Results 71 to 80 of about 6,039,132 (349)

Cytokine, Chemokine, and Neurofilament Light Chain Signatures in LGI1 Autoimmune Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives To investigate the value of cytokine, chemokine, and neurofilament light chain (NfL) concentrations in predicting relapse risk, chronic epilepsy, and functional impairment in LGI1 autoimmune encephalitis (AE). Methods Cytokines/chemokines (IL‐1‐beta, IL‐2, IL‐4, IL‐5, IL‐6, IL‐8/CXCL8, IL‐10, IL‐12p70, IL‐13, IL‐17A, GM‐CSF, TNF ...
Albert Aboseif, Georgios Mangioris, Binxia Yang, Vanessa K. Pazdernik, Jeffrey W. Britton, Divyanshu Dubey, Eoin P. Flanagan, Sarosh R. Irani, Gregory S. Day, Charles L. Howe, A. Sebastian López‐Chiriboga, Andrew McKeon, John R. Mills, Yahel Segal, Michel Toledano, Ivana Vodopivec, Sean J. Pittock, Anastasia Zekeridou   +17 more
wiley   +1 more source

Spatial constraints and cognitive fatigue affect motor imagery of walking in people with multiple sclerosis

Scientific Reports, 2020
Motor imagery (MI) is the mental simulation of an action without any overt motor execution. Interestingly, a temporal coupling between durations of real and imagined movements, i.e., the so-called isochrony principle, has been demonstrated in healthy ...
Jessica Podda, Ludovico Pedullà, Margherita Monti Bragadin, Elisa Piccardo, Mario Alberto Battaglia, Giampaolo Brichetto, Marco Bove, Andrea Tacchino   +7 more
doaj   +1 more source

Altered human oligodendrocyte heterogeneity in multiple sclerosis

Nature, 2019
Oligodendrocyte pathology is increasingly implicated in neurodegenerative diseases as oligodendrocytes both myelinate and provide metabolic support to axons.
S. Jäkel, E. Agirre, A. Falcão, D. V. Bruggen, K. Lee, I. Knuesel, D. Malhotra, C. F. Constant, Anna C. Williams, G. Castelo-Branco   +9 more
semanticscholar   +1 more source

Quantitative Iron Measurements in the Basal Ganglia of NBIA Patients Using QSM: Insights From a Tertiary Center

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurodegeneration with brain iron accumulation (NBIA) comprises rare genetic disorders characterized by predominantly extrapyramidal symptoms and iron deposition in the basal ganglia. Conventional magnetic resonance imaging (MRI) detects qualitative changes but cannot accurately quantify iron accumulation. Quantitative susceptibility
Özge Uygun, Alpay Özcan, Fuat Kaan Aras, Evrim Bozdemir, Sibel Uğur İşeri, Koray Kırımtay, Arzu Karabay, Murat Gültekin, Nihan Hande Akçakaya, Orkhan Mammadov, Gülay Kır, Dilek İnce Günal, Neşe Tuncer, Fatma Betül Özdilek, Banu Özen Barut, Ercan Köse, Hülya Apaydın, Asuman Ali, Sultan Çağırıcı, Pınar Topaloğlu, Alp Dinçer, Zuhal Yapıcı   +21 more
wiley   +1 more source

Typical trident sign and cardiac involvement in a patient suspected to Sarcoidosis despite negative whole-body FDG-PET: a case report

Journal of Medical Case Reports, 2023
Background Sarcoidosis is a systemic inflammatory disease histologically defined by the non-caseation granulomas formation in different organs, most commonly lungs, liver, skin, gastrointestinal system, eyes, neurologic and cardiac system Case ...
Abootorab Shahmohammdi, Hora Heidari, Kosar Kohandel, Soheil Dousti, Rozita Doosti, Amir Reza Azimi, Zahra Shajari, Parham Rabiei, Sareh Shahmohammdi   +8 more
doaj   +1 more source

Neuronal vulnerability and multilineage diversity in multiple sclerosis

Nature, 2019
Multiple sclerosis (MS) is a neuroinflammatory disease with a relapsing–remitting disease course at early stages, distinct lesion characteristics in cortical grey versus subcortical white matter and neurodegeneration at chronic stages.
Lucas Schirmer, Dmitry Velmeshev, S. Holmqvist, Max Kaufmann, Sebastian Werneburg, Diane Jung, Stephanie Vistnes, J. Stockley, Adam M. H. Young, M. Steindel, Brian Tung, Nitasha Goyal, A. Bhaduri, Simone Mayer, J. B. Engler, O. Bayraktar, R. Franklin, M. Haeussler, R. Reynolds, D. Schafer, M. Friese, L. Shiow, A. Kriegstein, D. Rowitch   +23 more
semanticscholar   +1 more source

D-KEFS ST Failure Identifies Multiple Sclerosis Patients With Worse Objective and Self-Perceived Physical and Cognitive Disability

Frontiers in Psychology, 2019
Background and Objectives: The Brief Repeatable Battery of Neuropsychological Test (BRB-NT) does not explore the executive functions. We combined BRB-NT and Delis-Kaplan Executive Function System Sorting Test (D-KEFS ST) to obtain a more comprehensive ...
Alice Riccardi, Marco Puthenparampil, Francesca Rinaldi, Mario Ermani, Paola Perini, Paolo Gallo   +5 more
doaj   +1 more source

Assessment of lesions on magnetic resonance imaging in multiple sclerosis: practical guidelines

Brain : a journal of neurology, 2019
MRI has improved the diagnostic work-up of multiple sclerosis, but inappropriate image interpretation has contributed to misdiagnosis. Filippi et al. provide a practical guide to the proper recognition of multiple sclerosis lesions, including a thorough ...
M. Filippi, P. Preziosa, B. Banwell, F. Barkhof, O. Ciccarelli, N. de Stefano, J. Geurts, F. Paul, D. Reich, A. Toosy, A. Traboulsee, M. Wattjes, T. Yousry, A. Gass, C. Lubetzki, B. Weinshenker, M. Rocca   +16 more
semanticscholar   +1 more source

Practice Recommendations for Genetic Testing of Ataxias

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Over the past decade, significant advances in genetic testing for ataxia have improved diagnostic accuracy, informed clinical trial eligibility, guided treatment decisions, and enabled cascade testing of at‐risk relatives. While guidance exists for other neurogenetic conditions, there are no standardized guidelines on genetic ...
Sharan R. Srinivasan, Amy D. Mook, Michelle Rochman, Jin Yun Helen Chen, Weiyi Mu, George R. Wilmot, Liana S. Rosenthal, Wendy R. Uhlmann   +7 more
wiley   +1 more source

Lifetime exposure to smoking and substance abuse may be associated with late-onset multiple sclerosis: a population-based case-control study

BMC Neurology
Background Late-onset multiple sclerosis (LOMS), defined as the development of MS after the age of 50, has shown a substantial surge in incidence rates and is associated with more rapid progression of disability.
Naghmeh Abbasi Kasbi, Sajjad Ghane Ezabadi, Kosar Kohandel, Faezeh Khodaie, Amir Hossein Sahraian, Sahar Nikkhah Bahrami, Mahsa Mohammadi, Amir Almasi-Hashiani, Sharareh Eskandarieh, Mohammad Ali Sahraian   +9 more
doaj   +1 more source