Results 111 to 120 of about 3,327,081 (222)

Scaling temporal resolution from mice to humans: Challenges and innovations in preclinical imaging of translational models

The Journal of Physiology, EarlyView.
Abstract figure legend Temporal scaling physiology differs significantly between mice and humans. Mice have higher metabolism, heart and respiratory rate, as well as faster blood flow rates, brain activity and physiological dynamics over time. These differences influence the temporal resolution needed in preclinical imaging of mouse models to ...
Sara Gargiulo, Matteo Gramanzini
wiley   +1 more source

De‐Escalation of Neoadjuvant Treatment for HER2‐Positive Breast Cancer

International Journal of Cancer, Volume 159, Issue 10, Page 2393-2402, 15 November 2026.
ABSTRACT With improved prognosis in early HER2‐positive breast cancer, safely de‐escalating treatment is increasingly investigated to minimize overtreatment. This article focuses on neoadjuvant de‐escalation strategies for HER2‐positive breast cancer.
Yiyin Ma, Dedian Chen, Sheng Huang
wiley   +1 more source

Predicting cytogenetic risk in multiple myeloma using conventional whole-body MRI, spinal dynamic contrast-enhanced MRI, and spinal diffusion-weighted imaging

Insights into Imaging
Objectives Cytogenetic abnormalities are predictors of poor prognosis in multiple myeloma (MM). This paper aims to build and validate a multiparametric conventional and functional whole-body MRI-based prediction model for cytogenetic risk classification ...
Thomas Van Den Berghe, Bert Verberckmoes, Nicolas Kint, Steven Wallaert, Nicolas De Vos, Chloé Algoet, Maxim Behaeghe, Julie Dutoit, Nadine Van Roy, Philip Vlummens, Amélie Dendooven, Jo Van Dorpe, Fritz Offner, Koenraad Verstraete   +13 more
doaj   +1 more source

Survival After Hematopoietic Stem Cell Transplantation in Diamond–Blackfan Anemia Syndrome: The Role of Iron Overload—A Systematic Review

Pediatric Blood &Cancer, Volume 73, Issue 11, November 2026.
ABSTRACT We assessed the effect of iron overload (IO) on mortality and complications following hematopoietic stem cell transplantation (HSCT) in patients with Diamond–Blackfan anemia syndrome (DBAS) in a systematic review of individual participant data and cohort data from observational studies.
Geoffrey Z. L. Kuppens, Evangelia Kiakou, Lieke de Zwart, Maurizio Miano, Eduard J. van Beers, Marc Bierings, Marije Bartels   +6 more
wiley   +1 more source

Diagnosis of Caroli Disease with Gadoxetic Acid-Enhanced Magnetic Resonance Imaging

Caroli disease (CD) is a condition in which there are multiple cystic dilations of the bile ducts within the liver that are present from birth. In this case report, we present the imaging findings of a 33-year-old woman who was diagnosed noninvasively ...
Ramazan Orkun Önder, Serdar Aslan, Tumay Bekci   +2 more
core   +1 more source

Multiparametric Mapping via Cardiovascular Magnetic Resonance in the Risk Stratification of Ventricular Arrhythmias and Sudden Cardiac Death

Medicina
Risk stratification for malignant ventricular arrhythmias and sudden cardiac death is a daunting task for physicians in daily practice. Multiparametric mapping sequences obtained via cardiovascular magnetic resonance imaging can improve the risk ...
Maria Lo Monaco, Kamil Stankowski, Stefano Figliozzi, Flavia Nicoli, Vincenzo Scialò, Alessandro Gad, Costanza Lisi, Federico Marchini, Carlo Maria Dellino, Rocco Mollace, Federica Catapano, Giulio Giuseppe Stefanini, Lorenzo Monti, Gianluigi Condorelli, Erika Bertella, Marco Francone   +15 more
doaj   +1 more source

Combined ADC and T2 Mapping in the Prostate Using a 3D Reduced FOV Sequence

Magnetic Resonance in Medicine, Volume 96, Issue 5, Page 2292-2308, November 2026.
ABSTRACT Purpose To develop a 3D reduced FOV sequence for combined ADC and T2 mapping in the prostate in a single scan. Methods A 3D ADC and T2 mapping reduced FOV acquisition is enabled using T2 and diffusion preparation modules with slab‐selective tip‐down pulses and magnitude stabilizer gradients.
Yannik Ott, Sarah McElroy, Raphael Tomi‐Tricot, Carolyn Horst, Patricia A. Gutierrez, Rahul Khamar, Omar Darwish, Vicky Goh, Radhouene Neji   +8 more
wiley   +1 more source

Phase‐Sensitive Modeling Improves Fat DESPOT Multiparametric Relaxation Mapping in Fat‐Water Mixtures

Magnetic Resonance in Medicine, Volume 96, Issue 5, Page 2336-2349, November 2026.
ABSTRACT Purpose To improve on a multiparametric technique—known as Fat DESPOT—to map the fat‐ and water‐specific R1 (R1f, R1w), R2*, and proton density fat fraction (PDFF) by upgrading the parameter initialization and introducing explicit model sensitivity to the complex phase of the water and fat signals.
Renée‐Claude Bider, Cristian Ciobanu, Jorge Campos Pazmiño, Véronique Fortier, Evan McNabb, Ives R. Levesque   +5 more
wiley   +1 more source

Dosimetric evaluation of systematic source position uncertainty along the source path and robust planning during MRI‐only cervical HDR brachytherapy

Journal of Applied Clinical Medical Physics, Volume 27, Issue 10, October 2026.
Abstract Background The knowledge of the dosimetric impact of systematic source position uncertainty and the use of a methodology for robust treatment planning against such uncertainty can help improve the quality of treatment plans, during MR‐only cervical brachytherapy treatment.
Amritpal Singh, Raffi Karshafian, Ananth Ravi, Moti Raj Paudel   +3 more
wiley   +1 more source

Brown Adipose Tissue: Molecular Mechanisms of Regulation, Physiological Functions, and Therapeutic Targets

MedComm, Volume 7, Issue 10, October 2026.
This review systematically covers three core dimensions of brown adipose tissue (BAT): multilayered regulatory mechanisms governing brown adipocyte differentiation and phenotypic identity, physiological functions and signaling pathways in mediating thermogenesis and systemic metabolic crosstalk between BAT and multiple organs, and emerging clinical in ...
Xiaoli Deng, Yuanyuan Shen, Ying Sun, Lu Lu, Chongkui Sun   +4 more
wiley   +1 more source