Results 91 to 100 of about 2,232,801 (311)
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Testing for Multiple Structural Changes with Non-Homogeneous Regressors [PDF]
This paper investigates tests for multiple structural changes with non-homogeneous regressors, such as polynomial trends. We consider exponential-type, supremum-type and average-type tests as well as the corresponding weighted-type tests suggested in the
Eiji Kurozumi
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Application of statistical contrasts to mean refractive state
African Vision and Eye Health, 2006 Testing for differences between specific groups or combinations of groups is referred to as comparison or contrast testing. Statistical significance of comparisons can be assessed by first forming contrasts and then testing for their ...
S Abelman
doaj +1 more source
Multiple testing with persistent homology
CoRR, 2018 In this paper we propose a computationally efficient multiple hypothesis testing procedure for persistent homology. The computational efficiency of our procedure is based on the observation that one can empirically simulate a null distribution that is universal across many hypothesis testing applications involving persistence homology.
Mikael Vejdemo-Johansson +1 more
openaire +2 more sources
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Development programs for one-shot systems using multiple-state design reliability models [PDF]
Design reliability at the beginning of a product development program is typically low and development costs can account for a large proportion of total product cost.
Vardeman, Stephen B. +1 more
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Testing Programming Skills with Multiple Choice Questions
Informatics in Education, 2004 Multiple choice questions are a convenient and popular means of testing beginning students in programming courses. However, they are qualitatively different from exam questions.
CLARK David
doaj +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Oracles for distributed testing
, 2011 Copyright @ 2010 IEEE. Personal use of this material is permitted. Permission from IEEE must be obtained for all other users, including reprinting/ republishing this material for advertising or promotional purposes, creating new collective works for ...
Hierons, RM
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