Results 121 to 130 of about 756,544 (331)

HMMerge: an ensemble method for multiple sequence alignment. [PDF]

Bioinform Adv, 2023
Park M, Warnow T.
europepmc   +1 more source

Multiple alignment of DNA-B sequences from CMMGV, EACMCV, EACMV, EACMKV, EACMMV, EACMZV, SACMV (7 "species")

, 2020
Divya Dubey, J. Steen Hoyer, Siobain Duffy   +2 more
openalex   +1 more source

An Ant-Based Model for Multiple Sequence Alignment [PDF]

, 2008
Frédéric Guinand, Yoann Pigné
openalex   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Multiple sequence alignment for identification of positive selection

, 2020
Yun‐Juan Bao
openalex   +1 more source

Current Methods for Automated Filtering of Multiple Sequence Alignments Frequently Worsen Single-Gene Phylogenetic Inference [PDF]

, 2015
Ge Tan, Matthieu Muffato, Christian Ledergerber, Javier Herrero, Nick Goldman, Manuel Gil, Christophe Dessimoz   +6 more
openalex   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

Multiple sequence alignment based on deep reinforcement learning with self-attention and positional encoding. [PDF]

Bioinformatics, 2023
Liu Y, Yuan H, Zhang Q, Wang Z, Xiong S, Wen N, Zhang Y.   +6 more
europepmc   +1 more source

MAVID: Constrained Ancestral Alignment of Multiple Sequences [PDF]

, 2004
Nicolas Bray, Lior Pachter
openalex   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source