Results 181 to 190 of about 306,632 (271)

Plasma metabolomic signatures in patients with multidrug-resistant bacterial sepsis. [PDF]

Metabolomics
Wang J, Luo G, Lv P, Li Q, Yu S, Chen Y, Yu L, Li K.   +7 more
europepmc   +1 more source

Potent monoclonal antibodies against multidrug‐resistant hypervirulent Klebsiella pneumoniae

Interdisciplinary Medicine, EarlyView.
A novel immunization strategy using a low‐virulence, multidrug‐resistant strain yields synergistic monoclonal antibodies against hypervirulent Klebsiella pneumoniae. These antibodies provide cross‐serotype protection through a dual‐mechanism of pathogen clearance and immunomodulation, offering a promising non‐antibiotic therapeutic for resistant ...
Yushan Jiang, Zhuolin Li, Yang Yang, Zihan He, Tyuji Hoshino, Vladislav Victorovich Khrustalev, Qing Zhu, Weiling Wu, Wei Zhao, Chenguang Shen, Shi Ouyang   +10 more
wiley   +1 more source

Migratory Birds Facilitate the Spread of Multidrug-Resistant Pathogenic Escherichia coli in Tanguar Haor of Bangladesh. [PDF]

Environ Microbiol Rep
Khatun MN, Chakraborty S, Akter T, Ifte JS, Begum JA, Islam MA, Parvin R, Hossain MT, Chowdhury EH.   +8 more
europepmc   +1 more source

SUMOylation regulates tumorigenesis and progression: Molecular mechanisms and therapeutic applications

Interdisciplinary Medicine, EarlyView.
SUMOylation, a dynamic post‐translational modification, acts as a master regulator at the heart of tumor malignancy. Our work delineates how the SUMOylation cycle—mediated by E1/E2/E3 enzymes and reversed by SENPs—orchestrates multiple hallmarks of cancer. The central pathway converges on three critical pathological axes: 1.
Yimao Wu, Zichang Chen, Yinting Hu, Gokhan Zengin, Qian Zhang, Meng‐Yao Li, Wenlong Sun   +6 more
wiley   +1 more source

Phage-antibiotic combination: a possible approach to combatting multidrug-resistant Klebsiella pneumoniae. [PDF]

AMB Express
Abdelhakim NI, Alshareef WA, Saleh SE, Yassein MA.   +3 more
europepmc   +1 more source

Evaluation of FilmArray Multiplex PCR Test Results in Bloodstream Infections in Oncological Patients

Journal of Clinical Laboratory Analysis, EarlyView.
In this study conducted at an oncology hospital, BCID2 panel results for the rapid identification of microorganisms and resistance genes in positive blood culture samples were compared with conventional culture methods. The BCID2 panel provided faster results and showed a high correlation with traditional methods.
İpek Mumcuoğlu, Sevgi Şahin, Esra Tavukcu, Neşe İnan, Ayşe Semra Güreser, Serap Süzük Yıldız, Tuba Dal   +6 more
wiley   +1 more source

Decolonizing the gut from multidrug-resistant bacteria: Current strategies and future perspectives. [PDF]

World J Methodol
Mishra A, Juneja D.
europepmc   +1 more source

Genomic Insights Into Carbapenem‐Resistant Klebsiella pneumoniae in Pediatric Bloodstream Infections in Zhejiang, China (2019–2024)

Journal of Clinical Laboratory Analysis, EarlyView.
The primary mechanism of carbapenem resistance identified in pediatric CRKP‐BSI strains was the production of Class B metalloenzymes. We report, for the first time, an outbreak of bloodstream infections in a neonatal ward caused by the dissemination of NDM‐1‐producing ST25 K. pneumoniae.
Mingming Zhou, Xiucai Zhang, Zhenjie Chen, Chao Fang, Shixing Liu, Jintao Xia, Yining Zhao, Chenmei Zhang, Hongqiang Shen   +8 more
wiley   +1 more source

Fosfomycin combination therapy in high-risk paediatric patients with multidrug-resistant infections: a retrospective study. [PDF]

Eur J Pediatr
Denina M, Badiali L, Vitale R, Robasto F, Funiciello E, Silvestro E, Pruccoli G, Garazzino S.   +7 more
europepmc   +1 more source

Automated Imaging of Cultured Bacteria in Picoliter Droplets by Coherent Anti‐Stokes Raman Scattering and Two‐Photon Excited Fluorescence Microscopy

Journal of Raman Spectroscopy, EarlyView.
We present an automated system that combines an image‐based fuzzy logic controller for precise positioning of microfluidic picoliter droplets with nonlinear microscopy, using CARS and TPEF modalities for detailed analysis of droplet composition. Time series and z‐stack images of E. coli, B. subtilis, and M. arborescens were recorded.
Fabian Ott, Ashkan Samimi, Sundar Hengoju, Tobias Meyer‐Zedler, Michael Schmitt, Miriam A. Rosenbaum, Jürgen Popp   +6 more
wiley   +1 more source