Results 71 to 80 of about 80,394 (203)

Tuberculosis diagnostics and biomarkers: needs, challenges, recent advances, and opportunities [PDF]

, 2012
Tuberculosis is unique among the major infectious diseases in that it lacks accurate rapid point-of-care diagnostic tests. Failure to control the spread of tuberculosis is largely due to our inability to detect and treat all infectious cases of pulmonary
Alexandre Harari, Alimuddin Zumla, Armand, Axelsson-Robertson, Banada, Ben Marais, Betsou, Blakemore, Boehme, Boehme, Cattamanchi, Chow, Cuevas, Cuevas, Cuevas, Cuevas, Diel, Dowdy, Dye, European Centre for Disease Prevention and Control, Ferrara, Giovanni-Batista Migliori, Giuseppe Pantaleo, Green, Harari, Helb, Helen Cox, Hillemann, Hohn, Ibrahim Abubakar, Jeremiah Chakaya, John, Justin O’Grady, Karin Weyer, Keeler, Kemp, Kunnath-Velayudhan, Lawn, Lawn, Lawn, Lawn, Lawn, Lemaire, Lin, Ling, Liu, Long, Lucica Ditui, Lynn Zijenah, Mann, Marais, Marais, Marais, Marais, Marco Schito, Markus Maeurer, Marlowe, Martin P. Grobusch, Martina Casenghi, Matthew Bates, McNerney, Michael Hoelscher, Michel Pletschette, Minion, Moore, Morris, Mwaba, Nathan Ford, Nathanson, National Institute for Health and Clinical Excellence, Nicol, Nicol, Oberhelman, O’Grady, Peter, Peter Mwaba, Peter S. Kim, Rifat Atun, Rose, Ruth McNerney, S. Bertel Squire, Samana Schwank, Sester, Shah, Soumya Swaminathan, Squire, Squire, Steingart, Steingart, Steingart, Steve Lawn, Storla, Temple, Theron, Timothy D. Mchugh, Treatment Action Group, Tully, Vadwai, Van Rie, van Wyk, Wallis, Walzl, Weyer, Wilson, World Health Organization, World Health Organization, World Health Organization, World Health Organization, World Health Organization, World Health Organization, World Health Organization, World Health Organization, World Health Organization, Wright, Wright, Zar, Ziad Memish, Zumla, Zumla   +118 more
core   +2 more sources

Immune endotypes in tuberculosis: Keys to decoding disease complexity

Journal of Internal Medicine, EarlyView.
Abstract Tuberculosis (TB) remains a major global health challenge, with multi‐drug antibiotic regimens as the current standard of care. While effective at killing Mycobacterium tuberculosis, these treatments do not resolve persistent inflammation, prevent lung damage, or reverse immune dysregulation that contribute to poor outcomes and disease ...
Shamila D. Alipoor, Julia Guthrie, Lina Davies Forsman, Andrew R. Di Nardo, Susanna Brighenti   +4 more
wiley   +1 more source

Assessment of Antimicrobial Resistance in M. leprae Strains From Kiribati

Tropical Medicine &International Health, EarlyView.
ABSTRACT Objectives Kiribati has one of the highest rates of leprosy worldwide. A nationwide screening and chemoprophylaxis program for household leprosy contacts was introduced in 2018. In 2022, population‐wide screening and rifamycin‐based treatment or chemoprophylaxis for leprosy and tuberculosis was introduced as part of the PEARL and COMBINE ...
Patrick O. Campbell, Temea Bauro, Erei Rimon, Nabura Ioteba, Trevor Anderson, Arturo Cunanan, Taulanga Naniseni, Jacqui Gardner, Emma Trowbridge, Nicholas M. Douglas, Stephen T. Chambers   +10 more
wiley   +1 more source

Being safe, feeling safe, and stigmatizing attitude among primary health care staff in providing multidrug-resistant tuberculosis care in Bantul District, Yogyakarta Province, Indonesia

Human Resources for Health, 2019
Introduction Patient-centered care approach in multidrug-resistant tuberculosis care requires health worker safety that covers both being safe and feeling safe to conduct the services. Stigma has been argued as a barrier to patient-centered care. However,
Ari Probandari, Hary Sanjoto, Melani Ratih Mahanani, Luthfi Azizatunnisa, Sampir Widayati   +4 more
doaj   +1 more source

Automated Tuberculosis Detection in Chest Radiographs: A Hybrid Deep Learning Framework for Clinical Decision Support

Applied AI Letters, Volume 7, Issue 2, June 2026.
A hybrid deep learning framework integrating VGG16, ResNet50, and DenseNet121 is proposed for automated tuberculosis detection from chest X‐ray images. Feature‐level fusion enhances robustness and generalization, achieving 97.4% accuracy across multiple public datasets, supporting reliable clinical decision‐making in resource‐limited healthcare ...
Md. Tahmid Hossain, Hrittik Mural, Monowar Wadud Hridoy   +2 more
wiley   +1 more source

RESULTS OF CHEMOTHERAPY IN PATIENTS WITH MULTIDRUG-RESISTANT TUBERCULOSIS IN THE REGIONS OF THE RUSSIAN FEDERATION

Туберкулез и болезни лёгких, 2014
The paper analyzes the results of treatment in 5,396 patients with multidrug-resistant tuberculosis who were treated in the regions of the Russian Federation under the Global Fund Round 4 project based on the recommended World Health Organization ...
V. V. Testov, S. A. Sterlikov, I. A. Vasilyeva, V. V. Erokhin, T. Ch. Kesaeva   +4 more
doaj  

Drug-Resistant Tuberculosis—Current Dilemmas, Unanswered Questions, Challenges, and Priority Needs [PDF]

, 2017
Tuberculosis was declared a global emergency by the World Health Organization (WHO) in 1993. Following the declaration and the promotion in 1995 of directly observed treatment short course (DOTS), a cost-effective strategy to contain the tuberculosis ...
Abubakar, Ibrahim, Atun, Rifat, Chakaya, Jeremiah, Cox, Helen, Ditiu, Lucica, Ford, Nathan, Grobusch, Martin, Hoelscher, Michael, Lawn, Stephen D., Maeurer, Markus, Marais, Ben, Mchugh, Timothy D., McNerney, Ruth, Memish, Ziad, Migliori, Giovanni-Battista, Mwaba, Peter, O'Grady, Justin, Pletschette, Michel, Ramsay, Andrew, Raviglione, Mario, Schito, Marco, Squire, S. Bertel, Swaminathan, Soumya, Zumla, Alimuddin   +23 more
core  

Tuberculosis in prisons in sub-Saharan Africa--a potential time bomb. [PDF]

, 2011
No ...
Bates, Matthew, Kapata, Nathan, Mwaba, Peter, O'Grady, Justin, Zumla, Alimuddin   +4 more
core   +1 more source

A Case of Sepsis Caused by ST80 Multidrug‐Resistant Enterococcus faecium With Concurrent Klebsiella pneumoniae Infection in a Dog

Veterinary Medicine and Science, Volume 12, Issue 3, May 2026.
An 8‐year‐old dog developed acute respiratory distress that progressed to sepsis and death. Multidrug‐resistant Enterococcus faecium ST80 was isolated from the liver and kidney, while Klebsiella pneumoniae was detected in the lung by PCR. Whole‐genome sequencing showed that the ST80 isolates were genetically identical, suggesting hematogenous spread ...
Hyung‐min Seo, Tae‐Min La, Ye‐ram Seo, Dong‐Yeop Lee, Hyun‐Jung Han, Ji‐Yeon Hyeon   +5 more
wiley   +1 more source

Issues of Tuberculosis Drug-Resistance in Kharkiv Region and in Ukraine

Infusion & Chemotherapy, 2019
Background. Multidrug-resistant tuberculosis and extensively drug-resistant tuberculosis remain severe epidemic problems in the world. That’s why the purpose of our study was to investigate the dynamics of the incidence of multidrug-resistant and ...
O.S. Shevchenko, O.O. Pohorielova
doaj   +1 more source