Results 41 to 50 of about 2,245,687 (336)
Oral squamous cell carcinoma (OSCC), the eighth most prevalent cancer in the world, arises from the interaction of multiple factors including tobacco, alcohol consumption, and betel quid.
Xiang Meng +7 more
doaj +1 more source
Multiscale modelling of cancer progression and treatment control : the role of intracellular heterogeneities in chemotherapy treatment [PDF]
Cancer is a complex, multiscale process involving interactions at intracellular, intercellular and tissue scales that are in turn susceptible to microenvironmental changes.
Chaplain, Mark Andrew Joseph +1 more
core +1 more source
Left-Sided Endocarditis Associated with Multi-Drug Resistance Acinetobacter Lwoffii [PDF]
Acinetobacter lwoffii, an important nosocomial pathogen, is a gram-negative aerobic bacillus that is a component of the normal flora on the skin, oropharynx, and perineum of about 20-25% of healthy individuals.
Hossein Ahmadi +4 more
doaj +1 more source
Objective: To assess the epidemic situation in the Russian Federation on tuberculosis with multidrug-resistant and extensively drug-resistant (MDR, XDR) of the pathogen and the effectiveness of its treatment.
A.E. ERGESHOV +5 more
doaj +1 more source
Increased expression of a microRNA correlates with anthelmintic resistance in parasitic nematodes [PDF]
Resistance to anthelmintic drugs is a major problem in the global fight against parasitic nematodes infecting humans and animals. While previous studies have identified mutations in drug target genes in resistant parasites, changes in the expression ...
Bartley, David +13 more
core +2 more sources
Intra-Vesical Colistin for Pseudomonas aeruginosa Urinary Tract Infections
The numbers of multiple drug-resistant Gram-negative bacterial infections are rising worldwide. The threat is increased by the lack of new antibiotics, so clinicians are turning to older drugs previously abandoned due to their recognized toxicity, such ...
Rui Encarnado Assis +6 more
doaj +1 more source
Promising Anti-Mitochondrial Agents for Overcoming Acquired Drug Resistance in Multiple Myeloma
Multiple myeloma (MM) remains an incurable tumor due to the high rate of relapse that still occurs. Acquired drug resistance represents the most challenging obstacle to the extension of survival and several studies have been conducted to understand the ...
Vanessa Innao +4 more
doaj +1 more source
Understanding and targeting resistance mechanisms in cancer
Resistance to cancer therapies has been a commonly observed phenomenon in clinical practice, which is one of the major causes of treatment failure and poor patient survival. The reduced responsiveness of cancer cells is a multifaceted phenomenon that can
Zi‐Ning Lei +6 more
doaj +1 more source
The emergence of resistance to the benzimidazole anthlemintics in parasitic nematodes of livestock is characterised by multiple independent hard and soft selective sweeps [PDF]
Anthelmintic resistance is a major problem for the control of parasitic nematodes of livestock and of growing concern for human parasite control. However, there is little understanding of how resistance arises and spreads or of the “genetic signature” of
Bartley, Yvonne +7 more
core +3 more sources
The multidrug-resistance (MDR) phenotype expressed in mammalian cell lines is complex. A cell selected with a single agent can acquire cross-resistance to a remarkably wide range of compounds which have no structural or functional similarities. The basis for cross-resistance seems to be a decreased net cellular accumulation of the drugs involved, and ...
C R, Leveille, A S, Moore
openaire +3 more sources

