Multiple sequence alignment with hierarchical clustering
Nucleic Acids Research, 1988 An algorithm is presented for the multiple alignment of sequences, either proteins or nucleic acids, that is both accurate and easy to use on microcomputers. The approach is based on the conventional dynamic-programming method of pairwise alignment.
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Diffusion‐based size determination of solute particles: a method adapted for postsynaptic proteins
FEBS Open Bio, EarlyView.We present a diffusion‐based approach for measuring the size of macromolecules and their complexes, and demonstrate its use on postsynaptic proteins. The method requires fluorescein‐labelled protein samples, a microfluidic device that maintains laminar flow for said samples, a microscope recording the emitted fluorescent signals, and an analytic ...
András László Szabó +7 more
wiley +1 more source
Multiple Sequence Alignment Tools on the Web
BioTechniques, 2000 Giles J. Gaskell
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PacRAT: a program to improve barcode-variant mapping from PacBio long reads using multiple sequence alignment. [PDF]
Bioinformatics, 2022 Yeh CC +3 more
europepmc +1 more source
Pro-malign: Multiple Sequence Alignment Algorithm using Approached Profile [PDF]
, 2018 Ahmed Mokaddem +2 more
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FEBS Open Bio, EarlyView.Angubindin‐1 binds angulin‐1/‐3 at tricellular tight junctions, enhancing intestinal macromolecule permeation. Alanine scanning identified six essential residues (L562, L598, E638, V640, Y643, and K644) of angubindin‐1 critical for binding to angulin‐1/‐3 and permeation‐enhancing activity, providing insights for the development of targeted noninvasive ...
Taiki Kuzu +8 more
wiley +1 more source
Relative model selection of evolutionary substitution models can be sensitive to multiple sequence alignment uncertainty. [PDF]
BMC Ecol Evol, 2021 Spielman SJ, Miraglia ML.
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The impact of Hnrnpl deficiency on transcriptional patterns of developing muscle cells
FEBS Open Bio, EarlyView.We performed nanopore whole‐transcriptome sequencing comparing RNA from Hnrnpl‐knockdown versus control C2C12 myoblasts to investigate the contributions of Hnrnpl to muscle development. Our results indicate that Hnrnpl regulates the expression of genes involved with Notch signaling and skeletal muscle, particularly splicing patterns of specific muscle ...
Hannah R. Littel +8 more
wiley +1 more source
Study of Basic Local Alignment Search Tool (BLAST) and Multiple Sequence Alignment (Clustal- X) of Monoclonal mice/human antibodies [PDF]
, 2021 Ivan Vito Ferrari, Paolo Di Patrizio
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