Results 91 to 100 of about 70,091 (229)

Contribution of MUTYH variants to male breast cancer risk: results from a multicenter study in Italy [PDF]

, 2018
Inherited mutations in BRCA1, and, mainly, BRCA2 genes are associated with increased risk of male breast cancer (MBC). Mutations in PALB2 and CHEK2 genes may also increase MBC risk.
Azzollini, Jacopo, Bianchi, Simonetta, Bonanni, Bernardo, Bucalo, Agostino, Calistri, Daniele, Catucci, Irene, Coppa, Anna, Cortesi, Laura, Manoukian, Siranoush, Masala, Giovanna, Montagna, Marco, Ottini, Laura, Palli, Domenico, Peterlongo, Paolo, Radice, Paolo, Rizzolo, Piera, Russo, Antonio, Silvestri, Valentina, Spinelli, Alessandro Mauro, Tibiletti, Maria Grazia, Tommasi, Stefania, Valentini, Virginia, Varesco, Liliana, Viel, Alessandra, Zanna, Ines, Zelli, Veronica   +25 more
core   +3 more sources

Incidental Colorectal Adenomas in Adolescents: Clinical Management, Genetic Evaluation, and Surveillance

Journal of Gastroenterology and Hepatology, EarlyView.
Adolescents with incidental colorectal adenomas require age‐conscious management balancing referral for genetic counseling with evidence‐based surveillance. This narrative review proposes a pragmatic clinical algorithm integrating adenoma characteristics, hereditary risk assessment, and guideline‐concordant follow‐up to support individualized ...
Brett J. Hoskins, Shlomi Cohen, Colleen B. Flahive, Isabel Rojas, Aparajita Singh, Thomas M. Attard   +5 more
wiley   +1 more source

CpERF‐WRI1 Manipulates Ethylene Sensing by Regulating the Expression of CpERS1 and Fruit Ripening in Papaya

Plant Biotechnology Journal, EarlyView.
ABSTRACT Ethylene plays a crucial role in fruit ripening and is perceived by specialised receptor proteins embedded in the endoplasmic reticulum (ER) membrane. As an ethylene antagonist, 1‐methylcyclopropene (1‐MCP) binds to these receptors and delays papaya ripening, but improper use can cause ripening disorders.
Ziling Wu, Jiahui Cai, Faiz Ur Rahman, Wang Zheng, Qiunan Zhu, Weixin Chen, Xueping Li, Xiaoyang Zhu   +7 more
wiley   +1 more source

Regulation of ethylene biosynthesis in Festuca novae-zelandiae (Hack.) Cockayne and in Festuca aruninaceae (Schreb.) in response to a water deficit : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Plant Biology at Massey University, Palmerston North, New Zealand [PDF]

, 2006
Changes in ethylene evolution and the associated biosynthetic enzyme ACC oxidase to a water deficit, were examined in intact leaves of Fostuca novae-zelandiae and F. arundinacea cultivar 'Roa' (syn. Schedonorus phoenix).
Sheridan, Rachael Elizabeth
core  

Vaccination with parasite-specific TcTASV proteins combined with recombinant baculovirus as a delivery platform protects against acute and chronic Trypanosoma cruzi infection

Frontiers in Cellular and Infection Microbiology
Chagas’ is a neglected disease caused by the eukaryotic kinetoplastid parasite, Trypanosoma cruzi. Currently, approximately 8 million people are infected worldwide, most of whom are in the chronic phase of the disease, which involves cardiac, digestive ...
Yamil E. Masip, Yamil E. Masip, Lucas D. Caeiro, Lucas D. Caeiro, Maximiliano Cosenza, Maximiliano Cosenza, Miriam Postan, Guido Molina, Oscar Taboga, María Paula Molinari, Valeria Tekiel, Valeria Tekiel   +11 more
doaj   +1 more source

Gallic Acid‐Responsive microRNAs Reprogram Lignification During Drought Acclimation Process in Spearmint

Plant Biotechnology Journal, EarlyView.
ABSTRACT Mentha spicata L. (spearmint) is a high‐value aromatic and medicinal species, whose productivity is strongly affected by water deficit. Nevertheless, the molecular mechanisms underlying drought acclimation in this mint remain largely unexplored. Thus, here, we investigated the microRNA‐mediated regulatory processes triggered in M.
Alessia D'Agostino, Gabriele Di Marco, Gerardo Pepe, Adelaide Teofani, Chiara Pontecorvi, Manuela Helmer‐Citterich, Antonella Canini, Angelo Gismondi   +7 more
wiley   +1 more source

Beyond Starch: Towards a Scalable Potato Platform for Molecular Farming

Plant Biotechnology Journal, EarlyView.
Re‐engineering potato as a biosafe and host‐optimised platform for plant molecular farming by integrating intrinsic biological traits with targeted engineering strategies. ABSTRACT Thirty‐five years after the first recombinant protein was produced in potato and 30 years after clinical trials of edible vaccines from its tubers, the crop is being ...
Izabela Anna Chincinska, Dorota Sołtys‐Kalina, Audrey Y.‐H. Teh   +2 more
wiley   +1 more source

Cell-free prediction of protein expression costs for growing cells [PDF]

, 2017
Translating heterologous proteins places significant burden on host cells, consuming expression resources leading to slower cell growth and productivity.
Borkowski, O, Bricio, C, Ellis, T, Murgiano, M, Rothschild-Mancinelli, B, Stan, G   +5 more
core   +5 more sources

Methionine Synthase Positively Regulates Plant Defence to Both RNA and DNA Viruses and Is Useful for Developing Broad‐Spectrum Antiviral Resistance in Crops

Plant Biotechnology Journal, EarlyView.
ABSTRACT Plant viruses frequently cause severe economic losses in worldwide crop production. Developing broad‐spectrum resistance is the most efficient approach for controlling plant viral diseases. In this work, we found that the 17K protein of barley yellow dwarf viruses (BYDVs), which has multiple functions in viral pathogenesis including acting as ...
Zhaohui Wang, Kunpu Zhang, Chi Zhang, Jin Yang, Bei Li, Lina Wang, Zhenghao Shi, Rui Guo, Shuai Zhang, Kaiqi Gao, Jianing Li, Xiaohuan Jin, Xiang Ji, Huihui Bi, Liyuan You, Huaibing Jin, Daowen Wang   +16 more
wiley   +1 more source

Evolutionary analysis of CD300A and CD300C paired receptors in primates

Frontiers in Immunology
IntrodctionThe CD300 family comprises immunoglobulin superfamily receptors that regulate immune cell function through inhibitory or activating signals. CD300A and CD300C form a paired receptor system that recognizes shared ligands but mediates opposing ...
Carolina Dias, Carolina Dias, Francesca Levi-Schaffer, Pedro José Esteves, Pedro José Esteves, Pedro José Esteves   +5 more
doaj   +1 more source