Results 11 to 20 of about 2,438,474 (193)
Detection approaches for multidrug resistance genes of leukemia [PDF]
Drug Design, Development and Therapy, 2017 Ying Du, Baoan Chen Department of Hematology and Oncology (Key Department of Jiangsu Medicine), School of Medicine, Zhongda Hospital, Southeast University, Nanjing, Jiangsu Province, People’s Republic of China Abstract: Leukemia is a clonal ...
Du Y, Chen B
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Prevention of multidrug resistance (MDR) in osteosarcoma by NSC23925 [PDF]
British Journal of Cancer, 2014 The major limitation to the success of chemotherapy in osteosarcoma is the development of multidrug resistance (MDR). Preventing the emergence of MDR during chemotherapy treatment has been a high priority of clinical and investigational oncology, but it remains an elusive goal.
Yang, X +10 more
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Predictors of Multidrug-Resistant Tuberculosis (MDR-TB) in Sudan [PDF]
Antibiotics, 2019 Multidrug-resistant tuberculosis (MDR-TB) is a global public health threat and burden on the health system. This is especially the case in high tuberculosis (TB) prevalence countries, such as Sudan. Consequently, this study aimed to ascertain the predictors of MDR-TB in Sudan to provide future guidance.
Monadil H. Ali +4 more
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International Journal of Mycobacteriology, 2017 Background: The first line anti-tuberculosis drug pyrazinamide (PZA) is important when treating PZA susceptible multidrug-resistant tuberculosis (MDR-TB). Several drug resistance surveys have however reported PZA resistance among a significant proportion
Mikael Mansjo +2 more
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Programmatically selected multidrug-resistant strains drive the emergence of extensively drug-resistant tuberculosis in South Africa [PDF]
, 2013 South Africa shows one of the highest global burdens of multidrug-resistant (MDR) and extensively drug-resistant (XDR) tuberculosis (TB). Since 2002, MDR-TB in South Africa has been treated by a standardized combination therapy, which until 2010 included
Pillay, Manormoney +69 more
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Function and Inhibitory Mechanisms of Multidrug Efflux Pumps
Frontiers in Microbiology, 2021 Multidrug efflux pumps are inner membrane transporters that export multiple antibiotics from the inside to the outside of bacterial cells, contributing to bacterial multidrug resistance (MDR). Postgenomic analysis has demonstrated that numerous multidrug
Kunihiko Nishino +4 more
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[Multidrug resistance (MDR) in oncology].
Anales de medicina interna (Madrid, Spain : 1984), 1997 Multidrug resistance or mdr is a frequent phenomenon for which tumor cells can develop, in only one step, cross-resistance to a different anticancer drugs such as antibiotics, vinca alkaloids and podophylotoxins. This is due to an extrusion of drugs out of the cells, since it is interrelated with the decrease of the intracellular concentration of the ...
A, Souvirón Rodríguez +3 more
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mSphere, 2017 Multidrug-resistant (MDR) Gram-negative organisms are a burden on the global health care system. The Tigecycline Evaluation and Surveillance Trial (TEST) is an ongoing global study designed to monitor the in vitro activities of tigecycline and a panel of
Anna Giammanco +3 more
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New Microbes and New Infections, 2018 Multidrug-resistant tuberculosis (MDR-TB) has emerged as a major public health problem. Drug-resistance surveillance data show that 3.9% of new and 21% of previously treated TB cases were estimated to have had rifampicin/ multidrug-resistant tuberculosis
O. Zewdie +6 more
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Molecules, 2020 Multidrug resistance (MDR) in cancer is one of the main limitations for chemotherapy success. Numerous mechanisms are behind the MDR phenomenon wherein the overexpression of the ATP-binding cassette (ABC) transporter proteins P-glycoprotein (P-gp ...
Bruno M. F. Gonçalves +2 more
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