Results 1 to 10 of about 1,015,687 (277)

Heuristic for Solving the Multiple Alignment Sequence Problem

open access: yesRevista de Matemática: Teoría y Aplicaciones, 2011
In this paper we developed a new algorithm for solving the problem of multiple sequence alignment (AM S), which is a hybrid metaheuristic based on harmony search and simulated annealing.
Roman Anselmo Mora Gutiérrez   +2 more
doaj   +1 more source

Multiple sequence alignment accuracy and evolutionary distance estimation

open access: yesBMC Bioinformatics, 2005
Background Sequence alignment is a common tool in bioinformatics and comparative genomics. It is generally assumed that multiple sequence alignment yields better results than pair wise sequence alignment, but this assumption has rarely been tested, and ...
Rosenberg Michael S
doaj   +1 more source

Cognitively Economical Heuristic for Multiple Sequence Alignment under Uncertainties

open access: yesAxioms, 2022
This paper introduces a heuristic for multiple sequence alignment aimed at improving real-time object recognition in short video streams with uncertainties.
Milan Gnjatović   +5 more
doaj   +1 more source

Multiple alignment by sequence annealing [PDF]

open access: yesBioinformatics, 2007
AbstractMotivation: We introduce a novel approach to multiple alignment that is based on an algorithm for rapidly checking whether single matches are consistent with a partial multiple alignment. This leads to a sequence annealing algorithm, which is an incremental method for building multiple sequence alignments one match at a time.
Schwartz, Ariel S., Pachter, Lior
openaire   +3 more sources

HAlign-G: rapid and low-memory multiple-genome aligner for large-scale closely related genomes

open access: yesGenome Biology
HAlign-G is a fast and memory-efficient tool for large-scale multiple genome alignment. Using BWT-FM-LIS with an optimized K-band algorithm and star alignment strategy, it supports intra-species (HAlign-G1) and cross-species (HAlign-G2) alignment ...
Pinglu Zhang   +8 more
doaj   +1 more source

Efficient implied alignment

open access: yesBMC Bioinformatics, 2020
Background Given a binary tree T $\mathcal {T}$ of n leaves, each leaf labeled by a string of length at most k, and a binary string alignment function ⊗, an implied alignment can be generated to describe the alignment of a dynamic homology for T ...
Alex J. Washburn, Ward C. Wheeler
doaj   +1 more source

Multiple sequence alignments in linguistics [PDF]

open access: yesProceedings of the EACL 2009 Workshop on Language Technology and Resources for Cultural Heritage, Social Sciences, Humanities, and Education - LaTeCH-SHELT&R '09, 2009
In this study we apply and evaluate an iterative pairwise alignment program for producing multiple sequence alignments, ALPHAMALIG (Alonso et al., 2004), using as material the phonetic transcriptions of words used in Bulgarian dialectological research. To evaluate the quality of the multiple alignment, we propose two new methods based on comparing each
Prokić, J., Wieling, M., Nerbonne, J.
openaire   +2 more sources

Segment-based multiple sequence alignment [PDF]

open access: yesBioinformatics, 2008
Abstract Motivation: Many multiple sequence alignment tools have been developed in the past, progressing either in speed or alignment accuracy. Given the importance and wide-spread use of alignment tools, progress in both categories is a contribution to the community and has driven research in the field so far. Results: We
Rausch, T.   +5 more
openaire   +3 more sources

Sigma: multiple alignment of weakly-conserved non-coding DNA sequence

open access: yesBMC Bioinformatics, 2006
Background Existing tools for multiple-sequence alignment focus on aligning protein sequence or protein-coding DNA sequence, and are often based on extensions to Needleman-Wunsch-like pairwise alignment methods. We introduce a new tool, Sigma, with a new
Siddharthan Rahul
doaj   +1 more source

LCSkPOA: enabling banded semi-global partial order alignments via efficient and accurate backbone generation through extended LCSk++

open access: yesBMC Bioinformatics
Background Most multiple sequence alignment and string-graph alignment algorithms focus on global alignment, but many applications exist for semi-global and local string-graph alignment.
Minindu Weerakoon   +2 more
doaj   +1 more source

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