Results 181 to 190 of about 181,836 (261)

Large‐Scale Structural Dynamics in the Tail Fiber Modulate the Infective Transition of the T7 Bacteriophage

open access: yesSmall, EarlyView.
During host recognition, the fibers of T7 bacteriophages transition from a capsid bound state to an extended conformation, which requires some level of fiber flexibility. By using high‐speed atomic force microscopy, we show that the fibers have an internal molecular hinge and a torsionally compliant coiled‐coil region.
Luca Elizabet Kosik   +16 more
wiley   +1 more source

Multidrug-Resistant Pathogen Clonal Spread in Nigeria: A Systematic Review and Meta-Analysis. [PDF]

open access: yesHealth Sci Rep
Ugbo EN   +5 more
europepmc   +1 more source

Multifunctional Nanodiamond Conjugate With a Tumor‐Specific EGFR‐Targeting Peptide and Photoactivated CO Release for Improved Therapeutic Efficacy in Head and Neck Cancers

open access: yesSmall, EarlyView.
A multifunctional nanodiamond conjugate carrying a blue light‐activated carbon monoxide‐releasing molecule and an EGFR‐targeting peptide enables efficient, targeted CO delivery in vitro and in vivo. Upon photoactivation, the particles induce cancer‐specific cytotoxicity and significantly suppress tumor growth and lymph node metastasis in a head and ...
Harsh Nitin Dongre   +12 more
wiley   +1 more source

Unraveling the Physicochemical Landscape of Organoselenium Compounds in Nanocarrier Systems

open access: yesThe Chemical Record, EarlyView.
Main nanocarriers employed to enhance the bioavailability and transport of organoselenium compounds. The image illustrates the key interaction forces that stabilize these organoselenium species in solution, enabling their application in drug delivery systems, catalysis, photoelectronic devices, and sensing technologies. In recent years, publications on
Romelly Eugenia Rojas Ramírez   +3 more
wiley   +1 more source

Printing to Fight Antimicrobial Resistance Through Nano/Microstructured Platforms

open access: yesThe Chemical Record, EarlyView.
Additive manufacturing enables the rational design of structured antimicrobial platforms across multiple length scales, from nanofibrous scaffolds and droplet microreactors to 3D and 4D printed constructs. By engineering confinement, interfacial chemistry, and stimuli‐responsive release, these systems exert localized action through complementary ...
Giorgia Puleo   +11 more
wiley   +1 more source

Diving Deeper Into Mechanisms of Acrylamide‐Induced Toxicity: RNA Sequencing Reveals Transcriptomic Alteration and Retrotransposon Expression in Drosophila melanogaster

open access: yesEnvironmental Toxicology, EarlyView.
ABSTRACT Given the inevitability of human and animal exposure to acrylamide, there is increasing concern regarding its potential health risks. While a number of molecular mechanisms have been proposed, the complexity of acrylamide toxicological pathways and interactions remains incompletely characterized.
Oluwabukola Mary Farodoye   +5 more
wiley   +1 more source

Harnessing random peptide mixtures to combat multidrug-resistant fungal infections. [PDF]

open access: yesmBio
Adeoye J   +6 more
europepmc   +1 more source

Cystitis in guinea pigs (Cavia porcellus): Clinical findings and treatment outcomes

open access: yesVeterinary Record, EarlyView.
Abstract Background This retrospective study examined the incidence, diagnostic methods, bacterial isolates, treatments and outcomes associated with cystitis in guinea pigs presented at a single clinic between 2009 and 2022. Methods The clinic's medical records database was reviewed using easyvet software to identify cases eligible for inclusion in the
Anika Mische, Kerstin Müller
wiley   +1 more source

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