Results 111 to 120 of about 2,232,801 (311)

Time-series characteristics of UK commercial property returns: testing for multiple changes in persistence

open access: yes, 2013
The random-walk hypothesis, vis-à-vis asset prices , suggests that prices traded in a market cannot be predicted based on historical information. Employing unsecuritised UK commercial property returns, we analyze this hypothesis, investigating multiple ...
Leone, V, Coleman, S
core  

Partial Knowledge in Multiple-Choice Testing [PDF]

open access: yesپژوهش در نظام‌های آموزشی, 2011
The intent of this study was to discover the nature of (partial) knowledge as estimated by the multiple-choice (MC) test method. An MC test of vocabulary, including 20 items, was given to 10 participants.
Ali Asghar Rostami Abusaeedi
doaj  

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Multiple testing problems

open access: yes, 2019
Statistical hypothesis testing is used while analyzing experimental data. This thesis is focused on multiple testing, which means testing many hypotheses simultaneously, and multiple testing problems occurring while running multiple hypotheses tests ...
Turzová, Kristína
core  

Bayesian Frequentist Multiple Testing

open access: yes, 2018
We introduce a Bayesian approach to multiple testing. The method is an extension of the false discovery rate (FDR) method due to Benjamini and Hochberg (1995).
Larry Wasserman (5362715)   +1 more
core   +1 more source

Interactive identification of individuals with positive treatment effect while controlling false discoveries

open access: yesJournal of Causal Inference
Out of the participants in a randomized experiment with anticipated heterogeneous treatment effects, is it possible to identify which subjects have a positive treatment effect?
Duan Boyan   +2 more
doaj   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

New metrics for multiple testing with correlated outcomes. [PDF]

open access: yesFront Appl Math Stat, 2023
Mathur MB, VanderWeele TJ.
europepmc   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

Home - About - Disclaimer - Privacy