Results 81 to 90 of about 3,478,892 (251)

Homology models for the PERB11 multigene family

Folding and Design, 1998
PERB11 is a multicopy polymorphic gene family found in association with HLA Class I genes within the major histocompatibility complex (MHC). Although its function is unknown, PERB11 has sequence similarities to HLA Class I and other related proteins. To explore the possible functional roles for PERB11, homology models have been constructed using both ...
Chelvanayagam, Gareth, Monaco, Antony, Lalonde, John Philippe, Tay, Guan K, Dawkins, RL   +4 more
openaire   +2 more sources

Transgenic selection and underlying mechanisms in apicomplexan parasites

The FEBS Journal, EarlyView.
Transgenic selection markers have driven genetic engineering in apicomplexans, enabling precise, iterative experiments. This review discusses mechanistic details of drug selection markers, strategies for marker recycling, and practical considerations for several clinically relevant parasites.
Swaroop Peddiraju, Rakhee Lohia, Nishith Gupta   +2 more
wiley   +1 more source

Advanced Molecular Analysis in Hemophilia A in a Single Step: Next Generation Sequencing (NGS) and Copy Number Variation (CNV) Analysis

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Background Hemophilia A, an X‐linked bleeding disorder caused by pathogenic variants in the F8 gene, requires precise genetic diagnosis for optimal management. Conventional stepwise sequence and copy number variation (CNV) analyses are time‐consuming and may leave some cases unresolved.
Enise Avci Durmusalioglu, Esra Isik, Basak Durmus Ozen, Mehmet Mert Topaloglu, Nihal Karadas, Kaan Kavakli, Melike Sezgin Evim, Tolga Aslan, Erşen Kavak, Adalet Meral Gunes, Funda Tayfun Kupesiz, Alphan Kupesiz, Fahri Sahin, Tahir Atik   +13 more
wiley   +1 more source

Family medicine : present and future

, 2013
Contents: Future prospects of the College - Pierre Mallia; The contemporary College and Council - Jason J Bonnici; Immersion pulmonary oedema in a scuba diver - Mario Saliba; eHealth and mHealth - bridging gaps in health care - Martina FalzonThe ...
Mallia, Pierre, Malta College of Family Doctors, Agius, Dominic   +2 more
core  

Teaching Chronic Pain in the Family Medicine Clerkship: Influences of Experience and Beliefs About Treatment Effectiveness: A CERA Study [PDF]

, 2016
BACKGROUND: Chronic pain is a common and important disease state in North America, but many medical students and practicing physicians feel poorly prepared to treat this condition._x000D_ METHODS: Data were collected via the 2014 CERA Family Medicine ...
Zoberi, Kimberly Schiel, Antoun, Jumana M., Everard, Kelly M.   +2 more
core  

Enhancing Parents' Experiences of Paediatric Genomic Testing in Usual Outpatient Care: Insights From a Multi‐Perspective Qualitative Study

Journal of Paediatrics and Child Health, EarlyView.
ABSTRACT Aim The aim of this research was to explore what makes (or would make) for good genomic care delivered wholly or in part by paediatricians. Methods An interpretive description, qualitative study with parents of children offered genomic testing as an outpatient for a condition other than cancer; general and subspecialist paediatricians; nurses;
Erin Crellin, Melissa Martyn, Selima Ymer, Maya Pinn, Emma Weisz, Clara Gaff, Belinda Dawson‐McClaren   +6 more
wiley   +1 more source

Crawling under the radar: Two novel Paulinella species expand knowledge about the ecology and evolution of a primary plastid‐containing amoeba lineage

Journal of Phycology, EarlyView.
Abstract The genus Paulinella represents a rare, independent case of primary endosymbiosis, providing a unique system to study the early stages of organelle evolution. Here, we expand current understanding of primary plastid endosymbiosis through the discovery and characterization of two novel photosynthetic amoebae, Paulinella marae sp. nov.
Julia Van Etten, Sungpil Han, John A. Burns, Duckhyun Lhee, Andrew C. Willoughby, Timothy G. Stephens, Erin Chille, Robin S. Sleith, Debashish Bhattacharya, Hwan Su Yoon   +9 more
wiley   +1 more source

Co-ordinate regulation of cytokinin gene family members during flag leaf and reproductive development in wheat

BMC Plant Biology, 2012
Background As the global population continues to expand, increasing yield in bread wheat is of critical importance as 20% of the world’s food supply is sourced from this cereal.
Song Jiancheng, Jiang Lijun, Jameson Paula   +2 more
doaj   +1 more source

Genome‐scale insights into metabolic streamlining and photosynthetic energy balance in the extremophile green alga Picocystis salinarum (Picocystophyceae, Chlorophyta)

Journal of Phycology, EarlyView.
Abstract Picocystis salinarum is an early‐diverging chlorophyte and the sole described member of the Picocystophyceae, frequently dominating hypersaline and alkaline lakes despite extreme physicochemical constraints. To elucidate the genomic foundations of its ecological success, we generated a fully annotated, chromosome‐scale nuclear genome assembly ...
Claude Lemieux, Christian Otis, Monique Turmel   +2 more
wiley   +1 more source

Batchelor family collection

, 1898
This collection consists of a diary, pages from the family scrapbook, and genealogical materials related to the Batchelor family of Little Rock ...
Batchelor family
core   +1 more source