Results 161 to 170 of about 181,836 (261)

Antimicrobial Cyclic Peptidomimetics

open access: yesMacromolecular Rapid Communications, EarlyView.
Singular macromolecular cationic, amphipathic cyclic peptidomimetics with poly(2‐oxazoline)s‐esque backbone structure that undergo self‐assembly in water to form uniform nanoparticles were developed. The cyclic peptidomimetics, which act on bacterial cell membranes, exhibit hydrophobic‐dependent antimicrobial activity and toxicity.
Hao Luo, Edgar H. H. Wong
wiley   +1 more source

Cefdinir reprograms Gram‐positive bacteria to synergize with lysozyme against superbugs

open access: yesmLife, EarlyView.
Abstract Multidrug‐resistant (MDR) bacteria pose a critical global health threat, urgently requiring solutions. Cefdinir, the highest‐selling third‐generation cephalosporin but one now facing clinical obsolescence due to escalating resistance, is conventionally classified as a nascent cell wall synthesis inhibitor.
Qi Zhang   +6 more
wiley   +1 more source

Advances in phytochemical-derived nanotherapeutics for multimodal eradication of multidrug-resistant <i>Staphylococcus aureus</i>. [PDF]

open access: yesFront Pharmacol
Gupta N   +9 more
europepmc   +1 more source

Rapid and quantitative phage susceptibility test by ramanome

open access: yesmLife, EarlyView.
Abstract Antimicrobial resistance poses an escalating global threat, renewing interest in bacteriophage therapy as a precision alternative to antibiotics. However, clinical translation remains hindered by the lack of rapid and quantitative phage susceptibility testing (PST) platforms capable of evaluating host range, infection potency, and effective ...
Xiao Han   +10 more
wiley   +1 more source

Drug repurposing to combat multidrug-resistant hookworm. [PDF]

open access: yesBiol Open
McKean EL   +4 more
europepmc   +1 more source

Current Cell/Organoid and Animal Models for Primary Sclerosing Cholangitis

open access: yesPortal Hypertension &Cirrhosis, EarlyView.
Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease with limited therapeutic options and a marked risk of progression to biliary fibrosis, cirrhosis, and malignancy. Progress in PSC research has been hindered by the lack of models that faithfully recapitulate the complex biliary microenvironment and disease heterogeneity ...
Qigu Yao   +4 more
wiley   +1 more source

Multidrug Resistant Salmonella enterica serovartyphi

open access: yesJournal of Nepal Medical Association, 2009
D Acharya   +3 more
doaj   +1 more source

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