Reliable detection of Burkholderia pseudomallei using multiple cross displacement amplification label-based biosensor [PDF]
Background Burkholderia pseudomallei (B. pseudomallei), as a highly pathogenic organism, causes melioidosis, which is a disease of public health importance in many tropical developing countries.
Xiaoxia Wang +4 more
doaj +6 more sources
Real-time multiple cross displacement amplification assay for rapid and sensitive detection of Haemophilus influenzae [PDF]
Haemophilus influenzae is an opportunistic pathogen usually causing bacteremia, meningitis, and pneumonia in children. Here, we developed a method based on multiple cross displacement amplification (MCDA) method and real-tme fluorescence technique for ...
Chunrong Sun +10 more
doaj +5 more sources
Real-time fluorescent multiple cross displacement amplification for rapid and sensitive Mycoplasma pneumoniae detection [PDF]
Mycoplasma pneumoniae is a significant pathogen responsible for community-acquired pneumonia, predominantly affecting children and adolescents. Here, we devised a rapid method for M.
Fei Xiao +11 more
doaj +5 more sources
Highly sensitive and rapid determination of Mycobacterium leprae based on real-time multiple cross displacement amplification [PDF]
Background Mycobacterium leprae (ML) is the pathogen that causes leprosy, which has a long history and still exists today. ML is an intracellular mycobacterium that dominantly induces leprosy by causing permanent damage to the skin, nerves, limbs and ...
Junfei Huang +7 more
doaj +5 more sources
Visual and fluorescent detection of Moraxella catarrhalis by multiple cross displacement amplification-based assay [PDF]
Moraxella catarrhalis (M. catarrhalis), once considered as a harmless commensal bacterium, is now recognized as a significant pathogen associated with human mucosal infection.
Xiaolan Huang +11 more
doaj +5 more sources
Multiple Cross Displacement Amplification Coupled with Lateral Flow Biosensor (MCDA-LFB) for rapid detection of Legionella pneumophila [PDF]
Background Legionella pneumophila is an opportunistic waterborne pathogen of significant public health problems, which can cause serious human respiratory diseases (Legionnaires’ disease).
Luxi Jiang +5 more
doaj +6 more sources
Multiple cross displacement amplification combined with nanoparticle-based lateral flow biosensor for rapid and sensitive detection of Epstein-Barr virus [PDF]
IntroductionEpstein-Barr virus (EBV) is a highly dangerous virus that is globally prevalent and closely linked to the development of nasopharyngeal cancer (NPC).
Xinbei Jia +11 more
doaj +5 more sources
Ultrasensitive and highly specific detection of the Brucella genus and B. melitensis by CRISPR/Cas12b‐multiple cross displacement amplification technique [PDF]
Brucellosis is caused by members of the Brucella spp. and remains one of the world’s major zoonotic diseases. Brucella melitensis (B. melitensis) as the most contagious Brucella species cannot be ignored as an essential source of infection for ...
Sha Mao +7 more
doaj +5 more sources
Multiple cross displacement amplification (MCDA) for rapid detection of toxigenic Clostridioides difficile as a potential point-of-care testing [PDF]
Toxigenic Clostridioides difficile is the cause of C. difficile infection, highlighting the critical need for rapid and easy-to-use detection. In this study, a multiple cross displacement amplification (MCDA) assay was developed to detect toxigenic C ...
Hui Hu +11 more
doaj +5 more sources
Rapid and sensitive detection of human adenovirus types 3 and 7 using CRISPR-Cas12b coupled with multiple cross displacement amplification [PDF]
Background: Human adenovirus type 3 (HAdV-3) and 7 (HAdV-7) are significant causative agents of acute respiratory tract infections that are prevalent among school-based outbreaks across China. Rapid and accurate diagnosis is crucial for effective control
Xinbei Jia +6 more
doaj +3 more sources

