Results 151 to 160 of about 1,526,772 (381)

Multiple Sequence Alignment Menggunakan Nature-Inspired Metaheuristic Algorithms [PDF]

, 2017
Multiple sequence alignment adalah proses dasar yang sering dibutuhkan dalam mengolah beberapa sequence yang berhubungan dengan bioinformatika. Apabila multiple sequence alignment telah selesai dikerjakan, maka dapat dilakukan analisis-analisis lain yang
Shahab, Muhammad Luthfi
core  

Approximation algorithms for multiple sequence alignment

Theoretical Computer Science, 1994
AbstractWe consider the problem of aligning of k sequences of length n. The cost function is sum of pairs, and satisfies triangle inequality. Earlier results on finding approximation algorithms for this problem are due to Gusfield (1991) who achieved an approximation ratio of 2 − 2k, and Pevzner (1992) who improved it to 2 − 3k.
Pavel A. Pevzner, Eugene L. Lawler, Vineet Bafna   +2 more
openaire   +3 more sources

MARS: improving multiple circular sequence alignment using refined sequences

BMC Genomics, 2017
A fundamental assumption of all widely-used multiple sequence alignment techniques is that the left- and right-most positions of the input sequences are relevant to the alignment.
Lorraine A. K. Ayad, S. Pissis
semanticscholar   +1 more source

TOMM20 as a driver of cancer aggressiveness via oxidative phosphorylation, maintenance of a reduced state, and resistance to apoptosis

Molecular Oncology, EarlyView.
TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam, Megan E. Roche, Zhao Lin, Diana Whitaker‐Menezes, Victor Diaz‐Barros, Eurico Serrano, Maria Paula Martinez Cantarin, Nancy J. Philp, Atrayee Basu Mallick, Ubaldo Martinez‐Outschoorn   +9 more
wiley   +1 more source

PoMSA: An Efficient and Precise Position-based Multiple Sequence Alignment Technique [PDF]

arXiv, 2017
Analyzing the relation between a set of biological sequences can help to identify and understand the evolutionary history of these sequences and the functional relations among them. Multiple Sequence Alignment (MSA) is the main obstacle to proper design and develop homology and evolutionary modeling applications since these kinds of applications ...
arxiv  

Propositionalisation of multiple sequence alignments using probabilistic models [PDF]

, 2008
Multiple sequence alignments play a central role in Bioinformatics. Most alignment representations are designed to facilitate knowledge extraction by human experts.
Holmes, Geoffrey, Mutter, Stefan, Pfahringer, Bernhard   +2 more
core   +2 more sources

TCS: a web server for multiple sequence alignment evaluation and phylogenetic reconstruction

Nucleic Acids Res., 2015
This article introduces the Transitive Consistency Score (TCS) web server; a service making it possible to estimate the local reliability of protein multiple sequence alignments (MSAs) using the TCS index.
Jia-Ming Chang, Paolo Di Tommaso, Vincent Lefort, O. Gascuel, C. Notredame   +4 more
semanticscholar   +1 more source

Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM

Molecular Oncology, EarlyView.
CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak, Żaneta Zarębska, Marcin P. Sajek, Adriana Grabowska, Alessia Buratin, Paweł Głodowicz, Julia O. Misiorek, Konrad Kuczyński, Stefania Bortoluzzi, Marek Żywicki, Jan G. Kosiński, Agnieszka Rybak‐Wolf, Rafał Piestrzeniewicz, Anna M. Barciszewska, Katarzyna Rolle   +14 more
wiley   +1 more source

Automatic detection of anchor points for multiple sequence alignment

BMC Bioinformatics, 2010
Background Determining beforehand specific positions to align (anchor points) has proved valuable for the accuracy of automated multiple sequence alignment (MSA) software.
Pitschi Florian, Devauchelle Claudine, Corel Eduardo   +2 more
doaj   +1 more source

New Computational Approaches For Multiple Rna Alignment And Rna Search [PDF]

, 2009
In this thesis we explore the the theory and history behind RNA alignment. Normal sequence alignments as studied by computer scientists can be completed in O(n2) time in the naive case. The process involves taking two input sequences and finding the list
DeBlasio, Daniel
core   +1 more source