Results 31 to 40 of about 34,376 (260)

Uncovering the Potential Mechanisms of Coptis chinensis Franch. for Serious Mental Illness by Network Pharmacology and Pharmacology-Based Analysis

Drug Design, Development and Therapy, 2022
Yiyu Qi,1 Saijia Ni,2 Xia Heng,1 Shuyue Qu,1 Pingyuan Ge,1 Xin Zhao,1 Zengying Yao,2 Rui Guo,3 Nianyun Yang,1 Qichun Zhang,2 Huaxu Zhu1 1Department of Traditional Chinese Medicine Processing and Preparation, Nanjing University of Chinese Medicine ...
Qi Y, Ni S, Heng X, Qu S, Ge P, Zhao X, Yao Z, Guo R, Yang N, Zhang Q, Zhu H   +10 more
doaj  

Evaluation of the analgesic effect of 4-anilidopiperidine scaffold containing ureas and carbamates [PDF]

, 2016
Fentanyl is a powerful opiate analgesic typically used for the treatment of severe and chronic pain, but its prescription is strongly limited by the well-documented side-effects.
Benyhe, Sa ́ndor, CARRADORI, Simone, Csaba To ̈mbo ̈ly, Erdei, Anna I., Ferenc O. ̈tvos, Ferenc Za ́dor, Fidanza, Lorenzo, Marzoli, Francesca, Mirzaie, Sako, MOLLICA, Adriano, MONTI, LUDOVICA, Moriello, Aniello Schiano, Novellino, Ettore, Petrocellis, Luciano De, PIERETTI, stefano, Samavati, Reza, STEFANUCCI, AZZURRA, Szabolcs Dvora ́csko, Szucs, Edina   +18 more
core   +1 more source

Multitargeted therapy of cancer by silymarin [PDF]

Cancer Letters, 2008
Silymarin, a flavonolignan from milk thistle (Silybum marianum) plant, is used for the protection against various liver conditions in both clinical settings and experimental models. In this review, we summarize the recent investigations and mechanistic studies regarding possible molecular targets of silymarin for cancer prevention.
Kumaraguruparan, Ramasamy, Rajesh, Agarwal   +1 more
openaire   +2 more sources

A Scalable Algorithm for Tracking an Unknown Number of Targets Using Multiple Sensors

, 2016
We propose a method for tracking an unknown number of targets based on measurements provided by multiple sensors. Our method achieves low computational complexity and excellent scalability by running belief propagation on a suitably devised factor graph.
Braca, Paolo, Hlawatsch, Franz, Meyer, Florian, Willett, Peter   +3 more
core   +1 more source

Multitarget Molecular Hybrids of Cinnamic Acids

Molecules, 2014
In an attempt to synthesize potential new multitarget agents, 11 novel hybrids incorporating cinnamic acids and paracetamol, 4-/7-hydroxycoumarin, benzocaine, p-aminophenol and m-aminophenol were synthesized.
Aikaterini Peperidou, Dorothea Kapoukranidou, Christos Kontogiorgis, Dimitra Hadjipavlou-Litina   +3 more
doaj   +1 more source

A Smo/Gli multitarget hedgehog pathway inhibitor impairs tumor growth [PDF]

, 2019
Pharmacological Hedgehog (Hh) pathway inhibition has emerged as a valuable anticancer strategy. A number of small molecules able to block the pathway at the upstream receptor Smoothened (Smo) or the downstream effector glioma-associated oncogene 1 (Gli1)
Balducci, Silvia, BASILI, IRENE, Botta, Bruno, Bufalieri, Francesca, Caimano, Miriam, Di Marcotullio, Lucia, Ghirga, Francesca, Infante, Paola, LORICCHIO, ELENA, LOSPINOSO SEVERINI, LUDOVICA, Maroder, Marella, Moretti, Marta, Mori, Mattia, Quaglio, Deborah, ROMEO, ISABELLA   +14 more
core   +1 more source

Multiple-input multiple-output least-squares constant modulus algorithms [PDF]

, 2003
Published ...
Constantinides, AG, Sansrimahachai, P, Ward, DB   +2 more
core   +1 more source

Multitargeted therapy of cancer by lycopene [PDF]

Cancer Letters, 2008
Lycopene (psi,psi-carotene) is the most abundant carotenoid in tomatoes and is the red pigment of not only tomatoes but also rosehips, watermelon, papaya, pink grapefruit, and guava. Unlike beta-carotene, lycopene lacks a beta-ionone ring and therefore has no pro-vitamin A activity.
Richard B, van Breemen, Natasa, Pajkovic
openaire   +2 more sources

Controlled Tracking in Urban Terrain: Closing the Loop

, 2018
We investigate the challenging problem of integrating detection, signal processing, target tracking, and adaptive waveform scheduling with lookahead in urban terrain.
Barbosa, Patricia R., Chong, Edwin K. P., Li, Yun, Moran, Bill, Sarkale, Yugandhar, Suvorova, Sofia   +5 more
core   +1 more source

New Multitarget Hybrids Bearing Tacrine and Phenylbenzothiazole Motifs as Potential Drug Candidates for Alzheimer’s Disease

Molecules, 2019
Research on neurodegenerative brain disorders, namely the age-dependent Alzheimer’s disease (AD), has been intensified in the last decade due to the absence of a cure and the recognized increasing of life expectancy for populations.
Rajeshwari Rajeshwari, Karam Chand, Emanuel Candeias, Sandra M. Cardoso, Sílvia Chaves, M. Amélia Santos   +5 more
doaj   +1 more source