Results 201 to 210 of about 306,632 (271)

Phenotypic and Metabolic Variations in High-Risk Clones of Multidrug-Resistant <i>Pseudomonas aeruginosa</i>. [PDF]

Microorganisms
Gutierrez SJ, Escobar Prieto JD, Vargas DA, Burchmore R, Burguess K, Correa A.   +5 more
europepmc   +1 more source

Uncovering Key Characteristics of Antibacterial Peptides through Machine Learning

Macromolecular Rapid Communications, EarlyView.
Machine‐learning (ML) techniques using random forest classification models revealed key characteristics that predict effective antimicrobial peptides (AMPs) targeting Gram‐negative bacteria, Gram‐positive bacteria, and mycobacteria. The ideal cLogP (<$ < $−6) and net‐charge (≤+4) threshold was the same for all three targets with variations in the ...
Jooyoung Roh, Cyrille Boyer, Priyank V. Kumar   +2 more
wiley   +1 more source

Multidrug Resistant Salmonella enterica serovartyphi

Journal of Nepal Medical Association, 2009
D Acharya, S Malla, D R Bhattarai, Shyam Prakash Dumre   +3 more
doaj   +1 more source

Smart Integration of Structural Biology and Medicinal Chemistry to Unlock Target‐Driven Drug Discovery

Medicinal Research Reviews, EarlyView.
ABSTRACT To enhance drug discovery efforts, medicinal chemists should evaluate, filter, and utilize relevant structural information about target proteins. Acquiring and interpreting protein structures is crucial for elucidating ligand‐receptor interactions and addressing ADME‐related considerations, making it an essential aspect of medicinal chemistry.
Matteo Rossi Sebastiano, Giulia Apprato, Serena Francisco, Giuseppe Ermondi, Giulia Caron   +4 more
wiley   +1 more source

Chilean Honey as Alternative Antibacterial: In Vitro Activity Against Multidrug-Resistant Canine Bacterial Pathogens. [PDF]

Animals (Basel)
Mireles-Villanueva MV, Reyna-Fuentes JH, Vázquez-Sauceda ML, Vargas MB, Cornejo J, Neira M, Muñoz-Sánchez RA, Lapierre L.   +7 more
europepmc   +1 more source

Genome‐wide screen reveals a universal role of ATP in ciprofloxacin tolerance among genetically distinct Escherichia coli persisters

mLife, EarlyView.
Abstract Bacterial persisters show tolerance to bactericidal antibiotics and play essential roles in chronic infections; however, the general mechanisms underlying persister formation and antibiotic tolerance remain insufficiently characterized. In this study, the Escherichia coli Keio library was used to identify genes involved in ciprofloxacin ...
Zhenfang Mei, Yawen Cai, Jianfeng Huang, Kedong Zhao, Zuqin Zhang, Dandan Yu, Shiyan Lu, Zeying Lai, Thomas K. Wood, Xinmiao Fu   +9 more
wiley   +1 more source

Epidemiological burden of multidrug-resistant bacteria and carbapenemases in Northern Morocco: a one-year observational study. [PDF]

BMC Infect Dis
El Harrak K, Al Faqir I, El Ghorba EM, Amrani Souhli R, Chahid N, Arbai M, El-Hassouni M, Bousgheiri F, Najdi A, Rissoul K.   +9 more
europepmc   +1 more source

The Expanding Landscape of Microbiota Medicine: Indications, Therapeutic Modalities, and the Path Towards Integrative Microbiome‐Targeting Healthcare

Microbiota Medicine Research, EarlyView.
ABSTRACT The growing recognition of the microbiome's role in human health has propelled the emergence of microbiota medicine—a new discipline integrating microbiology, multi‐omics, and clinical science. Advances in sequencing, data integration, and interventions such as fecal microbiota transplantation (FMT) have transitioned the field from ...
Min Dai, Yisha Lin, Renyou Gan, Xiaotao Shen, Shin Young Park, Sunjae Lee, Qi Su   +6 more
wiley   +1 more source

EEG Dynamics in Children Before, During and After General Anesthesia

Pediatric Anesthesia, EarlyView.
ABSTRACT Background Age‐specific EEG signatures during anesthesia are described in pediatrics, and perioperative monitoring is increasingly advocated; yet most indices and algorithms derive from adult data and may not generalize to early development. Aims The purpose of this study was to characterize perioperative frontal EEGs in young children younger
Maximilian Markus, Feidias Panagiotou, Claudia Spies, Susanne Koch   +3 more
wiley   +1 more source

Interaction of Nanoparticles with Multidrug-Resistant Bacteria. [PDF]

ACS Omega
Singh RP, Hiteshi P, Sharma A, Kumar D, Kaur T.   +4 more
europepmc   +1 more source