Results 251 to 260 of about 349,410 (289)
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Multidrug-Resistance Transporters
2002P-glycoprotein was initially isolated due to its role in multidrug resistance to cancer chemotherapeutics. Recent work, however, makes it increasingly apparent that this transporter is also involved in the pharmacokinetics of many drugs. P-gp is strategically expressed in the luminal epithelial cells of organs often associated with drug absorption and ...
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Cancer chemotherapy and biological response modifiers, 1990
The understanding of the mechanism(s) of multidrug resistance has increased at a rapid rate over the past year. Many new inhibitors, new agents equitoxic to MDR and sensitive cells, techniques for screening, and application to therapies will no doubt be within the grasp of the clinical oncologist over the next few years.
R L, Fine, B A, Chabner
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The understanding of the mechanism(s) of multidrug resistance has increased at a rapid rate over the past year. Many new inhibitors, new agents equitoxic to MDR and sensitive cells, techniques for screening, and application to therapies will no doubt be within the grasp of the clinical oncologist over the next few years.
R L, Fine, B A, Chabner
openaire +3 more sources
Cancer surveys, 1987
Multidrug resistance describes a complex phenotype whose predominant feature is resistance to a wide range of structurally unrelated cytotoxic compounds, many of which are anticancer agents. This phenotype occurs frequently in mammalian cell lines and transplantable tumours selected for resistance to a single drug.
J H, Gerlach +3 more
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Multidrug resistance describes a complex phenotype whose predominant feature is resistance to a wide range of structurally unrelated cytotoxic compounds, many of which are anticancer agents. This phenotype occurs frequently in mammalian cell lines and transplantable tumours selected for resistance to a single drug.
J H, Gerlach +3 more
openaire +1 more source
Antibiotic resistance in the patient with cancer: Escalating challenges and paths forward
Ca-A Cancer Journal for Clinicians, 2021Amila K Nanayakkara, Kevin Outterson
exaly
Multidrug Resistant Tuberculosis
MCN, The American Journal of Maternal/Child Nursing, 1993openaire +2 more sources
Multidrug-resistance efflux pumps ? not just for resistance
Nature Reviews Microbiology, 2006Laura J V Piddock
exaly