Results 51 to 60 of about 2,245,687 (336)
Pediatric Blood &Cancer, EarlyView.ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson +3 more
wiley +1 more source
Туберкулез и болезни лёгких, 2022 The objective: to identify and systematize social and demographic risk factors for the development and spread of multiple drug resistant tuberculosis (MDR TB) in the Russian Federation (RF) by means of a systematic review of existing publications ...
I. A. Bykov
doaj +1 more source
Peroxiredoxin III : a candidate for drug resistance to chemotherapy : a thesis presented in partial fulfillment of the requirements for the degree of Master of Science in Biochemistry at Massey University, Palmerston North, New Zealand [PDF]
, 2008 The development of drug resistance to chemotherapeutic drugs is a serious obstacle in the successful treatment of cancer. New cancer drugs are continually being developed with the goal of increasing the effectiveness of chemotherapy.
Aalderink, Miranda
core
In vitro development of chemotherapy and targeted therapy drug-resistant cancer cell lines: a practical guide with case studies [PDF]
, 2014 The development of a drug-resistant cell line can take from 3 to 18 months. However, little is published on the methodology of this development process. This article will discuss key decisions to be made prior to starting resistant cell line development;
Breen, Laura +7 more
core +2 more sources
The Transfer of Sphingomyelinase Contributes to Drug Resistance in Multiple Myeloma
Cancers, 2019 Multiple myeloma (MM) is well-known for the development of drug resistance, leading to relapse. Therefore, finding novel treatment strategies remains necessary. By performing a lipidomics assay on MM patient plasma, we aimed to identify new targets.
S. Faict +13 more
semanticscholar +1 more source
Туберкулез и болезни лёгких, 2018 The article presents the evaluation of safety and efficiency of chemotherapy regimens including the new anti-tuberculosis agent of bedaquiline in 21 pulmonary tuberculosis patients with multiple and extensive drug resistance who were treated in Stavropol
N. M. Konovаlovа +3 more
doaj +1 more source
A genomic and evolutionary approach reveals non-genetic drug resistance in malaria [PDF]
, 2014 Background: Drug resistance remains a major public health challenge for malaria treatment and eradication. Individual loci associated with drug resistance to many antimalarials have been identified, but their epistasis with other resistance mechanisms ...
Broadbent, Kate M +11 more
core +1 more source
Multiple Mechanisms Synergistically Induce Pseudomonas Aeruginosa Multiple Drug Resistance [PDF]
, 2021 Abstract Background: This study was designed to detect the molecular epidemiological characteristics and resistant mechanism of carbapenem resistant Pseudomonas aeruginosa (CRPA) which provide reference for the prevention and treatment of hospital CRPA infection.
Lulu Yang +5 more
openaire +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background The management of clinically apparent single lesions or oligofocal nephroblastomatosis, a facultative precursor of nephroblastoma, remains debated. Methods We retrospectively analyzed 37 patients with clinically apparent single or oligofocal nephroblastomatosis (two to three lesions per kidney) among 2347 patients registered between
Nils Welter +17 more
wiley +1 more source
Туберкулез и болезни лёгких, 2017 In 2015 the implementation of Edicts no. 951 by the Russian Ministry of Health On Guidelines on Improvement of Respiratory Tuberculosis Treatment and Diagnostics was started.Goal of the study: to analyze the characteristics of tuberculosis patients ...
E. P. Myshkova +2 more
doaj +1 more source