Results 161 to 170 of about 21,339 (261)

Effects of Objective Numerical Apertures on Achievable Imaging Depths in Multiphoton Microscopy

, 2009
Multiphoton microscopy is a powerful technique for achieving three- dimensional submicron imaging in biological specimens . However, specimen optical parameters such as refractive indices and scattering coefficients can result in the loss of image ...
董致寬;孫嬿;駱文;林頌然;紀秀華;董成淵, TUNG, CHIH-KUAN;SUN, YEN;LO, WEN;LIN, SUNG-JAN;JEE, SHIOU-HWA;DONG, CHEN-YUAN   +1 more
core  

Endogenously generated Dutch‐type Aβ non‐fibrillar aggregates dysregulate presynaptic neurotransmission in the absence of detectable inflammation

Alzheimer's &Dementia, Volume 22, Issue 6, June 2026.
Abstract BACKGROUND APPE693Q (“Dutch”) transgenic mice develop aging‐related learning deficits and accumulate endogenously generated non‐fibrillar aggregates (NFAs) of amyloid beta (Aβ) and amyloid precursor protein α‐carboxy terminal fragments. NFA‐Aβ correlates with synaptic loss and memory deficits more closely than does fibrillar Aβ.
Emilie L. Castranio, Merina Varghese, Elentina K. Argyrousi, Kuldeep Tripathi, Yong Huang, Akiko Asada, Linda Söderberg, Erin Bresnahan, David Lerner, Francesca Garretti, Hong Zhang, Jonathan van de Loo, Cheryl D. Stimpson, Ronan Talty, Charles Glabe, Efrat Levy, Minghui Wang, Marjan Ilkov, Toshiharu Suzuki, Kanae Ando, Bin Zhang, Lars Lannfelt, Brigitte Guérin, William D. Lubell, Shai Rahimipour, Dara L. Dickstein, Sam Gandy, Ottavio Arancio, Michelle E. Ehrlich   +28 more
wiley   +1 more source

High Speed Miniaturized Multiphoton Microscopy with Elliptical Beam Excitation. [PDF]

Biomed Opt, 2023
Mattison B, Liu SJ, Tian F, Yang W.
europepmc   +1 more source

New Insights Into the Role of Neutrophils in Lymphoma

Cancer Medicine, Volume 15, Issue 6, June 2026.
Tissue‐resident neutrophils challenge conventional paradigms by actively infiltrating normal lymphoid organs, predominantly localizing in interstitial compartments, a spatial distribution distinct from their classical vascular positioning. Neutrophils in lymphoid organs exhibit unique phenotypic and functional signatures, suggesting they play roles in ...
Ling Gu
wiley   +1 more source

The Effect of Diabetes Mellitus Type 1 on the Energy Metabolism of Hepatocytes: Multiphoton Microscopy and Fluorescence Lifetime Imaging. [PDF]

Int J Mol Sci, 2023
Rodimova S, Bobrov N, Mozherov A, Elagin V, Karabut M, Ermakova P, Shchechkin I, Kozlov D, Krylov D, Gavrina A, Kashina A, Zagainov V, Zagaynova E, Kuznetsova D.   +13 more
europepmc   +1 more source

Nonlinear Imaging Allows to Characterize Granulomas and Fibrosis in Mice Tissue From Experimental Schistosomiasis

Journal of Biophotonics, Volume 19, Issue 6, June 2026.
Second Harmonic Generation and Two‐Photon Excitation Fluorescence microscopy allows to characterize mice tissues infected with Schistosoma mansoni in an experimental model. ABSTRACT Schistosomiasis is a neglected disease caused by parasites of the genus Schistosoma that poses serious public health problems.
Gladystone Rocha da Fonseca, Rennan R. M. Lima, Ronald Eduardo Soares, Bárbara Regina Melo Ribeiro, Paulo E. Cabral Filho, Adriana Fontes, Ana Maria de Paula   +6 more
wiley   +1 more source

Controversies Surrounding Critical‐Size Defects: Influence of Age and Biological Characteristics

Journal of Biomedical Materials Research Part B: Applied Biomaterials, Volume 114, Issue 6, June 2026.
ABSTRACT Critical‐size defects (CSDs) in craniofacial reconstruction refer to osseous gaps that fail to heal spontaneously, increasing the risk of neurological impairment and craniofacial dysmorphology. Despite decades of investigation, controversy still exists surrounding the definition of CSDs, with criteria varying across species, experimental ...
Andrew Nordlund, Hana Shah, Nicholas A. Mirsky, Kashyap K. Tadisina, Arturo J. Rios‐Diaz, Vasudev Vivekanand Nayak, Estevam A. Bonfante, Paulo G. Coelho   +7 more
wiley   +1 more source

In vivo detection of healthy skin: Comparison of multiphoton microscopy and reflectance confocal microscopy. [PDF]

Skin Res Technol, 2023
Chen KJ, Wang ZY, Han Y, Cui Y.
europepmc   +1 more source

Collagen III Deficiency Following Injury in Female Murine Tendons Alters Matrix Composition, Structure, Organization and Function

Journal of Orthopaedic Research, Volume 44, Issue 6, June 2026.
ABSTRACT Tendons withstand large forces due to an aligned, dense collagen matrix. However, their low cellularity and relative inability to recruit reparative cells post‐injury, coupled with a susceptibility to excessive scarring results in loss of tendon structure and function. Type III collagen (COL3) plays a key role in regulating matrix architecture
J. A. Carlson, W. Yen, S. N. Weiss, S. W. Volk, L. J. Soslowsky   +4 more
wiley   +1 more source

Label-free multiphoton microscopy and machine learning for recognition of hepatocellular carcinoma. [PDF]

Sci Rep
Galli R, Korn S, Aust D, Baretton GB, Weitz J, Koch E, Riediger C.   +6 more
europepmc   +1 more source