Results 11 to 20 of about 19,858 (239)
Multitarget Vulnerable Plaque Imaging [PDF]
Circulation: Cardiovascular Imaging, 2017 The search for the vulnerable plaque has been a prolonged, circuitous journey that despite considerable investment and resource expenditure has hitherto failed to alter clinical practice. The rationale remains enticing. We have known for some time that plaques at risk of rupture and precipitating myocardial infarction and stroke have certain ...
Marc R, Dweck, Zahi A, Fayad
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Multitarget tracking using the joint multitarget probability density [PDF]
IEEE Transactions on Aerospace and Electronic Systems, 2005 This work addresses the problem of tracking multiple moving targets by recursively estimating the joint multitarget probability density (JMPD). Estimation of the JMPD is done in a Bayesian framework and provides a method for tracking multiple targets which allows nonlinear target motion and measurement to state coupling as well as nonGaussian target ...
C. Kreucher, K. Kastella, A.O. Hero
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Hippocampal Avoidance in Multitarget Radiosurgery [PDF]
Cureus, 2021 Brain metastases are a common complication for patients diagnosed with cancer. As stereotactic radiosurgery (SRS) becomes a more prevalent treatment option for patients with many brain metastases, further research is required to better characterize the ability of SRS to treat large numbers of metastases (≥4) and the impact on normal brain tissue and ...
Gude, Zachary +3 more
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A Review of the Development of Multitarget Molecules against HIV-TB Coinfection Pathogens
Molecules, 2023 The human immunodeficiency virus (HIV) produces the pathologic basis of acquired immunodeficiency syndrome (AIDS). An increase in the viral load in the body leads to a decline in the number of T lymphocytes, compromising the patient’s immune system. Some
Debora Inacio Leite +9 more
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Multitarget Approaches against Multiresistant Superbugs [PDF]
ACS Infectious Diseases, 2020 Despite efforts to develop new antibiotics, antibacterial resistance still develops too fast for drug discovery to keep pace. Often, resistance against a new drug develops even before it reaches the market. This continued resistance crisis has demonstrated that resistance to antibiotics with single protein targets develops too rapidly to be sustainable.
Declan Alan Gray, Michaela Wenzel
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Molecules, 2018 A series of macrocyclic pyrido-pentapeptide candidates 2–6 were synthesized by using N,N-bis-[1-carboxy-2-(benzyl)]-2,6-(diaminocarbonyl)pyridine 1a,b as starting material.
Abd El-Galil E. Amr +5 more
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Frontiers in Pharmacology, 2021 Objectives: Zeel T (Ze14) is a multicomponent medicinal product. Initial preclinical data suggested a preventive effect on cartilage degradation. Clinical observational studies demonstrated that Ze14 reduced symptoms of osteoarthritis (OA), including ...
Christelle Sanchez +9 more
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Pharmaceuticals, 2023 Alternative medicines, especially herbal remedies, have been employed to treat infections and metabolism-related chronic inflammation because their safety and multidimensional therapeutic potential outweigh those of synthetic drugs. So Shiho Tang (SSHT),
Nguyen Khoi Song Tran +4 more
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Multitarget Therapeutics for Neurodegenerative Diseases [PDF]
BioMed Research International, 2020 No abstract ...
Moustafa T. Gabr, Samir Yahiaoui
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Molecules, 2020 A series of 27 compounds of general structure 2,3-dihydro-benzo[1,4]oxazin-4-yl)-2-{4-[3-(1H-3indolyl)-propyl]-1-piperazinyl}-ethanamides, Series I: 7(a–o) and (2-{4-[3-(1H-3-indolyl)-propyl]-1-piperazinyl}-acetylamine)-N-(2-morfolin-4-yl-ethyl ...
Christopher Cerda-Cavieres +13 more
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