Results 201 to 210 of about 234,319 (307)

Unveiling the roles of extracellular vesicles in hematologic malignancies: Pathogenesis, diagnostic tools, and clinical translation

Interdisciplinary Medicine, EarlyView.
Extracellular vesicles play pivotal roles in both healthy hematopoiesis and hematologic malignancies. They not only regulate hematopoietic stem cell fitness but also drive cancer progression and drug resistance. Their clinical potential spans from serving as non‐invasive biomarkers to acting as innovative therapeutic platforms and drug delivery ...
Fengyu Chen, Zhiyuan Wu, Feng Zhang, Yuan Meng, Hongyan Liao, Tony Y. Hu   +5 more
wiley   +1 more source

Harnessing AI for Antimicrobial Peptide Innovation against Multidrug Resistance. [PDF]

JACS Au
Pimentel JPF, Quigua Orozco RM, de Rezende SB, Lima L, Cardoso MH.   +4 more
europepmc   +1 more source

Duplex Recombinase Polymerase Amplification‐Lateral Flow Assay for Rapid Visual Detection of Critical Antibiotic Resistance Genes in Escherichia coli and Klebsiella pneumoniae From Positive Blood Cultures

Journal of Clinical Laboratory Analysis, EarlyView.
This study developed a pair of duplex RPA‐LFA assays for the simultaneous detection of critical resistance genes, blaCTX‐M/mcr‐1 and blaoxa‐48‐like/blaNDM, from hemoculture samples. Under optimized conditions, duplex RPA was performed at 37°C–38°C for 25 min, followed by LFA for 10–15 min.
Variya Nemidkanam, Pattamaporn Deechart, Nuntaree Chaichanawongsaroj   +2 more
wiley   +1 more source

Identification and phylogenetic analysis of multidrug resistance, caries-related  Streptcoccus mutans in Sulaymaniyah City, Iraqi Kurdistan Region. [PDF]

Int Microbiol
Hussein SA.
europepmc   +1 more source

Intelligent design of artificial biocatalyst for biomedical diseases

Journal of Intelligent Medicine, EarlyView.
This review summarizes recent advances in the intelligent design of artificial biocatalysts for biomedical diseases. By leveraging tailored design strategies, including environment‐responsive engineering and rational/artificial intelligence‐aided optimization, these biocatalysts enable precise modulation of pathological microenvironments and targeted ...
Lijie Zhang, Nan Song, Huanhuan Qiao, Si Sun   +3 more
wiley   +1 more source

Overcoming multidrug resistance: antimicrobial peptides as a next-generation therapeutic strategy. [PDF]

Front Cell Infect Microbiol
Zhou S, Sun Z, Liu L, Xi Y, Zhou L, Yang Z, Zhou J.   +6 more
europepmc   +1 more source

Detecting Antibiotic Resistance in Strains of Selected Gram‐Negative Bacterial Species Using Raman Spectroscopy

Journal of Raman Spectroscopy, EarlyView.
Raman spectroscopy successfully identified antibiotic‐resistant Gram‐negative strains. Resistant strains of four bacterial species were discriminated from sensitive ones with 99.1% accuracy using PLS regression. The method allows for rapid, label‐free detection of antibiotic resistance.
Fernanda Sant Ana de Siqueira e Oliveira, Adriano Moraes da Silva, Marcos Tadeu T. Pacheco, Landulfo Silveira Jr.   +3 more
wiley   +1 more source

Knockdown of CREB3L4 Inhibits Autophagy and Reduces Cisplatin Resistance in Gastric Cancer Cells by Downregulating BAG3

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Cisplatin resistance remains a major obstacle in the treatment of gastric cancer (GC), and autophagy has been increasingly recognized as a key cytoprotective mechanism contributing to chemoresistance. CREB3L4 is an endoplasmic reticulum membrane‐bound transcription factor that has been shown to regulate the expression of Bcl‐2 associated ...
Wen‐Ke Yin, Xue‐Mei Xie, Xiao‐Yan Song, Yue Xiang   +3 more
wiley   +1 more source

Bacteriological profile and multidrug resistance of Gram-negative bacteria in wound infections at a secondary healthcare facility in Ghana. [PDF]

BMC Microbiol
Agborgbor A, Abubakar L, Agyei H, Lassey G, Acheampong A, Kudzordzi PC, Nyarko P, Otabil KB.   +7 more
europepmc   +1 more source

Applications and Challenges of Artificial Intelligence in Predicting Antimicrobial Resistance

iLABMED, EarlyView.
Wenjuan Wu, Zhexiao Ma
wiley   +1 more source