Results 151 to 160 of about 21,339 (261)

3D‐Printable, Honeycomb‐Inspired Tissue‐Like Bioelectrodes for Patient‐Specific Neural Interface

open access: yesAdvanced Materials, Volume 38, Issue 31, 2 June 2026.
3D printed MRI‐compatible tissue‐like neural electrodes tailored to individual gyral patterns. This honeycomb‐inspired printable gel electrode (HiPGE) employs a bioinspired architecture with soft hydrogels, engineered to match the softness of brain tissue.
Marzia Momin   +12 more
wiley   +1 more source

Tailoring Vascular‐Immune Homeostasis via Manganese‐DNA Complex‐Armed Immunogenic Extracellular Vesicles for Pancreatic Cancer Immunotherapy

open access: yesAdvanced Science, Volume 13, Issue 35, 24 June 2026.
This study demonstrates that Mn2⁺–tumor DNA complexes encapsulated in dendritic cell (DC)– derived immunogenic extracellular vesicles (EVDC@Mn‐DNA) act as a DC‐specific cGAS– STING activator. EVDC@Mn‐DNA treatment enhances intratumoral DC activation, improves tumor vascular function, promotes CD8⁺ T cell activity, and suppresses pancreatic tumor growth,
Xue Jiang   +13 more
wiley   +1 more source

The development of a high speed 3D 2-photon microscope for neuroscience

open access: yes, 2010
The progress of neuroscience is limited by the instrumentation available to it for studying the brain. At present, there is a serious instrumentation gap between functional Magnetic Resonance Imaging (fMRI) of whole brains and the microscopic scale ...
Kirkby, P.A.
core  

Mechanoadaptation via Myosin Cytoplasmic Redistribution Protects Circulating Tumor Cells From Shear‐induced Death During Hematogenous Dissemination

open access: yesAdvanced Science, Volume 13, Issue 33, 15 June 2026.
This study investigates how CTCs survive varying shear stress during hematogenous metastasis. We uncover a self‐protection mechanism, by which non‐adherent CTCs adapt to high shearing milieu through accumulated cytoplasmic myosin‐mediated disruption of myosin‐actin binding, attenuating force transmission into chromatin to protect CTCs from shear ...
Cunyu Zhang   +10 more
wiley   +1 more source

Adaptive optics sharpens multiphoton-microscope images

open access: yes, 2005
Originally developed for astronomy and military use, adaptive-optics is coming into its own for use in ­optical-sectioning microscopy techniques such as multiphoton ...
Booth, M., Girkin, J.M.
core  

A large field-of-view, single-cell-resolution two- and three-photon microscope for deep and wide imaging

open access: yeseLight
In vivo imaging of large-scale neuronal activity plays a pivotal role in unraveling the function of the brain's circuitry. Multiphoton microscopy, a powerful tool for deep-tissue imaging, has received sustained interest in advancing its speed, field of ...
Aaron T. Mok   +9 more
doaj   +1 more source

Value of multiphoton microscopy in uro-oncology: a narrative review. [PDF]

open access: yesTransl Androl Urol, 2023
Treacy PJ   +7 more
europepmc   +1 more source

Quantum Dots for Biomedical Biosensing, NIR‐II Bioimaging, and Phototherapy: Materials Design, Signal Transduction, and Translational Barriers

open access: yesAdvanced Science, Volume 13, Issue 33, 15 June 2026.
This review outlines bottom‐up and biomimetic fabrication strategies of quantum dots, and highlights their emerging applications in biosensing, multimodal bioimaging, and intelligent cancer theranostics. It further discusses key translational barriers and future perspectives for advancing QD‐based nanomedicine toward clinical implementation.
Jie Ju   +5 more
wiley   +1 more source

Evaluation of a gain-managed nonlinear fiber amplifier for multiphoton microscopy. [PDF]

open access: yesBiomed Opt Express, 2023
Sidorenko P   +5 more
europepmc   +1 more source

Stimuli‐Responsive Hydrogels for Optical Applications: Mechanisms, Architectures, and Translational Challenges

open access: yesAggregate, Volume 7, Issue 6, June 2026.
The review discusses stimuli‐responsive hydrogels as soft optical materials that translate physical, chemical, and biological cues into refractive‐index, scattering, birefringence, diffraction, and transparency changes. It examines major stimulus classes and photonic architectures for biosensing, waveguiding, adaptive lenses, smart windows, and therapy.
Andrés Bernal‐Ballén   +2 more
wiley   +1 more source

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