover regions of previously unrecognized reactivity, yielding new major products and novel substitution patterns. Correlation and anticorrelation analyses of product distributions across these hyperspaces enable reconstruction of the underlying mechanistic ...
Yankai Jia   +9 more
wiley   +1 more source

Rerouting Oxygen Evolution Through Interfacial Carbonate Chemistry in Near‐Neutral Seawater Electrolysis

open access: yesAngewandte Chemie, EarlyView.
Carbonate species play a previously overlooked role in near‐neutral seawater electrocatalysis. By coupling electrochemical hydrodynamics with mesoscopic simulations, we reveal a plausible carbonate‐mediated route in which carbonate functions as an interfacial proton acceptor and water as the oxygen donor, showing a possible mechanistic picture of ...
Miao Wang   +2 more
wiley   +1 more source

Modular Access to α‐Tertiary Amines: Electrochemical Tandem Di‐Functionalization of Olefins With Ammonia Surrogates and Amino Acids

open access: yesAngewandte Chemie, EarlyView.
A metal‐ and oxidant‐free electrochemical multicomponent di‐functionalization strategy that rapidly converts 1,1‐disubstituted alkenes into α‐tertiary primary amines with simultaneous installation of bio‐relevant sulfur or selenium motifs was devised for late‐stage functionalization. ABSTRACT Quaternary carbon centers, especially those bearing nitrogen,
Adrija Ghosh   +4 more
wiley   +1 more source

Created Ex Nihilo: A Near‐Infrared Afterglow Luminescent Framework of Imidazole Derivatives for Bioimaging

open access: yesAngewandte Chemie, EarlyView.
A series of Ir(III) complexes (Ir‐1‐Ir‐4) based on imidazole derivatives provide a new afterglow luminescence mechanism. The work expands the range of afterglow luminescence frameworks to overcome: (i) a lack of new afterglow scaffolds; (ii) the dependence on initial external light activation; and (iii) aggregation‐caused quenching.
Zihan Wu   +9 more
wiley   +1 more source

Photoinduced Multicomponent Reactions

open access: yesAngewandte Chemie - International Edition, 2016
The combination of multicomponent approaches with light-driven processes opens up new scenarios in the area of synthetic organic chemistry, where the need for sustainable, atom- and energy-efficient reactions is increasingly urgent.
Andrea Basso   +2 more
exaly   +5 more sources

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