Results 41 to 50 of about 21,339 (261)

In vivo multiphoton microscopy of melasma [PDF]

open access: yesPigment Cell & Melanoma Research, 2018
AbstractMelasma is a skin disorder characterized by hyperpigmented patches due to increased melanin production and deposition. In this pilot study, we evaluate the potential of multiphoton microscopy (MPM) to characterize non‐invasively the melanin content, location, and distribution in melasma and assess the elastosis severity.
Griffin Lentsch   +10 more
openaire   +4 more sources

A phasor approach analysis of multiphoton FLIM measurements of three-dimensional cell culture models

open access: yes, 2022
Paper 97120XFluorescence lifetime imaging microscopy (FLIM) is a useful approach to obtain information regarding the endogenous fluorophores present in biological samples.
Schenke-Layland, Katja   +5 more
core   +1 more source

Intravital Two-photon Imaging of Dynamic Alteration of Hepatic Lipid Droplets in Fasted and Refed State

open access: yesJournal of Lipid and Atherosclerosis, 2021
Objective The liver plays a central role in lipid metabolism. During fasting and feeding, the fatty acid trafficking between adipose tissue and liver induces accumulation and dissociation of dynamic hepatic lipid droplets (LDs).
Jieun Moon, Pilhan Kim
doaj   +1 more source

Label-free 3D visualization of cellular and tissue structures in intact muscle with second and third harmonic generation microscopy. [PDF]

open access: yes, 2011
Second and Third Harmonic Generation (SHG and THG) microscopy is based on optical effects which are induced by specific inherent physical properties of a specimen.
Krombach Fritz   +11 more
core   +1 more source

A Novel Assay Allowing Drug Self-Administration, Extinction, and Reinstatement Testing in Head-Restrained Mice

open access: yesFrontiers in Behavioral Neuroscience, 2021
Multiphoton microscopy is one of several new technologies providing unprecedented insight into the activity dynamics and function of neural circuits. Unfortunately, some of these technologies require experimentation in head-restrained animals, limiting ...
Kelsey M. Vollmer   +12 more
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Tangle-bearing neurons survive despite disruption of membrane integrity in a mouse model of tauopathy [PDF]

open access: yes, 2009
Neurofibrillary tangles (NFTs) are associated with neuronal loss and correlate with cognitive impairment in Alzheimer disease, but how NFTs relate to neuronal death is not clear.
Carlson, George A   +4 more
core   +1 more source

Label-free detection of breast masses using multiphoton microscopy. [PDF]

open access: yesPLoS ONE, 2013
Histopathology forms the gold standard for the diagnosis of breast cancer. Multiphoton microscopy (MPM) has been proposed to be a potentially powerful adjunct to current histopathological techniques.
Xiufeng Wu   +8 more
doaj   +1 more source

Image reconstruction of multiphoton microscopy data [PDF]

open access: yes2009 IEEE International Symposium on Biomedical Imaging: From Nano to Macro, 2009
The techniques introduced in this paper allow for accurate multi-scale image reconstruction of multi-photon microscopy data. Multi-photon microscopy (MPM) is a tool for the non-invasive imaging of living organisms and tissue. The data acquired using this technique can contain information about the position, excited state lifetime, and spectra of the ...
Jared Doot   +3 more
openaire   +2 more sources

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Home - About - Disclaimer - Privacy