Results 151 to 160 of about 354,322 (345)

I-OPen: inferior outcomes of penta-refractory compared to penta-exposed multiple myeloma patients

open access: yesBlood Cancer Journal, 2022
Sarvarinder K. Gill   +9 more
doaj   +1 more source

Mechanisms of spinal glial activation in chemotherapy‐induced peripheral neuropathy: Focus on microglia and astrocytes

open access: yesIbrain, EarlyView.
Chemotherapy‐induced peripheral neuropathy (CIPN) remains a major clinical challenge, with central sensitization considered an important pathological mechanism in its occurrence and persistence. This review focuses on spinal astrocytes and microglia, systematically summarizing the pathological mechanisms of spinal glial cells involved in CIPN caused by
Long Gu, Song Cao, Yonghuai Feng
wiley   +1 more source

Thrombosis is associated with inferior survival in multiple myeloma

open access: gold, 2012
Sigurður Y. Kristinsson   +4 more
openalex   +2 more sources

Development and psychometric properties of a general cancer stigma scale

open access: yesInternational Journal of Cancer, EarlyView.
What's New? Cancer‐related stigma can fuel anxiety and depression and lead to self‐isolation, delayed treatment, and decreased quality of life. The extent to which stigma impacts cancer patients, however, remains uncertain. This study applied mixed methods in high‐ and low‐income settings, with cohorts in the U.S. state of Utah and Lilongwe, Malawi, to
Stephen M. Kimani   +11 more
wiley   +1 more source

Lymphoma, multiple myeloma and leukaemia incidence in regions of Belarus most heavily contaminated by the Chernobyl accident

open access: yesInternational Journal of Cancer, EarlyView.
What's New? The 1986 Chernobyl accident led to widespread radioactive contamination across parts of Europe, with elevated childhood leukaemia rates observed in heavily affected areas of Ukraine. Data on long‐term haematological and other non‐thyroid cancer risk in the general population in heavily contaminated regions, however, remain limited.
Ljubica Zupunski   +10 more
wiley   +1 more source

Smoldering multiple myeloma: special considerations surrounding treatment on versus off clinical trials

open access: yesHaematologica, 2014
Elisabet E Manasanch   +6 more
doaj   +1 more source

Global Burden of Hematologic Malignancies From 1990 to 2021 With Projections to 2030: A Systematic Analysis for the Global Burden of Disease Study 2021

open access: yesiNew Medicine, EarlyView.
ABSTRACT This study aimed to comprehensively analyze the epidemiological trends and global burden of hematologic malignancies (HM) from 1990 to 2021 and to project trends up to the year 2030. Using data from the Global Burden of Disease (GBD) Study 2021, we analyzed the age‐standardized rates (ASRs) and the trends of HM from 1990 to 2021. Decomposition
Ziyuan Shen   +5 more
wiley   +1 more source

Targeting GRP78 and the Proteostasis Network to Break the Therapeutic Ceiling in Neuroendocrine Prostate Cancer

open access: yesiNew Medicine, EarlyView.
ABSTRACT HSPA5 (also known as GRP78/BiP) is a master regulator of the endoplasmic reticulum (ER) stress response and a key node in the proteostasis network. In neuroendocrine prostate cancer (NEPC), an aggressive, therapy‐refractory lineage that emerges under pressure from androgen receptor (AR) directed therapies, GRP78 is upregulated and co‐opted to ...
Amos Olalekan Akinyemi   +14 more
wiley   +1 more source

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