Results 111 to 120 of about 4,566 (189)

Multispecific DNA-Coatings for Self-Assembly

DNA-coated particles are promising as building blocks for functional and finite-sized assemblies because they can be programmed with orthogonal interactions owing to the sequence-specific hybridization of DNA strands. To fully exploit this programmability, it is important to develop particles with coatings that incorporate multiple distinct DNA ...
Stevens, T. C. M., van der Sluis, A., Voets, I. K., Moerman, P. G.   +3 more
openaire   +2 more sources

Selectivity of OATs and OATPs for Endogenous Metabolites and Signaling Molecules <i>In Vivo</i>. [PDF]

ACS Omega
Nigam AK, Falah K, Momper JD, Nigam SK.
europepmc   +1 more source

Evolution of bispecific and multispecific antibodies in cancer therapy. [PDF]

Lancet Reg Health Eur
Fontana E, Grochot R, Kotecki N, Doger B, Nannini S, de Miguel M.   +5 more
europepmc   +1 more source

Nomenclature of therapies in inflammatory bowel disease: A journey through time and terminology. [PDF]

Inflamm Bowel Dis
Colwill M, Patel K, Sebastian S, Din S, Honap S.   +4 more
europepmc   +1 more source

Intramolecular trimerization, a novel strategy for making multispecific antibodies with controlled orientation of the antigen binding domains

Here, we describe a new strategy that allows the rapid and efficient engineering of mono and multispecific trivalent antibodies. By fusing single-domain antibodies from camelid heavy-chain-only immunoglobulins (VHHs) to the N-terminus of a human collagen
Cuesta, Angel M., Blanco-Toribio, Ana, Merino, Nekane, Oliva Miguel, Baldomero, Harwood, Seandean Lykke, Mølgaard, Kasper, Blanco, Francisco, Navarro, Rocio, Villate, Maider, Compte, Marta, Bonet Martínez, Jaume, 1982-, Muñoz-Briones, Clara, Sørensen, Karen Marie Juul, Sanz, Laura, Alvarez-Cienfuegos, Ana, Nuñez-Prado, Natalia, Alvarez-Vallina, Luis   +16 more
core  

Differential T cell reactivation by two PD-L1 nanobodies through blockade alone or blockade with internalization. [PDF]

Sci Rep
Lee JH, Cho SY, Lee HE, Lee S.
europepmc   +1 more source

Bispecific and multispecific immune engagers for redirecting innate and adaptive immunity against hematologic cancers. [PDF]

Discov Oncol
Ardah MT, Abdulsahib WK, Jasim IK, Malathi H, Patro PS, Anand DA, Mukherjee G, Sinha A, Aminqulov S.   +8 more
europepmc   +1 more source

B cells enable autoreactive T cells to avoid suppression. [PDF]

Proc Natl Acad Sci U S A
Funsten M, de Pooter R, Varanasi V, Burrows M, Block K, Kuznetsov A, Serreze D, Huang H, Chervonsky A.   +8 more
europepmc   +1 more source

Editorial: Bispecific antibodies and their conjugates in solid tumors and hematological malignancies. [PDF]

Front Immunol
Püsküllüoğlu M, Pacholczak-Madej R.
europepmc   +1 more source

Pharmacological considerations for next-generation protein therapeutics in cardiovascular disease. [PDF]

J Pharmacol Exp Ther
Lin E, Momin N.
europepmc   +1 more source