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Broadly Protective Antibody-Like Vaccines Against Highly Pathogenic Coronaviruses. [PDF]
Helal A +20 more
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Unlocking the promise of innate biology through the HLA-G/ILT2/ILT4 pathway. [PDF]
Beers C, Ilaria RL, Luke JJ.
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First confirmation of <i>Brachycladium atlanticum</i> as aetiological agent of pulmonary pathologies in a common dolphin (<i>Delphinus delphis</i>). [PDF]
Estarrona A +7 more
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Multispecific monoclonal antibodies
Immunology Today, 1986Monoclonal antibodies are frequently shown to participate in unexpected cross reactions involving two apparently dissimilar antigens. This can be attributed either to partial epitope identity or to irrelevant interactions involving additional binding capacity of the antibody.
D, Isenberg, C, Dudeney, W, Williams
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Multispecific myeloid defensins
Current Opinion in Hematology, 2007This review describes recent progress in our understanding of defensins and their contributions to innate immunity. Defensins are small, cysteine-rich endogenous antibiotic peptides. Human neutrophils contain large amounts of three alpha-defensins (HNP-1-HNP-3), and smaller amounts of a fourth, HNP-4. Monocytes and macrophages generally lack defensins,
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Expression of Multispecific Antibodies
Bi- and multispecific antibody formats allow the development of new therapeutic strategies to address previously unmet medical needs. However, due to the increased complexity (e.g., the interface design and the presence of multiple binders), such molecules are generally more challenging to express and purify compared to standard monoclonal antibodies ...Megane, Peltret +5 more
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Multispecificity of Monoclonal Rheumatoid Factor
International Archives of Allergy and Applied Immunology, 2009The study involved a monoclonal rheumatoid factor referred to as RF-AN, obtained by Steinitz and his associates from IgG-reactive human lymphocytes ‘immortalized’ by infection with Epstein-Barr virus. RF-AN combined with red blood cells (RBC) sensitized by either human or rabbit IgG antibodies.
F, Milgrom, Z, Swierczynska
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