Results 81 to 90 of about 3,761,028 (302)
Molecular diagnostic testing identified mCRPC patients with BRCA mutations eligible for targeted therapies. Testing success is often contingent on the quality of tissue handling and laboratory processing techniques to minimize DNA degradation and suboptimal sequencing data quality.
Arun A. Azad+4 more
wiley +1 more source
Plant defense multigene families: I. Divergence of Fusarium solani-induced expression in Pisum and Lathyrus [PDF]
The defense response in plants challenged with pathogens is characterized by the activation of a diverse set of genes. Many of the same genes are induced in the defense responses of a wide range of plant species. How plant defense gene families evolve may therefore provide an important clue to our understanding of how disease resistance evolves ...
arxiv
A New Multigene Family of Putative Pheromone Receptors [PDF]
The vomeronasal organ (VNO) mediates detection of pheromones related to social and reproductive behavior in most terrestrial vertebrates. We have identified a new multigene family of G protein-linked receptors (V2Rs) that are specifically expressed in the VNO.
N. J. Ryba, TIRINDELLI, Roberto
openaire +3 more sources
Our study suggests that exome sequencing adds approximately 60% of the diagnostic yield in fetuses with skeletal abnormalities reported in previous literature. The dysplasia phenotypes had a higher incremental yield, whereas the dysostoses group according to this study had a relatively lower yield, especially in the isolated dysostoses group.
Yan Wang+6 more
wiley +1 more source
Ancestral Graph with Bias in Gene Conversion [PDF]
Gene conversion is a mechanism by which a double-strand break in a DNA molecule is repaired using a homologous DNA molecule as a template. As a result, one gene is 'copied and pasted' onto the other gene. It was recently reported that the direction of gene conversion appears to be biased towards G and C nucleotides.
arxiv
Asteroid Family Associations of Active Asteroids [PDF]
We report on the results of a systematic search for associated asteroid families for all active asteroids known to date. We find that 10 out of 12 main-belt comets (MBCs) and 5 out of 7 disrupted asteroids are linked with known or candidate families, rates that have ~0.1% and ~6% probabilities, respectively, of occurring by chance, given an overall ...
arxiv +1 more source
Protection of the Rights of Large Families as One of the Key Tasks of the State's Social Policy [PDF]
The authors of the article analyze the policy of the Russian government in the field of family support, paying attention to legal programs at the federal and regional levels. The maternity capital program is considered separately, as well as measures aimed at supporting large families.
arxiv
A multigene phylogeny was constructed, including a significant number of representative species of the main lineages in the Xylariaceae and four DNA loci the internal transcribed spacer region (ITS), the large subunit (LSU) of the nuclear rDNA, the ...
Lucile Wendt+10 more
semanticscholar +1 more source
During the pathological process of immune thrombocytopenia, signal transducer and activator of transcription 3 (STAT3) is activated by JAKs, leading to the production of a large number of inflammatory cytokines and promoting the activation of Th1, Th2 and Th17 cells.
Yingbin Yue+4 more
wiley +1 more source
Plant class III peroxidases (PRXs) catalyze generation of reactive oxygen species and oxidation of various compounds including lignin precursors. PRXs function in cell wall metabolism, defense, and stress responses. However, gene redundancy and catalytic
Vincent P. M. Aparato+5 more
doaj +1 more source