Results 11 to 20 of about 809,845 (306)

Antimicrobial profile of Acinetobacter baumannii at a tertiary hospital in Honduras: a cross-sectional analysis

open access: yesRevista Panamericana de Salud Pública, 2020
Acinetobacter baumannii is considered to be a worldwide threat to public health due to its high antimicrobial resistance rates and the severe infections it can cause. Little is known about this pathogen’s resistance in Central America.
Julio Cesar Zuniga-Moya   +9 more
doaj   +1 more source

Chromothripsis in Treatment Resistance in Multiple Myeloma [PDF]

open access: yesGenomics & Informatics, 2017
Multiple myeloma (MM) is a malignant disease caused by an abnormal proliferation of plasma cells, of which the prognostic factors include chromosomal abnormality, β-2 microglobulin, and albumin. Recently, the term chromothripsis has emerged, which is the
Kyoung Joo Lee   +7 more
doaj   +1 more source

Fosfomycin, a therapeutic option for infections produced by multiple drug-resistant Enterobacteriaceae

open access: yesMicrobiology Research, 2016
Due to the increasing prevalence of infections caused by resistant bacteria and especially multiple drug resistance Enterobacteriaceae, availability of alternative effective antibiotics is restricted.
Fatemeh Yeganeh Sefidan   +2 more
doaj   +1 more source

Insulin resistance in drug naive patients with multiple sclerosis [PDF]

open access: yesVojnosanitetski Pregled, 2017
Background/Aim. Due to the fact that there is a relatively small number of data related to systemic insulin abnormalities in the multiple sclerosis (MS), the main objective of our study was to determine whether a dysbalance of glucose and ...
Kostić Smiljana   +5 more
doaj   +1 more source

Targeting Drug Chemo-Resistance in Cancer Using Natural Products

open access: yesBiomedicines, 2021
Cancer is one of the leading causes of death globally. The development of drug resistance is the main contributor to cancer-related mortality. Cancer cells exploit multiple mechanisms to reduce the therapeutic effects of anticancer drugs, thereby causing
Wamidh H. Talib   +4 more
doaj   +1 more source

Clinical Resistance of Helicobacter pylori and Its Trend: A 10-year Data Analysis at Peking University People's Hospital

open access: yesXiehe Yixue Zazhi, 2023
Objective  To study the resistance of Helicobacter pylori(Hp) isolated from Peking University People's Hospital to commonly used antibiotics, in order to provide basis for clinical rational drug use.
ZHANG Feifei   +7 more
doaj   +1 more source

Epigenetic Regulation of Antifungal Drug Resistance

open access: yesJournal of Fungi, 2022
In medical mycology, epigenetic mechanisms are emerging as key regulators of multiple aspects of fungal biology ranging from development, phenotypic and morphological plasticity to antifungal drug resistance.
Sandip Patra   +3 more
doaj   +1 more source

m6A Modification in Non-Coding RNA: The Role in Cancer Drug Resistance

open access: yesFrontiers in Oncology, 2021
Cancer drug resistance has always been a major difficulty in cancer therapy. In the face of drug pressure, resistant cancer cells show complex molecular mechanisms including epigenetic changes to maintain survival. Studies prove that cancer cells exhibit
Chen Chen   +9 more
doaj   +1 more source

Efficacy and safety of bedaquiline in treatment regimens in patients TB/HV co-infection in the Udmurt Republic

open access: yesТуберкулез и болезни лёгких, 2023
The objective: to evaluate the efficacy and safety of bedaquiline in new chemotherapy regimens in HIV-positive tuberculosis patients.Subjects and Methods.
O. E. Russkikh   +3 more
doaj   +1 more source

The role of non‐coding RNAs in drug resistance of oral squamous cell carcinoma and therapeutic potential

open access: yesCancer Communications, 2021
Oral squamous cell carcinoma (OSCC), the eighth most prevalent cancer in the world, arises from the interaction of multiple factors including tobacco, alcohol consumption, and betel quid.
Xiang Meng   +7 more
doaj   +1 more source

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