ALLELE FREQUENCIES IN MULTIGENE FAMILIES [PDF]
Journal of the Indonesian Mathematical Society, 2012 Results on allelle frequencies in three chromosomes, drawn at randomfrom a diploid population, evolving in equilibrium, at a particular generation, arepresented in this paper. The genes on each chromosome are subject to unbiased andreciprocal gene conversion and mutation.
openaire +2 more sources
Targeted disruption of py235ebp-1: Invasion of erythrocytes by Plasmodium yoelii using an alternative Py235 erythrocyte binding protein [PDF]
, 2011 Plasmodium yoelii YM asexual blood stage parasites express multiple members of the py235 gene family, part of the super-family of genes including those coding for Plasmodium vivax reticulocyte binding proteins and Plasmodium falciparum RH proteins.
Cunningham, Deirdre A. +9 more
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Genome Sequencing Uncovers Additional Findings in Phelan‐McDermid Syndrome
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.ABSTRACT Phelan‐McDermid syndrome (PMS) is a genetic condition caused by deletions of chromosome 22q13.3 or pathogenic variants in the SHANK3 gene. Neurologic features typically include intellectual disability, autism spectrum disorder, hypotonia, and absent speech, though there is considerable variability even among individuals with the same molecular
Rachel Gore Moses +21 more
wiley +1 more source
A Novel SPAST/SPG4 Splice-Site Variant in a Family with Dominant Hereditary Spastic Paraplegia
Case Reports in Neurological Medicine, 2020 Some causes of spastic paraplegia are treatable and many are not. Diagnostic work-up to determine the etiology can be costly and invasive. Here we report the case of a man with slowly progressive spastic paraparesis.
Nathaniel M. Robbins +4 more
doaj +1 more source
Biological applications of the theory of birth-and-death processes [PDF]
, 2005 In this review, we discuss the applications of the theory of birth-and-death processes to problems in biology, primarily, those of evolutionary genomics. The mathematical principles of the theory of these processes are briefly described.
Karev, Georgy P. +2 more
core
Study on differential expression of 1-aminocyclopropane-1-carboxylic acid oxidase genes in table grape cv. Thompson Seedless [PDF]
, 2013 As a consequence of the non-climacteric status of grapes (Vitis vinifera), ethylene biosynthesis and signal transduction have scarcely been studied in this fruit.
Campos-Vargas, Reinaldo +5 more
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Animal Research and One Health, EarlyView.The paper is divided into three main sections: a review of the development of spatial transcriptomics technology, its applications in livestock and poultry research, and its future prospects. This article provides an overview of the current state of spatial transcriptomics in animal research, exploring its integration with multiomics technologies as ...
Mingyu Wang +5 more
wiley +1 more source
A multigene family encoding surface glycoproteins in Trypanosoma congolense
Microbial Cell, 2017 Trypanosoma congolense, the causative agent of the most important livestock disease in Africa, expresses specific surface proteins involved in its parasitic lifestyle. Unfortunately, the complete repertoire of such molecules is far from being deciphered.
Magali Thonnus +2 more
doaj +1 more source
Multi-gene panel testing for hereditary cancer predisposition in unsolved high-risk breast and ovarian cancer patients. [PDF]
, 2017 PurposeMany women with an elevated risk of hereditary breast and ovarian cancer have previously tested negative for pathogenic mutations in BRCA1 and BRCA2. Among them, a subset has hereditary susceptibility to cancer and requires further testing.
Adams, Sophie B +8 more
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Molecular evolution of the toll-like receptor multigene family in birds.
Molecular biology and evolution, 2011 Toll-like receptors (TLR) are membrane-bound sensors of the innate immune system that recognize invariant and distinctive molecular features of invading microbes and are also essential for initiating adaptive immunity in vertebrates.
M. Alcaide, S. Edwards
semanticscholar +1 more source