Results 91 to 100 of about 9,608,554 (246)
Journal of Medical Case ReportsBackground Surgery is the standard care for patients with early-stage lung cancer, and stereotactic body radiation therapy is an option for those who are medically inoperable or refuse surgery.
Naoko Ishida +7 more
doaj +1 more source
The ubiquitin system in normal and infected germinal center B cells
FEBS Letters, EarlyView.The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis +2 more
wiley +1 more source
Recurrences and second primary breast cancers in older women with initial early-stage disease.
, 2009 BACKGROUND: The association between common breast cancer therapies and recurrences and second primary breast cancers in older women is unclear, although older women are less likely to receive common therapies.
Enger, Shelley M. +10 more
core +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Assessment of a Resource and Descriptive Analysis of Participants with Multiple Primary Cancers
, 2023 We conducted an analysis of participants in the Nurses’ Health Study (NHS) and Nurses’ Health Study II (NHSII) cohorts, longitudinal studies with 34-47 years of follow-up, conducted jointly by Brigham and Women’s Hospital and Harvard School of Public ...
Mahoney, Matthew Brian
core +2 more sources
Multiple Primary Cancers in Patients with Breast and Skin Cancer [PDF]
, 2007 The extent of the problem The number of cancer survivors has been increasing dramatically and is expected to keep growing in the near future. In the Netherlands, a 38% increase of cancer survivors is estimated from 2005 to 2015, representing an ...
Soerjomataram, Isabelle +1 more
core +1 more source
Case Reports in Oncological Medicine, 2019 Gliosarcoma (GS) constitutes a minor fraction of primary glioblastoma (GBM), which is the most frequent malignant brain tumor in adults. Despite the fact that malignant gliomas are highly invasive, extracranial metastases are very rarely seen, and the ...
T. Capion +3 more
doaj +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Multiple primary cancers in esophageal squamous cell carcinoma: Incidence and implications
, 1998 Background. The occurrence of multiple primary cancers in the aerodigestive tract is a well-known phenomenon. This study aims to elucidate the incidence and the therapeutic and prognostic implications of a nonesophageal primary cancer in patients with ...
Wong, J +9 more
core +1 more source
Clinical Case ReportsA 41‐year‐old man developed three distinct primary malignancies—acute myeloid leukemia, male breast cancer, and metastatic colorectal cancer—within 7 years. This rare case highlights the evolving challenge of multiple primary cancers and demonstrates how
Abolfazl Khalafi‐Nezhad +3 more
doaj +1 more source