Results 1 to 10 of about 483,132 (293)
Strategies for Multiple Sequence Alignment [PDF]
BioTechniques, 2002 We present an overview of multiple sequence alignments to outline the practical consequences for the choices among different techniques and parameters. We begin with a discussion of the scoring methods for quantifying the quality of a multiple sequence ...
Hugh B. Nicholas +2 more
doaj +4 more sources
E-PROBCONS: Enhanced PROBCONS for Multiple Sequence Alignment [PDF]
IJCI International Journal of Computers and Information, 2020 — the perfect alignment between three or more sequences of protein, RNA or DNA is a very difficult task in Bioinformatics. There are many techniques for alignment of multiple sequences.
arabi keshk, Hamdy Mousa, Eman Mohamed
doaj +4 more sources
Recursive MAGUS: Scalable and accurate multiple sequence alignment. [PDF]
PLoS Computational Biology, 2021 Multiple sequence alignment tools struggle to keep pace with rapidly growing sequence data, as few methods can handle large datasets while maintaining alignment accuracy.
Vladimir Smirnov
doaj +2 more sources
Advances in post-processing methods for multiple sequence alignment [PDF]
Frontiers in GeneticsThe reliability of multiple sequence alignment (MSA) results directly determines the credibility of the conclusions drawn from biological research. However, MSA is inherently an NP-hard problem, making it theoretically impossible to guarantee a globally ...
Yixiao Zhai +3 more
doaj +2 more sources
Progressive multiple sequence alignment with indel evolution [PDF]
BMC Bioinformatics, 2018 Background Sequence alignment is crucial in genomics studies. However, optimal multiple sequence alignment (MSA) is NP-hard. Thus, modern MSA methods employ progressive heuristics, breaking the problem into a series of pairwise alignments guided by a ...
Massimo Maiolo +3 more
doaj +2 more sources
On the Edge of Web-Based Multiple Sequence Alignment Services
Tsinghua Science and Technology, 2012 There are many web-based multiple sequence alignment services accessible around the world. However, many researchers working on biological sequence analysis still struggle with inefficient, unfriendly user interface, and limited capability multiple ...
Ken D. Nguyen
doaj +3 more sources
ClipKIT: A multiple sequence alignment trimming software for accurate phylogenomic inference. [PDF]
PLoS Biol, 2020 Steenwyk JL +4 more
europepmc +2 more sources
Multiple sequence alignments [PDF]
Current Opinion in Structural Biology, 2005 Multiple sequence alignments are very widely used in all areas of DNA and protein sequence analysis. The main methods that are still in use are based on 'progressive alignment' and date from the mid to late 1980s. Recently, some dramatic improvements have been made to the methodology with respect either to speed and capacity to deal with large numbers ...
Iain M, Wallace +2 more
openaire +3 more sources
Recent evolutions of multiple sequence alignment algorithms.
PLoS Computational Biology, 2007 Cédric Notredame
doaj +2 more sources
EMMA: a new method for computing multiple sequence alignments given a constraint subset alignment
Algorithms for Molecular Biology, 2023 Background Adding sequences into an existing (possibly user-provided) alignment has multiple applications, including updating a large alignment with new data, adding sequences into a constraint alignment constructed using biological knowledge, or ...
Chengze Shen +3 more
doaj +1 more source