Results 71 to 80 of about 42,962 (201)

Evolutionary analysis of CD300A and CD300C paired receptors in primates

Frontiers in Immunology
IntrodctionThe CD300 family comprises immunoglobulin superfamily receptors that regulate immune cell function through inhibitory or activating signals. CD300A and CD300C form a paired receptor system that recognizes shared ligands but mediates opposing ...
Carolina Dias, Carolina Dias, Francesca Levi-Schaffer, Pedro José Esteves, Pedro José Esteves, Pedro José Esteves   +5 more
doaj   +1 more source

Homology models for the PERB11 multigene family

Folding and Design, 1998
PERB11 is a multicopy polymorphic gene family found in association with HLA Class I genes within the major histocompatibility complex (MHC). Although its function is unknown, PERB11 has sequence similarities to HLA Class I and other related proteins. To explore the possible functional roles for PERB11, homology models have been constructed using both ...
Chelvanayagam, Gareth, Monaco, Antony, Lalonde, John Philippe, Tay, Guan K, Dawkins, RL   +4 more
openaire   +2 more sources

The Coalescent and Infinite-Site Model of a Small Multigene Family

, 2003
The infinite-site model of a small multigene family with two duplicated genes is studied. The expectations of the amounts of nucleotide variation within and between two genes and linkage disequilibrium are obtained, and a coalescent-based method for ...
印南, 秀樹, INNAN, Hideki
core  

Genetic characterization of Plectorhinchus mediterraneus yields important clues about genome organization and evolution of multigene families

BMC Genetics, 2012
Background Molecular and cytogenetic markers are of great use for to fish characterization, identification, phylogenetics and evolution. Multigene families have proven to be good markers for a better understanding of the variability, organization and ...
Merlo Manuel A, Pacchiarini Tiziana, Portela-Bens Silvia, Cross Ismael, Manchado Manuel, Rebordinos Laureana   +5 more
doaj   +1 more source

Sequence of a complete chicken BG haplotype shows dynamic expansion and contraction of two gene lineages with particular expression patterns.

PLoS Genetics, 2014
Many genes important in immunity are found as multigene families. The butyrophilin genes are members of the B7 family, playing diverse roles in co-regulation and perhaps in antigen presentation.
Jan Salomonsen, John A Chattaway, Andrew C Y Chan, Aimée Parker, Samuel Huguet, Denise A Marston, Sally L Rogers, Zhiguang Wu, Adrian L Smith, Karen Staines, Colin Butter, Patricia Riegert, Olli Vainio, Line Nielsen, Bernd Kaspers, Darren K Griffin, Fengtang Yang, Rima Zoorob, Francois Guillemot, Charles Auffray, Stephan Beck, Karsten Skjødt, Jim Kaufman   +22 more
doaj   +1 more source

Co-ordinate regulation of cytokinin gene family members during flag leaf and reproductive development in wheat

BMC Plant Biology, 2012
Background As the global population continues to expand, increasing yield in bread wheat is of critical importance as 20% of the world’s food supply is sourced from this cereal.
Song Jiancheng, Jiang Lijun, Jameson Paula   +2 more
doaj   +1 more source

The stevor multigene family of Plasmodium falciparum . [PDF]

, 2007
The stevor family is the third largest multigene family in the P. falciparum 3D7 genome (Gardner et al., 2002). With 30 copies estimated per genome, each encoding a predicted transmembrane spanning protein: a conserved N-terminal domain is followed by ...
Blythe, J.E.
core  

Characterization of a New Multigene Family Encoding Isomaltases in the Yeast Saccharomyces cerevisiae , the IMA Family

, 2010
International audienceIt has been known for a long time that the yeast Saccharo-myces cerevisiae can assimilate-methylglucopyranoside and isomaltose. We here report the identification of 5 genes (YGR287c, YIL172c, YJL216c, YJL221c and YOL157c), which ...
Teste, Marie-Ange, Jean Marie François, Parrou, Jean-Luc, Marie-Ange Teste, François, Jean Marie, Jean-Luc Parrou   +5 more
core   +1 more source

Clinical application of multigene panels: challenges of next generation counseling and cancer risk management

Frontiers in Oncology, 2015
Background: Multigene panels can be a cost- and time-effective alternative to sequentially testing multiple genes, especially with a mixed family cancer phenotype.
Thomas Paul Slavin, Mariana eNiell-Swiller, Ilana eSolomon, Bita eNehoray, Christina eRybak, Kathleen eBlazer, Jeffrey N Weitzel   +6 more
doaj   +1 more source

Genetic variation in small multigene families

Genetical Research, 1981
SUMMARYIn order to understand the evolution of genetic systems in which two genes are tandemly repeated (small multigene family) such as has been recently found in the haemoglobin α loci of primates, haemoglobin β loci of mouse and rarbit and other proteins, a population genetics approach was used.
openaire   +2 more sources