Results 51 to 60 of about 1,227,058 (270)

Synthesis of (macro)heterocycles by consecutive/repetitive isocyanide-based multicomponent reactions

Beilstein Journal of Organic Chemistry, 2019
Isocyanide-based multicomponent reactions are a versatile tool in the synthesis of heterocycles. This review describes recently developed approaches based on the combination of consecutive or repetitive isocyanide-based multicomponent reactions for the ...
Angélica de Fátima S. Barreto, Carlos Kleber Z. Andrade   +1 more
doaj   +1 more source

Efficiency Efficiency, Diversity, and Complexity with Multicomponent Reactions Efficiency Efficiency, Diversity, and Complexity with Multicomponent Reactions

, 2013
Multicomponent reactions (MCRs) are versatile syntheses for obtaining structurally diverse sets of complex scaffolds with high efficiency. As such, they can be attractive synthetic tools for the realization of diversity- and/or biology-oriented synthesis
Ruijter, E.; id_orcid, Orru, R.V.A., Ruijter, E., Orru, R.V.A.; id_orcid, van der Heijden, G.   +4 more
core   +1 more source

Non‐Additive Criteria Assessment in Sustainability Evaluation of High Entropy Alloys: A Toxicity‐Weighted Framework

Advanced Engineering Materials, EarlyView.
Sustainability assessment requires methodologies that appropriately distinguish between additive and non‐additive material properties. A toxicity‐weighted scoring system is developed and applied that accounts for the disproportionate influence of highly toxic constituents through nonlinear weighting functions, providing more realistic estimates than ...
Seth Mehalic, Oladele A. Ogunseitan, Julie M. Schoenung   +2 more
wiley   +1 more source

Enantioselective Ugi and Ugi-azide reactions catalyzed by anionic stereogenic-at-cobalt(III) complexes

Nature Communications, 2022
Ugi reactions are well known multicomponent reactions that allow the preparation of a variety of chemical compounds including peptides, heterocyclic compounds, or natural products.
Bing-Bing Sun, Kun Liu, Quan Gao, Wei Fang, Shuang Lu, Chun-Ru Wang, Chuan-Zhi Yao, Hai-Qun Cao, Jie Yu   +8 more
doaj   +1 more source

Entropy‐Driven Design of Low‐Melting‐Point Alloys via Compositionally Complex Strategy

Advanced Engineering Materials, EarlyView.
Conventional low‐melting‐point alloys (LMPAs) are limited by a narrow compositional space and inherent property trade‐offs. This review presents an entropy‐driven design strategy that overcomes these limitations, ushering in a new class of low‐melting‐point compositionally complex alloys (LMCCAs).
Yinghui Shang, Jianxiang Zhao, Zhaoqi Chen, Hao Gong, Yinsen Yan, Junlei Tao, Yong Yang   +6 more
wiley   +1 more source

High‐Entropy Alloy Interlayers Toward Advanced Joining for High‐Performance Structural Applications: Current Progress and Emerging Challenges

Advanced Engineering Materials, EarlyView.
HEA interlayers offer a versatile route for joining high‐performance structural materials. Their compositional and structural design regulates interfacial reactions, suppresses brittle IMCs, and improves metallurgical bonding. Sandwich interlayers further integrate defect healing with precipitation strengthening, enabling improved strength–ductility ...
Lin Yuan, Jiafen Song, Jinglong Li, Jiangtao Xiong, Tao Yang   +4 more
wiley   +1 more source

Multicomponent reactions - opportunities for the pharmaceutical industry

, 2013
Multicomponent reactions - reactions that combine three or more starting materials in one pot to give a single product that contains essentially all of the atoms of the reactants - offer many exciting opportunities for medicinal chemistry.
Ruijter, Eelco; id_orcid, Ruijter, Eelco, Orru, Romano V A; id_orcid, Orru, Romano V A   +3 more
core   +1 more source

3D Bioprinted Glioblastoma Multiforme Models: How the Extracellular Matrix Glycosignature Influences Drug Response

Advanced Functional Materials, EarlyView.
Aberrant glycosylation in the glioblastoma tumor microenvironment drives therapeutic resistance. Here, a 3D bioprinted model was engineered by incorporating α‐NeuNAc‐(2→3)‐β‐D‐Gal‐ and chondroitin sulfate. Combined multiplex immunofluorescence and synchrotron‐based nanoCT analysis revealed that glycan‐matrix interactions dictate specific drug‐escape ...
Francesca Cadamuro, Marco Piazzoni, Ilaria Borghi, Alberto Baeri, Alessandro Fumagalli, Federica Perillo, Hafiz Muhammad Fahad, Martina Ghizzi, Luca Crippa, Gabriella Nicolini, Angela Bentivegna, Daniele Ramazzotti, Valentina Zuliani, Mirko Rivara, Carlo Giorgio Giussani, Andrea Di Cristofori, Guido Cavaletti, Federica Facciotti, Sobhan Sheikhi, Claire Seydoux, Murielle Salome, Peter Cloetens, Alberto Bravin, Paola Coan, Francesco Nicotra, Laura Russo   +25 more
wiley   +1 more source

Reconstructing Residual‐Solvent‐Involved Li+ Coordination in PVDF‐HFP Polymer Electrolytes for Stable Lithium Metal Batteries

Advanced Functional Materials, EarlyView.
2,2,2‐trifluoroethanamide‐mediated coordination regulation reconstructs the local Li+ environment in PVDF‐HFP polymer electrolytes by weakening residual DMF‐dominated coordination and promoting TFSI−‐involved anion‐rich solvation. This strategy facilitates Li+ migration and interfacial desolvation, promotes the formation of a thin inorganic‐rich SEI ...
Xiangsong Jiang, Qi Liu, Haohan Chen, Jianwei Lu, Yupeng Feng, Youwei Wang, Tianhao Zhao, Na Jiang, Wei Yang, Fei Li, Chunwei Dong, Shubiao Xia, Zhenzhen Shen, Weiwei Lei, Dan Liu, Jianping Long, Shimou Chen, Anjun Hu   +17 more
wiley   +1 more source

Atom- and step-economic synthesis of biaryl-substituted furocoumarins, furoquinolones and furopyrimidines by multicomponent reactions and one-pot synthesis

Green Processing and Synthesis, 2013
Atom-efficient multicomponent reactions (MCR) and step-efficient one-pot synthesis are developed for the synthesis of biaryl-substituted furocoumarins, furoquinolones, and furopyrimidines.
Kadam Asha, Bellinger Stephanie, Zhang Wei   +2 more
doaj   +1 more source