Results 61 to 70 of about 365,495 (322)

Emerging crisis of multidrug-resistant enterococci from a rural tertiary care hospital of North India

Indian Journal of Health Sciences and Biomedical Research KLEU, 2021
INTRODUCTION: Enterococci are emerging as a major pathogen causing a variety of hospital-acquired nosocomial infections and community-acquired infections contributing significantly to patient's morbidity and mortality.
Jyoti Sangwan, Kirti Lohan, Pratibha Mane, Mukesh Kumar   +3 more
doaj   +1 more source

Bacterial Resistance Toward Antimicrobial Ionic Liquids Mediated by Multidrug Efflux Pumps [PDF]

, 2022
Tobias Gundolf, Roland Kalb, Peter Rossmanith, Patrick Mester   +3 more
openalex   +1 more source

Host‐Directed Biomaterials for Combatting Bloodstream Infections: From Macrocyclic Peptides to Immune‐Activating Cell Backpacks

Advanced Functional Materials, EarlyView.
Bloodstream infections (BSI) are one of the leading causes of mortality and morbidity in both civilian and military populations. This paper summarizes recent progress in novel treatment strategies to manage BSI arising from both bacterial and fungal pathogens using molecules, particles, and materials to elicit host‐directed immunity.
Thomas Thomou, Jagadish Krishnappa, Justin B. Schaal, Prasad Tongaonkar, Dat Q. Tran, Wenchao Gu, Yung‐Fu Chang, Michael E. Selsted, Shaoyi Jiang, Samir Mitragotri, Michael Super, Christopher J. Bettinger   +11 more
wiley   +1 more source

Multidrug Resistance: An Emerging Crisis

Interdisciplinary Perspectives on Infectious Diseases, 2014
The resistance among various microbial species (infectious agents) to different antimicrobial drugs has emerged as a cause of public health threat all over the world at a terrifying rate. Due to the pacing advent of new resistance mechanisms and decrease
Jyoti Tanwar, Shrayanee Das, Zeeshan Fatima, Saif Hameed   +3 more
doaj   +1 more source

Identification and characterisation of a novel multidrug-resistant streptococcus, Streptococcus toyakuensis sp. nov., from a blood sample

Journal of Global Antimicrobial Resistance, 2022
: Objectives: In 2018, we isolated multidrug-resistant α-haemolytic streptococci TP1632 from the blood of a 34-year-old patient with bacteraemia. This study aimed to characterise α-haemolytic streptococci TP1632 and elucidate its multidrug resistance ...
Takeaki Wajima, Atsuya Hagimoto, Emi Tanaka, Yoshiaki Kawamura, Hidemasa Nakaminami   +4 more
doaj   +1 more source

Development of Multidrug Resistance in Acute Myeloid Leukemia Is Associated with Alterations of the LPHN1/GAL-9/TIM-3 Signaling Pathway [PDF]

, 2021
Zuzana Kocibalova, Martina Guzyova, Ivana Borovská, Lucia Messingerová, Lucia Copáková, Zdena Sulová, Albert Breier   +6 more
openalex   +1 more source

New and Improved Diagnostics for Detection of Drug-Resistant Pulmonary Tuberculosis. [PDF]

, 2011
PURPOSE OF REVIEW: Tuberculosis (TB) remains a global emergency and continues to kill 1.7 million people globally each year. Drug-resistant TB is now well established throughout the world and most TB patients are not being screened for drug resistance ...
Affolabi, Albert, Banerjee, Blakemore, Boehme, Brossier, Bwanga, Caws, Coronel, Drews, Ellner, Ellner, Farnia, Fears, Garza-González, Gupta, Helb, Hillemann, Kiet, Kim, Lemaire, Lin, Ling, Martin, Martin, Martin, Migliori, Migliori, Minion, Morcillo, Neonakis, Nicol, Pai, Palomino, Piersimoni, Sandgren, Sohn, Van Rie, Visalakshi, Visalakshi, Wallis, Wright   +41 more
core   +1 more source

Liquid Crystalline Inverted Lipid Phases and Reverse Micelles in Drug Delivery: From Molecular Design to Therapeutic Potential

Advanced Functional Materials, EarlyView.
Liquid crystalline inverted lipid phases and reverse micelles are self‐assembled lipid nanostructures that enhance the solubility, stability, and delivery of diverse therapeutics. This review integrates their physicochemical principles, formulation strategies, drug loading mechanisms, and biomedical applications, highlighting their growing ...
Numan Eczacioglu, Mulazim Hussain Asim, Soheil Haddadzadegan, Andreas Bernkop‐Schnürch   +3 more
wiley   +1 more source

Relocation of active site carboxylates in major facilitator superfamily multidrug transporter LmrP reveals plasticity in proton interactions [PDF]

, 2016
The expression of polyspecific membrane transporters is one important mechanism by which cells can obtain resistance to structurally different antibiotics and cytotoxic agents.

core   +2 more sources

All‐Aqueous Pullulan Fibers Enabling Visible‐to‐Near‐Infrared Waveguiding with Mechanical and Thermal Resilience

Advanced Functional Materials, EarlyView.
Pullulan, a biomass‐derived polysaccharide, is transformed into transparent optical fibers using a solvent‐free borax hydrogel‐spinning method. The fibers outperform PMMA with ≈200 MPa tensile strength and 200 °C stability, while uniquely guiding visible‐to‐NIR light and enabling additive‐free humidity sensing.
Yuya Fukata, Aayush Kumar Jaiswal, Ari Hokkanen, Hannes Orelma, Tadahisa Iwata   +4 more
wiley   +1 more source