Results 1 to 10 of about 5,903,172 (376)

Multiple Sclerosis

The Lancet, 2018
A compelling body of evidence suggests that hormones derived from the gonads, adrenals, pituitary, and other organs may profoundly affect multiple sclerosis (MS) susceptibility and severity.
D. Reich, C. Lucchinetti, P. Calabresi
semanticscholar   +12 more sources

Multiple Sclerosis [PDF]

Autoimmune Diseases, 2011
Multiple sclerosis (MS) is a clinically and pathologically complex and heterogeneous disease of unknown etiology (Kantarci, 2008). The generally accepted view is, that primarily, MS is an autoimmune disease of the CNS that is precipitated by environmental factors in a genetically predisposed host (Kurtzke, 2005).
Sreeram Ramagopalan, David Dyment, Rachel Farrell, Noriko Isobe   +3 more
  +9 more sources

Multiple Sclerosis [PDF]

Global Advances in Health and Medicine, 2013
Multiple sclerosis (MS) is a chronic progressive demyelinating disease of the central nervous system. Common manifestations include paresthesias, diplopia, loss of vision, numbness or weakness of the limbs, bowel or bladder dysfunction, spasticity, ataxia, fatigue, and mental changes.
Samuel K. Ludwin, Jack Antel, Douglas L. Arnold   +2 more
  +7 more sources

Longitudinal relationships between disability and gait characteristics in people with MS

Scientific Reports, 2022
Longitudinal data are vital in order to understand intra individual gait changes with the progression of multiple sclerosis (MS). Therefore, the primary aim of this study was to explore the relationship between changes in disability with changes in major
Sapir Dreyer-Alster, Shay Menascu, Mark Dolev, Uri Givon, David Magalashvili, Anat Achiron, Alon Kalron   +6 more
doaj   +1 more source

Targeted cognitive game training enhances cognitive performance in multiple sclerosis patients treated with interferon beta 1-a

Journal of NeuroEngineering and Rehabilitation, 2021
Background Prevention of cognitive decline in Multiple Sclerosis (MS) is of major importance. We explored the effect of a 6 months computerized game training program on cognitive performance in MS patients with mild cognitive impairment. Methods This was
Shay Menascu, Roy Aloni, Mark Dolev, David Magalashvili, Keren Gutman, Sapir Dreyer-Alster, Franck Tarpin-Bernard, Ran Achiron, Gil Harari, Anat Achiron   +9 more
doaj   +1 more source

The MULTI-ACT model: the path forward for participatory and anticipatory governance in health research and care

Health Research Policy and Systems, 2022
The COVID-19 pandemic has unmasked even more clearly the need for research and care to form a unique and interdependent ecosystem, a concept which has emerged in recent years.
Paola Zaratin, Deborah Bertorello, Roberta Guglielmino, Danilo Devigili, Giampaolo Brichetto, Valentina Tageo, Gabriele Dati, Stephanie Kramer, Mario Alberto Battaglia, Monica Di Luca   +9 more
doaj   +1 more source

Cognitive rehabilitation in multiple sclerosis: Three digital ingredients to address current and future priorities

Frontiers in Human Neuroscience, 2023
Multiple sclerosis (MS) is a neurological chronic disease with autoimmune demyelinating lesions and one of the most common disability causes in young adults.
Andrea Tacchino, Jessica Podda, Valeria Bergamaschi, Ludovico Pedullà, Giampaolo Brichetto, Giampaolo Brichetto   +5 more
doaj   +1 more source

Rising prevalence of multiple sclerosis worldwide: Insights from the Atlas of MS, third edition

Multiple Sclerosis, 2020
Background: High-quality epidemiologic data worldwide are needed to improve our understanding of disease risk, support health policy to meet the diverse needs of people with multiple sclerosis (MS) and support advocacy efforts.
Clare Walton, Rachel King, Lindsay Rechtman, W. Kaye, E. Leray, R. Marrie, N. Robertson, N. La Rocca, B. Uitdehaag, I. van der Mei, M. Wallin, A. Helme, Ceri Angood Napier, N. Rijke, P. Baneke   +14 more
semanticscholar   +1 more source

Disease‐Modifying Therapies and Coronavirus Disease 2019 Severity in Multiple Sclerosis

Annals of Neurology, 2021
This study was undertaken to assess the impact of immunosuppressive and immunomodulatory therapies on the severity of coronavirus disease 2019 (COVID‐19) in people with multiple sclerosis (PwMS).
M. Sormani, N. de Rossi, I. Schiavetti, L. Carmisciano, C. Cordioli, L. Moiola, M. Radaelli, P. Immovilli, M. Capobianco, M. Trojano, P. Zaratin, G. Tedeschi, G. Comi, M. Battaglia, F. Patti, M. Salvetti   +15 more
semanticscholar   +1 more source

The genetic association of variants in CD6, TNFRSF1A and IRF8 to multiple sclerosis: a multicenter case-control study. [PDF]

PLoS ONE, 2011
In the recently published meta-analysis of multiple sclerosis genome-wide association studies De Jager et al. identified three single nucleotide polymorphisms associated to MS: rs17824933 (CD6), rs1800693 (TNFRSF1A) and rs17445836 (61.5 kb from IRF8). To
International Multiple Sclerosis Genetics Consortium
doaj   +1 more source