Results 91 to 100 of about 23,289 (161)

Preoperative and postoperative pathology concordance in endometrial intraepithelial neoplasia: A retrospective cohort study

open access: yesInternational Journal of Gynecology &Obstetrics, Volume 175, Issue 1, Page 336-344, October 2026.
Abstract Objective To assess the concordance between pre‐ and postoperative pathology in patients with endometrial intraepithelial neoplasia (EIN) undergoing hysterectomy, and identify predictors of malignancy, including sampling method, progestin therapy, and surgical timing.
Jenny Dimakos   +6 more
wiley   +1 more source

Bilateral adrenal tumor related to multiple endocrine neoplasia type 2

open access: yesUrological Science, 2015
Meng-Che Chiang   +2 more
doaj   +1 more source

From prevalence to precision: Integrating phenotype, symptoms, reproductive goals, and treatment in leiomyoma care

open access: yesInternational Journal of Gynecology &Obstetrics, Volume 175, Issue 1, Page 11-17, October 2026.
Abstract Uterine fibroids (leiomyomas) are present in most women during their reproductive years, yet only a subset becomes clinically meaningful. This disparity poses a central clinical challenge: distinguishing symptoms caused by fibroids from those unrelated to them.
Malcolm G. Munro
wiley   +1 more source

Iron and Other Metal Ions in Human Health and Disease

open access: yesMedComm, Volume 7, Issue 10, October 2026.
Iron, copper, zinc, and calcium orchestrate cellular function through distinct yet cooperative mechanisms: redox‐active iron and copper cycle between oxidation states to act as Fenton catalysts and electron carriers in oxidative phosphorylation (OXPHOS); redox‐inert zinc serves as a structural component of zinc‐finger proteins and a catalytic cofactor ...
Xiaofeng Dai, Jitian Li
wiley   +1 more source

Cancer Cell Metastasis: From Molecular Mechanisms to Therapeutic Strategies

open access: yesMedComm, Volume 7, Issue 10, October 2026.
The schematic representation of intrinsic and extrinsic influences of cancer cell metastasis. Genomic evolution of metastatic tumor cells (MTCs) promotes their metastatic phenotypes and reconstruct the primary tumor microenvironment. During MTCs migration along different routes (blood circulation, lymphatic vessels, and perineuronal spaces), the ...
Yupeng Zhao   +7 more
wiley   +1 more source

Successful management of a multiple endocrine neoplasia type 1‐associated thymic neuroendocrine neoplasms with acute chest pain as initial symptom: A rare case report

open access: yesClinical Case Reports
Key Clinical Message Acute chest pain can be the first manifestation of multiple endocrine neoplasia type 1(MEN1)‐associated thymic neuroendocrine neoplasms (NEN). Comprehensive treatment may be an effective strategy for MEN1‐associated NEN.
Xuesong Li   +5 more
doaj   +1 more source

Colorectal Cancer: Epidemiology, Risk Factors, Signaling Pathways, Clinical Features, Screening, Diagnosis, and Management

open access: yesMedComm, Volume 7, Issue 10, October 2026.
Colorectal cancer is a heterogeneous, adaptive disease shaped by population‐level risk, genomic and epigenetic alterations, tumor ecosystem evolution, and treatment pressure. This review integrates epidemiology, risk factors, signaling networks, clinical presentation, screening, molecular diagnosis, and stage‐ and biomarker‐guided management while ...
Kairui Wan   +6 more
wiley   +1 more source

Testicular Biopsies in Adolescent and Adult Andrological Patients: The EAA Clinical Guidelines

open access: yesAndrology, Volume 14, Issue 7, Page 1906-1928, October 2026.
ABSTRACT Background Histological evaluation of testicular tissue is central to the assessment of infertile men, particularly those at an increased risk of testicular germ cell tumors (TGCT). Traditionally, testicular biopsies have been used primarily for diagnostic purposes, such as the detection of germ cell neoplasia in situ (GCNIS). With advances in
Lise Aksglaede   +11 more
wiley   +1 more source

Malignancy in Pediatric Hyperfunctioning Thyroid Nodules: A Case Report and Literature Review

open access: yesClinical Endocrinology, Volume 105, Issue 4, Page 474-485, October 2026.
ABSTRACT Background Thyroid nodules are rare in children but carry a markedly higher risk of malignancy compared to adults (20%–26% vs. 5%). Hyperfunctioning thyroid nodules are exceptionally uncommon in the pediatric population and are typically benign.
Cristina Clausi   +12 more
wiley   +1 more source

Insulin, Semaglutide and Dapagliflozin in Adults With Type 1 Diabetes: Design and Methods of Triple Therapy for Type 1 Diabetes (TTT1)—An International Phase 3 Clinical Trial

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 10, Page 8812-8824, October 2026.
ABSTRACT Aims Attaining target glycaemia can be a challenge in Type 1 Diabetes (T1D) due to insulin‐induced weight gain. Adjunct therapy with modern glucose‐lowering agents developed for type 2 diabetes (T2D) has great potential but may be insufficiently efficacious and carries risks of hypoglycaemia and ketosis.
Joseph G. Timmons   +11 more
wiley   +1 more source

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