Results 11 to 20 of about 792,799 (305)
Туберкулез и болезни лёгких, 2022 The objective: to evaluate main parameters of cellular, humoral immunity and natural resistance in tuberculosis patients with primary and acquired multiple drug resistance; to study the correlation of these parameters with clinical and radiological ...
E. Lesnik, S. Ginda
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Revista Panamericana de Salud Pública, 2020 Acinetobacter baumannii is considered to be a worldwide threat to public health due to its high antimicrobial resistance rates and the severe infections it can cause. Little is known about this pathogen’s resistance in Central America.
Julio Cesar Zuniga-Moya +9 more
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Chromothripsis in Treatment Resistance in Multiple Myeloma [PDF]
Genomics & Informatics, 2017 Multiple myeloma (MM) is a malignant disease caused by an abnormal proliferation of plasma cells, of which the prognostic factors include chromosomal abnormality, β-2 microglobulin, and albumin. Recently, the term chromothripsis has emerged, which is the
Kyoung Joo Lee +7 more
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Microbiology Research, 2016 Due to the increasing prevalence of infections caused by resistant bacteria and especially multiple drug resistance Enterobacteriaceae, availability of alternative effective antibiotics is restricted.
Fatemeh Yeganeh Sefidan +2 more
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Insulin resistance in drug naive patients with multiple sclerosis [PDF]
Vojnosanitetski Pregled, 2017 Background/Aim. Due to the fact that there is a relatively small number of data related to systemic insulin abnormalities in the multiple sclerosis (MS), the main objective of our study was to determine whether a dysbalance of glucose and ...
Kostić Smiljana +5 more
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Targeting Drug Chemo-Resistance in Cancer Using Natural Products
Biomedicines, 2021 Cancer is one of the leading causes of death globally. The development of drug resistance is the main contributor to cancer-related mortality. Cancer cells exploit multiple mechanisms to reduce the therapeutic effects of anticancer drugs, thereby causing
Wamidh H. Talib +4 more
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Xiehe Yixue Zazhi, 2023 Objective To study the resistance of Helicobacter pylori(Hp) isolated from Peking University People's Hospital to commonly used antibiotics, in order to provide basis for clinical rational drug use.
ZHANG Feifei +7 more
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Epigenetic Regulation of Antifungal Drug Resistance
Journal of Fungi, 2022 In medical mycology, epigenetic mechanisms are emerging as key regulators of multiple aspects of fungal biology ranging from development, phenotypic and morphological plasticity to antifungal drug resistance.
Sandip Patra +3 more
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Selinexor Overcomes Hypoxia-Induced Drug Resistance in Multiple Myeloma
Translational Oncology, 2017 Increased levels of the nuclear export protein, exportin 1 (XPO1), were demonstrated in multiple myeloma (MM) patients. Targeting XPO1 with selinexor (the selective inhibitor of nuclear export; SINE compound KPT-330) demonstrates broad antitumor activity
Barbara Muz +4 more
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m6A Modification in Non-Coding RNA: The Role in Cancer Drug Resistance
Frontiers in Oncology, 2021 Cancer drug resistance has always been a major difficulty in cancer therapy. In the face of drug pressure, resistant cancer cells show complex molecular mechanisms including epigenetic changes to maintain survival. Studies prove that cancer cells exhibit
Chen Chen +9 more
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