Inhibition of CDK9 sensitizes multidrug resistant ovarian cancer cells to paclitaxel. [PDF]
Wang J +4 more
europepmc +1 more source
Antimicrobial Cyclic Peptidomimetics
Singular macromolecular cationic, amphipathic cyclic peptidomimetics with poly(2‐oxazoline)s‐esque backbone structure that undergo self‐assembly in water to form uniform nanoparticles were developed. The cyclic peptidomimetics, which act on bacterial cell membranes, exhibit hydrophobic‐dependent antimicrobial activity and toxicity.
Hao Luo, Edgar H. H. Wong
wiley +1 more source
Selenium-Based Strategies for Targeting Multidrug-Resistant Breast Cancer: A Review. [PDF]
Bajer H +3 more
europepmc +1 more source
Cefdinir reprograms Gram‐positive bacteria to synergize with lysozyme against superbugs
Abstract Multidrug‐resistant (MDR) bacteria pose a critical global health threat, urgently requiring solutions. Cefdinir, the highest‐selling third‐generation cephalosporin but one now facing clinical obsolescence due to escalating resistance, is conventionally classified as a nascent cell wall synthesis inhibitor.
Qi Zhang +6 more
wiley +1 more source
Advances in phytochemical-derived nanotherapeutics for multimodal eradication of multidrug-resistant <i>Staphylococcus aureus</i>. [PDF]
Gupta N +9 more
europepmc +1 more source
Rapid and quantitative phage susceptibility test by ramanome
Abstract Antimicrobial resistance poses an escalating global threat, renewing interest in bacteriophage therapy as a precision alternative to antibiotics. However, clinical translation remains hindered by the lack of rapid and quantitative phage susceptibility testing (PST) platforms capable of evaluating host range, infection potency, and effective ...
Xiao Han +10 more
wiley +1 more source
Drug repurposing to combat multidrug-resistant hookworm. [PDF]
McKean EL +4 more
europepmc +1 more source
Current Cell/Organoid and Animal Models for Primary Sclerosing Cholangitis
Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease with limited therapeutic options and a marked risk of progression to biliary fibrosis, cirrhosis, and malignancy. Progress in PSC research has been hindered by the lack of models that faithfully recapitulate the complex biliary microenvironment and disease heterogeneity ...
Qigu Yao +4 more
wiley +1 more source
Multidrug Resistant Salmonella enterica serovartyphi
D Acharya +3 more
doaj +1 more source
Plant extracts: a potential approach to combating multidrug-resistant bacteria. [PDF]
Kong SS, Park CH.
europepmc +1 more source

