Results 221 to 230 of about 235,517 (308)

Current Cell/Organoid and Animal Models for Primary Sclerosing Cholangitis

Portal Hypertension &Cirrhosis, EarlyView.
Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease with limited therapeutic options and a marked risk of progression to biliary fibrosis, cirrhosis, and malignancy. Progress in PSC research has been hindered by the lack of models that faithfully recapitulate the complex biliary microenvironment and disease heterogeneity ...
Qigu Yao, Sheng Cheng, Qiaoling Pan, Jiong Yu, Hongcui Cao   +4 more
wiley   +1 more source

Biofilm-associated antibiotic tolerance in the era of multidrug resistance: quorum-sensing mechanisms and emerging therapeutic strategies. [PDF]

Front Cell Infect Microbiol
Subramani T, George EA, Saju AE, E M, De R, K SA, Ramaiah S, Anbarasu A.   +7 more
europepmc   +1 more source

Assessing the potential for insecticide cross‐resistance to a novel insecticide in the Colorado potato beetle (Leptinotarsa decemlineata) using phenotypic and transcript expression analysis

Pest Management Science, EarlyView.
Phenotypic and transcriptional responses to imidacloprid and isocycloseram were examined across U.S. populations of the Colorado potato beetle, showing evidence of phenotypic cross‐resistance alongside population‐level variation in detoxification gene expression.
Emma E. Terris, Benjamin Z. Bradford, Faith Kulzer, Justin Clements, Kurt H. Lamour, Sean D. Schoville, Russell L. Groves   +6 more
wiley   +1 more source

Responsive nitric oxide‐releasing antibacterial materials for biofilm‐associated infections: Mechanisms, design strategies, and applications

Responsive Materials, EarlyView.
This review summarizes the recent progress in responsive NO‐releasing materials and their applications in biofilm‐associated infectious diseases. The design principles and response mechanisms are given to provide inspiration toward the future development of multi‐responsive NO‐releasing materials.
Wenyue Sun, Meiqi Li, Di Nan, Jiaqi Zhao, Yu Chen, Yao Gao, Shichen Zhang, Kirsten L. Van Landuyt, Manlin Qi   +8 more
wiley   +1 more source

Development of liposomal pemetrexed for enhanced therapy against multidrug resistance mediated by ABCC5 in breast cancer [Retraction]. [PDF]

Int J Nanomedicine
europepmc   +1 more source

Incidence and outcomes for colonization of multidrug-resistance organisms (MDROs) among patients undergoing elective orthopedic surgery. [PDF]

Antimicrob Steward Healthc Epidemiol
Umpunthongsiri S, Apisarnthanarak A, Srimanote P, Khawcharoenporn T, Aungthong C, Mungkornkaew N, Damronglerd P, Rutjanawech S, Suwantarat N.   +8 more
europepmc   +1 more source

Peptide‐based antibacterial nanoplatforms: Design principles, stimuli‐regulated behaviors, and applications

Responsive Materials, EarlyView.
Peptide‐based antibacterial nanoplatforms, encompassing self‐assembled peptides and peptide‐engineered inorganic, polymeric, and lipid nanocarriers, are systematically reviewed. The article highlights design principles and stimuli‐responsive regulation for improving peptide stability, delivery efficiency, and antibacterial performance.
Peng Tan, Chenlong Zhou, Shuaikang Yang, Zhenduo Chen, Guanghui Zhao, Qi Tang, Haoyu Yan, Feng Li, Xi Ma   +8 more
wiley   +1 more source

Factors Influencing <i>Salmonella enterica</i> Contamination and Multidrug Resistance in Pork Available at Modern Retail Stores in Urban Southern Thailand. [PDF]

Biology (Basel)
Prasertsee T, Suriyasathaporn W.
europepmc   +1 more source

Large‐Scale Structural Dynamics in the Tail Fiber Modulate the Infective Transition of the T7 Bacteriophage

Small, EarlyView.
During host recognition, the fibers of T7 bacteriophages transition from a capsid bound state to an extended conformation, which requires some level of fiber flexibility. By using high‐speed atomic force microscopy, we show that the fibers have an internal molecular hinge and a torsionally compliant coiled‐coil region.
Luca Elizabet Kosik, Miklós Cervenak, Dominik Sziklai, Andrea Balogh‐Molnár, Negar Rahimi, Bence Fehér, Soma Yamamoto, Hiroki Konno, Noriyuki Kodera, Holger Flechsig, Romain Amyot, Heinz Amenitsch, Hedvig Tordai, Levente Herényi, Ana Cuervo, Miklós Kellermayer, Bálint Kiss   +16 more
wiley   +1 more source