Results 101 to 110 of about 37,255 (173)
Hsp90-containing multiprotein complexes in the eukaryotic microbe Achlya
Cell Stress & Chaperones, 1998 In the oomycete fungus Achlya ambisexualis, hyphae of the male strain undergo sexual differentiation in the presence of the steroid hormone antheridiol. Earlier studies demonstrated that antheridiol binds with high affinity to a 9S multiprotein complex from A. ambisexualis cytosols.
S A, Brunt +3 more
openaire +3 more sources
Alzheimer's &Dementia, Volume 22, Issue 3, March 2026.Abstract Emerging evidence highlights the central role of peripheral immune–metabolic regulation in the pathogenesis of Alzheimer's disease and related dementias (ADRD). Among peripheral organs, the spleen has gained increasing attention as a critical immune–metabolic hub linking systemic homeostasis to central neurodegeneration.
Jingsi Yan +7 more
wiley +1 more source
The TOR Signaling Pathway in Spatial and Temporal Control of Cell Size and Growth
Frontiers in Cell and Developmental Biology, 2017 Cell size is amenable by genetic and environmental factors. The highly conserved nutrient-responsive Target of Rapamycin (TOR) signaling pathway regulates cellular metabolic status and growth in response to numerous inputs.
Suam Gonzalez, Charalampos Rallis
doaj +1 more source
Author Correction: HR-Bac, a toolbox based on homologous recombination for expression, screening and production of multiprotein complexes using the baculovirus expression system. [PDF]
Sci Rep, 2022 Kolesnikova O +11 more
europepmc +1 more source
Understanding Neurodegenerative Diseases From the −Omics Perspective: Lessons Learnt
Annals of Neurology, Volume 99, Issue 3, Page 566-587, March 2026.[Color figure can be viewed at www.annalsofneurology.org] As the population ages, certain neurodegenerative diseases (NDs) are becoming a major health issue. For this reason, this review will focus on the most common ND with onset after 65 years old; Alzheimer's disease, Parkinson's disease, Lewy body dementia, and frontotemporal dementia.
Laura Ibanez +5 more
wiley +1 more source
Inflammasome — a new look at the therapy of cardiovascular diseases. Part II
Российский кардиологический журналThe role of inflammasomes in cardiovascular diseases has not been sufficiently studied at present. However, there are a number of recent studies showing the participation of these multiprotein complexes in the development and progression of ...
A. A. Rubinstein +5 more
doaj +1 more source
Disassembly of intact multiprotein complexes in the gas phase
Current Opinion in Structural Biology, 1999 The observation of multiprotein complexes by mass spectrometry formerly relied upon chemical cross-linking to maintain interactions. Recent technological developments have enabled the observation of intact macromolecular complexes without modification.
Rostom, A, Robinson, C
openaire +2 more sources
ChemistryEurope, Volume 4, Issue 3, March 2026.A newly discovered fluorogenic DNAzyme, RFD‐CD3, enables rapid and sensitive detection of Clostridioides difficile and—unexpectedly—Listeria monocytogenes, making it the first dual‐responsive DNAzyme for two unrelated bacterial pathogens. Its strong catalytic efficiency, pH‐tolerant activity, and modular trans‐acting design position it as a promising ...
Soyeon Lee +4 more
wiley +1 more source
Clinical and Translational Medicine, Volume 16, Issue 3, March 2026.Pyroptosis, apoptosis and necroptosis of macrophages occur concurrently during atherosclerosis. Galetein‐3 and NLRP3 are highly expressed in atherosclerotic lesions. Galectin‐3 is principally expressed in macrophages within atherosclerotic plaques. Galectin‐3 interacts with NLRP3, activates TLR4/MyD88/NF‐κB/NLRP3 signal axis, and promotes PANoptosis ...
Zihui Yuan +5 more
wiley +1 more source
PI3Kδ Forms Distinct Multiprotein Complexes at the TCR Signalosome in Naïve and Differentiated CD4<sup>+</sup> T Cells. [PDF]
Front Immunol, 2021 Luff DH +8 more
europepmc +1 more source