Results 231 to 240 of about 234,319 (307)

Overexpression of Escherichia coli yaiX Confers Multidrug Resistance and Enhances Virulence in the Silkworm Infection Model. [PDF]

Microbiol Immunol
Hongu K, Ishikawa K, Kosaki T, Miyoshi SI, Furuta K, Kaito C.   +5 more
europepmc   +1 more source

Machine Learning‐Driven Capillary Microfluidic Design Automation for Programmable Gradient Generation and Antimicrobial Testing

Small, EarlyView.
TCG‐CMDA, a machine learning‐guided capillary microfluidic design automation platform, enables automated design of tree‐shaped concentration gradient generators for programmable mixing of two agents. The pump‐free chip supports synchronized passive flow and programmable gradient formation, providing a practical framework for decentralized point‐of‐care
Mahmood Khalghollah, Azam Zare, Sorosh Abdollahi, Behrouz H. Far, Amir Sanati Nezhad   +4 more
wiley   +1 more source

Innovative Microneedle Patches for Psoriasis Treatment: A Dual Approach With Methotrexate‐Zinc and Difelikefalin for Enhanced Therapeutic Outcomes

Small, EarlyView.
This study presents a novel dual‐layer microneedle platform for psoriasis treatment, integrating rapid itch relief with sustained immunomodulatory and antibacterial effects. By combining difelikefalin and methotrexate‐zinc, this system effectively targets pruritus, epidermal hyperplasia, immune dysregulation, and infection, offering a promising ...
Xiaolong Xu, Chunhao Long, Yuze Zhou, Lujing Fei, Youyou Zhou, Min Qi   +5 more
wiley   +1 more source

Genomic perspectives on the global dissemination of Elizabethkingia anophelis: unveiling inherent multidrug resistance and virulence determinants. [PDF]

BMC Microbiol
Hu S, Meng X, Xu H, Ni S, Xiao Y, Zheng B.   +5 more
europepmc   +1 more source

Large‐Scale Structural Dynamics in the Tail Fiber Modulate the Infective Transition of the T7 Bacteriophage

Small, EarlyView.
During host recognition, the fibers of T7 bacteriophages transition from a capsid bound state to an extended conformation, which requires some level of fiber flexibility. By using high‐speed atomic force microscopy, we show that the fibers have an internal molecular hinge and a torsionally compliant coiled‐coil region.
Luca Elizabet Kosik, Miklós Cervenak, Dominik Sziklai, Andrea Balogh‐Molnár, Negar Rahimi, Bence Fehér, Soma Yamamoto, Hiroki Konno, Noriyuki Kodera, Holger Flechsig, Romain Amyot, Heinz Amenitsch, Hedvig Tordai, Levente Herényi, Ana Cuervo, Miklós Kellermayer, Bálint Kiss   +16 more
wiley   +1 more source

Hidden Infections, Emerging Resistance: Underdiagnosed Plasmodium vivax and Multidrug Resistance-1 (pvmdr1) Gene Amplification in the Guiana Shield. [PDF]

J Infect Dis
Puça MCSB, Mascarenhas MEP, Huguet QB, Salazar YEAR, Nogueira IR, Louzada J, de Pina-Costa A, de Siqueira AM, de Oliveira E Silva M, Pereira DB, Ladeia-Andrade S, Ferreira MU, Oliveira-Ferreira J, Gil JP, de Sousa TN.   +14 more
europepmc   +1 more source

Unraveling the Physicochemical Landscape of Organoselenium Compounds in Nanocarrier Systems

The Chemical Record, EarlyView.
Main nanocarriers employed to enhance the bioavailability and transport of organoselenium compounds. The image illustrates the key interaction forces that stabilize these organoselenium species in solution, enabling their application in drug delivery systems, catalysis, photoelectronic devices, and sensing technologies. In recent years, publications on
Romelly Eugenia Rojas Ramírez, Tielle Moraes de Almeida, Daiani Canabarro Leite, Gilson Zeni   +3 more
wiley   +1 more source

Association of biofilm formation with multidrug resistance in burn wound patients isolates of <i>Pseudomonas aeruginosa</i> in Sana'a City, Yemen. [PDF]

Front Med (Lausanne)
Maher AA, Maad AH, Al-Jaufy AY, Al-Shami HZ, Al-Saban AM, Al-Haifi AY, Al-Worafi YM, Al-Barq AM, Al-Yosffi EA, Naji Saad HM, Al-Dhabali AA, Thawaba ZA, Al-Shami AS.   +12 more
europepmc   +1 more source