Results 21 to 30 of about 2,438,474 (193)

Multidrug Resistance in Cancer: Understanding Molecular Mechanisms, Immunoprevention and Therapeutic Approaches

Frontiers in Oncology, 2022
Cancer is one of the leading causes of death worldwide. Several treatments are available for cancer treatment, but many treatment methods are ineffective against multidrug-resistant cancer.
Talha Bin Emran, Talha Bin Emran, Asif Shahriar, Aar Rafi Mahmud, Tanjilur Rahman, Mehedy Hasan Abir, Mohd. Faijanur - Rob Siddiquee, Hossain Ahmed, Nova Rahman, Firzan Nainu, Elly Wahyudin, Saikat Mitra, Kuldeep Dhama, Mahmoud M. Habiballah, Mahmoud M. Habiballah, Shafiul Haque, Shafiul Haque, Ariful Islam, Mohammad Mahmudul Hassan, Mohammad Mahmudul Hassan   +19 more
doaj   +1 more source

Multidrug-resistant tuberculosis (MDR-TB) and multidrug-resistant HIV (MDR-HIV) syndemic: challenges in resource limited setting [PDF]

BMJ Case Reports, 2019
Tuberculosis (TB) is common among persons living with HIV. This public health concern is aggravated by infection with multidrug-resistant organisms and adverse effects of polypharmacy. There are few published cases of multidrug-resistant tuberculosis (MDR-TB) in multidrug-resistant HIV (MDR-HIV) infected patients.
Christian, Francisco, Mary Ann, Lansang, Edsel Maurice, Salvana, Katerina, Leyritana   +3 more
openaire   +2 more sources

Pseudomonas aeruginosa Isolates from Clinical Specimens: Biofilm-Forming Ability and Association with Antibiotic Resistance [PDF]

Delta Journal of Science, 2023
Pseudomonas aeruginosa is a versatile pathogen known for its ability to cause infections and survive in various environments. Biofilm formation plays a critical role in its virulence. This study investigated different P.
Mohammed Eid, Fatma Abd El Aziz, Yehia Mahmoud   +2 more
doaj   +1 more source

Investigation of the role of LRP in multidrug resistance [PDF]

, 1998
There have been many reports linking the overexpression of the lung resistance-related protein (LRP) with cross-resistance to chemotherapeutic drugs.
Byrne, Daragh
core   +2 more sources

Native CRISPR-Cas-Mediated Genome Editing Enables Dissecting and Sensitizing Clinical Multidrug-Resistant P. aeruginosa

Cell Reports, 2019
Summary: Despite being fundamentally important and having direct therapeutic implications, the functional genomics of the clinical isolates of multidrug-resistant (MDR) pathogens is often impeded by the lack of genome-editing tools.
Zeling Xu, Ming Li, Yanran Li, Huiluo Cao, Lu Miao, Zhaochao Xu, Yusuke Higuchi, Seiji Yamasaki, Kunihiko Nishino, Patrick C.Y. Woo, Hua Xiang, Aixin Yan   +11 more
doaj   +1 more source

Metformin Derivative HL156A Reverses Multidrug Resistance by Inhibiting HOXC6/ERK1/2 Signaling in Multidrug-Resistant Human Cancer Cells

Pharmaceuticals, 2020
Multidrug resistance is a significant clinical crisis in cancer treatment and has been linked to the cellular expression of multidrug efflux transporters.
Yun Soo Jeong, Thuy Giang Lam, Seho Jeong, Sang-Gun Ahn   +3 more
doaj   +1 more source

THE COMPARATIVE ANALYSIS OF THE DRUG RESISTANCE OF MBTIN CHILDREN, ADOLESCENTS AND THE SOURCES OF INFECTION IN THE MULTIDRUG-RESISTANT TUBERCULOSIS FOCIES

Buletinul Academiei de Ştiinţe a Moldovei: Ştiinţe Medicale, 2021
145 patients (67 children and 78 adolescents) from the multidrug-resistant tuberculosis infection focies took partin the complex microbiological study.
Olha SAKHELASHVILI-BIL, Manana SAKHELASHVILI   +1 more
doaj   +1 more source

The prevalences of Salmonella Genomic Island 1 variants in human and animal Salmonella Typhimurium DT104 are distinguishable using a Bayesian approach [PDF]

, 2011
Throughout the 1990s, there was an epidemic of multidrug resistant Salmonella Typhimurium DT104 in both animals and humans in Scotland. The use of antimicrobials in agriculture is often cited as a major source of antimicrobial resistance in pathogenic ...
Matthew J Denwood, Reid, S W J, Derek J Brown, Daniel T Haydon, Mellor Dominic J., Mellor, D J, Louise Matthews, Alison E. Mather, Matthews, L., Reid Stuart W. J., Mather, A E, Haydon, D T, Derek J. Brown, Alison E Mather, John E Coia, Coia John E., Matthews, L, Mather, A.E., Stuart W J Reid, Daniel T. Haydon, Brown, D J, Denwood Matthew J., Haydon, D.T., Coia, J E, Dominic J. Mellor, Brown Derek J., John E. Coia, Coia, J.E., Reid, S.W.J., Matthew J. Denwood, Matthews Louise, Stuart W. J. Reid, Denwood, M.J., Denwood, M J, Mather Alison E., Mellor, D.J., Dominic J Mellor, Haydon Daniel T., Brown, D.J.   +38 more
core   +1 more source

AGE, GENDER, EDUCATIONAL LEVEL, OCCUPATIONAL, AND KNOWLEDGE LEVEL ABOUT MULTIDRUG RESISTANT TUBERCULOSIS (MDR-TB) AMONG TUBERCULOSIS PATIENTS

Nurse and Holistic Care, 2023
Background: Resistance of Mycobacterium Tuberculosis is a condition in which Anti-Tuberculosis (OAT) drugs are unable to kill the Mycobacterium Tuberculosis germs. One type of resistance is Multidrug Resistant Tuberculosis.
Fahrur Rozi, Fakhrun Nisa’ Fiddaroini, Prawito Prawito   +2 more
doaj   +1 more source

The nuclear membrane in multidrug resistance: microinjection of epirubicin into bladder cancer cell lines

, 2005
Objevtive: to assess whether microinjecting epirubicin into cells showing multidrug resistance (MDR, common to many cancers, including bladder cancer, with resistance to, e.g.
Birch, B.R, Hayes, C.M, Featherstone, J.F, Cooper, A.J, Speers, A.G, Lwaleed, B.A   +5 more
core   +1 more source