Results 31 to 40 of about 12,825 (196)

Composition and conservation of the mRNA-degrading machinery in bacteria

open access: yesJournal of Biomedical Science, 2011
RNA synthesis and decay counteract each other and therefore inversely regulate gene expression in pro- and eukaryotic cells by controlling the steady-state level of individual transcripts.
Kaberdin Vladimir R   +2 more
doaj   +1 more source

Engineering of Metabolic Pathways by Artificial Enzyme Channels. [PDF]

open access: yes, 2015
Application of industrial enzymes for production of valuable chemical compounds has greatly benefited from recent developments in Systems and Synthetic Biology.
Boccaccini, AR   +3 more
core   +3 more sources

Characterization of the mycobacterial acyl-CoA carboxylase holo complexes reveals their functional expansion into amino acid catabolism.

open access: yesPLoS Pathogens, 2015
Biotin-mediated carboxylation of short-chain fatty acid coenzyme A esters is a key step in lipid biosynthesis that is carried out by multienzyme complexes to extend fatty acids by one methylene group.
Matthias T Ehebauer   +12 more
doaj   +1 more source

Secretion and assembly of functional mini-cellulosomes from synthetic chromosomal operons in Clostridium acetobutylicum ATCC 824. [PDF]

open access: yes, 2013
Background: Consolidated bioprocessing (CBP) is reliant on the simultaneous enzyme production, saccharification of biomass, and fermentation of released sugars into valuable products such as butanol. Clostridial species that produce butanol are, however,
Bolam, DN   +7 more
core   +1 more source

Mitochondrial Enzymes of the Urea Cycle Cluster at the Inner Mitochondrial Membrane

open access: yesFrontiers in Physiology, 2021
Mitochondrial enzymes involved in energy transformation are organized into multiprotein complexes that channel the reaction intermediates for efficient ATP production.
Nantaporn Haskins   +19 more
doaj   +1 more source

Transiently Transfected Purine Biosynthetic Enzymes Form Stress Bodies [PDF]

open access: yes, 2013
It has been hypothesized that components of enzymatic pathways might organize into intracellular assemblies to improve their catalytic efficiency or lead to coordinate regulation.
Cook, Lindsey   +5 more
core   +6 more sources

Properties of Lactic Acid Microorganisms: Long-Term Preservation Methods [PDF]

open access: yesТехника и технология пищевых производств, 2018
Among the relevant studies on lactic acid bacteria there are projects devoted to the multienzyme complexes of starter cultures, new competitive bacterial concentrates and their use in fermented functional milk products.
Kriger O., Noskova S.
doaj   +1 more source

Cellular localization of the hybrid pyruvate/2-oxoglutarate dehydrogenase complex in the actinobacterium Corynebacterium glutamicum

open access: yesMicrobiology Spectrum, 2023
For many bacterial proteins, specific localizations within the cell have been demonstrated, but enzymes involved in central metabolism are usually considered to be homogenously distributed within the cytoplasm. Here, we provide an example for a spatially
Lea Sundermeyer   +5 more
doaj   +1 more source

The dynamic organization of fungal acetyl-CoA carboxylase [PDF]

open access: yes, 2016
Acetyl-CoA carboxylases (ACCs) catalyse the committed step in fatty-acid biosynthesis: the ATP-dependent carboxylation of acetyl-CoA to malonyl-CoA. They are important regulatory hubs for metabolic control and relevant drug targets for the treatment of ...
Hagmann, Anna   +4 more
core   +1 more source

Protein kinase A (PKA) phosphorylation of Shp2 inhibits its phosphatase activity and modulates ligand specificity. [PDF]

open access: yes, 2015
Pathological cardiac hypertrophy (an increase in cardiac mass resulting from stress-induced cardiac myocyte growth) is a major factor underlying heart failure.
Burmeister, BT   +5 more
core   +1 more source

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